<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32847

Description F-box-like/WD repeat-containing protein TBL1X isoform a
SequenceMTELTGTSSRCCPRPARRGAMQSPVDHVQRLRGREGGSHSASTSSQRGEAKMSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAASAATSTTAGVSQQNPPKNAQTPVNGEETRAHDINNHVKPMEVDGEVEIPSNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGCSTQLVLRHCIREGGHDVPSNKDVTSLDWNTDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCERPVKTFQGHTNEVNAIKWDPSGILLASCSDDMTLKIWSMKQEVCVHDLQAHSKEIYTIKWSPSGPATSNPNSKIMLASASFDSTVRLWDVERGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQNGNLVYSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK
Length568
PositionTail
OrganismCallithrix jacchus (White-tufted-ear marmoset)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Platyrrhini> Cebidae> Callitrichinae> Callithrix> Callithrix.
Aromaticity0.07
Grand average of hydropathy-0.377
Instability index38.64
Isoelectric point5.95
Molecular weight61879.37
Publications
PubMed=25243066

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-KW
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP32847
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             9|     399.62|      40|      40|     376|     415|       1
---------------------------------------------------------------------------
  219-  248 (32.74/13.41)	...............LRGHESEVFICAWNPVS.........dlL.A.SGS.GDSTAR
  249-  266 (24.83/ 8.64)	IW.NL.NEN..................................S.N.GCS.TQLVLR
  267-  302 (36.35/15.59)	HCiREG.GHD..VPS....NKDVTSLDWNTDG.........tlL.A.TGS.YD.GF.
  303-  345 (36.29/15.56)	.A.RIWTEDGnlASTLGQHKGPIFALKWNRKG..........nY.IlSAG.VDKTTI
  346-  386 (54.24/26.39)	IW.DAHTGEA..KQQFPFHSAPALDVDWQNN..........ttF.A.SCS.TDMCIH
  387-  428 (62.77/31.54)	VC.RLGCERP..VKTFQGHTNEVNAIKWDPSG.........ilL.A.SCS.DDMTLK
  429-  479 (57.16/28.15)	IW.SMKQEVC..VHDLQAHSKEIYTIKWSPSGpatsnpnskimL.A.SAS.FDSTVR
  483-  521 (50.32/24.02)	VE.RGVC.....IHTLTKHQEPVYSVAFSPDG..........kYlA.SGS.FDKCVH
  522-  563 (44.92/20.76)	IW.NTQNGNL..VYSYRG.TGGIFEVCWNARG........dkvG.A.SASdGSVCV.
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP32847 with Med16 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) AAASAATSTTAGVSQQNPPKNAQTPVNGEETRAHDINNHVKPMEVDGEVEIPSNKA
2) TELTGTSSRCCPRPARRGAMQSPVDHVQRLRGREGGSHSASTSSQRGEA
161
2
216
50

Molecular Recognition Features

MoRF SequenceStartStop
1) PRPARRG
13
19