Description | Mediator of RNA polymerase II transcription subunit 9 |
Sequence | MASNNSNNNNNSSTPNIKLEDIDFEFLPLIYDIIRSIEKELNEGSSVGQKAIHREQTEIPAKMQLLNDKFKKCREQLMKIEGIDITKEQQLKQLENLSKQLDMKRQLLTQYKNFSPIESSSQMHT |
Length | 125 |
Position | Middle |
Organism | Tetranychus urticae (Two-spotted spider mite) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Chelicerata> Arachnida> Acari> Acariformes> Trombidiformes> Prostigmata> Eleutherengona> Raphignathae> Tetranychoidea> Tetranychidae> Tetranychus. |
Aromaticity | 0.05 |
Grand average of hydropathy | -0.846 |
Instability index | 62.71 |
Isoelectric point | 6.13 |
Molecular weight | 14527.35 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364145 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP32819 No repeats found No repeats found |
MoRF Sequence | Start | Stop |
1) IHREQT 2) NSSTPNIKLEDIDFEFLPLIYDIIRSIEKELNE | 52 11 | 57 43 |
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