<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32806

Description Uncharacterized protein
SequenceMEREEKVLDIVLESLISRCDEIKKSLISFLYRLENEHQKLDWPAFLDNFALISGQINNLLKILKSEKTPPLRNRIFLPLLLSPDRDEDLAKLTEGRVVAFNHEMVPDYLRTKLEPEIESIEAKQIVKASTMNQEVGQKQITSINKIANTIIELVRTTKDEWESGSTQRSSIPVTSSIQDTNIILAAIYLGKGLKPSTITPKTEPRPGSIGPQIPGQSGPRPPGISKAPSAIKTNIKSASQGLLNLPGKFIKLSKCKNNKMVQFINYRMRVVLHDSRNLVGNFKAFDKHMNVILADCEEFRKIRGKGNRPDREEKRVLGFILVRGETIVSMTVEGPPPPEEGLPRVPVLGSIPGPGYGRAVGRGVPVPSVPLPTAAPGLQGPVRGVGGPSASIMTPQARGVPVAAAAAAVGATVGVPRPPVPIPGMPLGPVIPPGIPTPGVPGVPGVAGVPVVPGVPGVPGVPGVPGVPAPGIAPGIPAAQLAMGRGMPPTAPPGMRPPPPGMMRGPPPPGPPPGKLPPRPIENISFLFFVQFITMSPPPTREDRVKCYNARDTYWKCLDSNELISDPKSKIDCEQLRKTFTENCPQVWVFHFDRKYKYEKFKAEQAKENAKQMPYLAQDCFLVNGRDTIIGPFHTATFTPAEVKDLDKEGRVIVTGHQCRTKDGNELNLFIFNLYCPHNDPDRPERSIYKLSFHRLLEEVAHHILKADKSNHVLIIGDINISHQRIDHCDPADDFEESPHRAWLSEFLSPSEEYSSVHFIDIFRQRHPKARNAFTCWNTKNLARKTNFGTRIDFALCDDRFYKYVTDFEILTQVEGSDHCPIRVTFGDLQPLPSQQLPKICTKFWPELGQGKRQTSIKGFLMQTKAPQDEKTICTTVSKTLIKPNIKPNNKPNKKNKQDGIRKYFKTNEYDRSARDDDDSYGMMEPEIPSYDDQIVSCNDSERLNYENRDNKCLDDKEKKDNNAAKIWKMLLPGTVIAPLCSAHKEPCILLTVNKPGPNKGRKFYACSRPTGFKNDPASSCEFFKWYKS
Length1029
PositionHead
OrganismTetranychus urticae (Two-spotted spider mite)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Chelicerata> Arachnida> Acari> Acariformes> Trombidiformes> Prostigmata> Eleutherengona> Raphignathae> Tetranychoidea> Tetranychidae> Tetranychus.
Aromaticity0.07
Grand average of hydropathy-0.467
Instability index46.70
Isoelectric point9.11
Molecular weight114327.41
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
mitochondrion	GO:0005739	IEA:UniProtKB-KW
respiratory chain complex IV	GO:0045277	IEA:InterPro

GO - Biological Function
nuclease activity	GO:0004518	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
DNA repair	GO:0006281	IEA:UniProtKB-KW
mRNA processing	GO:0006397	IEA:UniProtKB-KW
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32806
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      94.72|      18|      18|     438|     455|       1
---------------------------------------------------------------------------
  212-  228 (28.58/ 7.87)	QIP.GQ..SG.PRPPGISKAP
  430-  450 (28.10/ 7.63)	VIPpGIptPGVPGVPGVAGVP
  451-  468 (38.04/12.65)	VVP.GV..PGVPGVPGVPGVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.69|      18|      18|     483|     500|       2
---------------------------------------------------------------------------
  483-  500 (46.06/17.45)	MGRGMPPTAPP.GMRPPPP
  502-  520 (37.64/12.94)	MMRGPPPPGPPpGKLPPRP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     129.23|      30|      30|     309|     338|       3
---------------------------------------------------------------------------
  309-  338 (52.64/25.28)	PDR...EEKRVLGFILVRGETIVSMT...........VEGPPPP
  352-  388 (39.30/17.15)	PGP...GYGRAVG....RGVPVPSVPlptaapglqgpVRGVGGP
  389-  418 (37.29/15.93)	SASimtPQAR..GVPVAAAAAAVGAT...........V.GVPRP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.67|      24|      30|     125|     154|       4
---------------------------------------------------------------------------
  125-  153 (29.01/38.47)	IVKAstmNQEVGQKQ.....ITSinKIANTIIEL
  156-  184 (35.66/21.47)	TTKD...EWESGSTQrssipVTS..SIQDTNIIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.31|      14|      30|     244|     257|       5
---------------------------------------------------------------------------
  244-  257 (26.01/17.11)	NLPGKFIKLSKCKN
  277-  290 (26.30/17.39)	NLVGNFKAFDKHMN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.25|      13|      30|     196|     210|       6
---------------------------------------------------------------------------
  196-  210 (19.38/18.76)	STItpKTEPRPGSIG
  229-  241 (21.87/12.42)	SAI..KTNIKSASQG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     197.48|      64|     642|      20|      86|       7
---------------------------------------------------------------------------
   20-   86 (100.69/73.53)	DEIKKSL..ISFlYRLENE..HQKLdwPAFLDNFALISGQIN.NLLKILKSEKTPPLR...NRIFLPLLLSPDRD
  682-  753 (96.79/59.46)	DRPERSIykLSF.HRLLEEvaHHIL..KADKSNHVLIIGDINiSHQRIDHCDPADDFEespHRAWLSEFLSPSEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.32|      35|     395|     535|     571|      10
---------------------------------------------------------------------------
  535-  571 (62.03/50.40)	MSPP.PTREDR.VKC.......YNARDTywKCLDSNELISDPKSKI
  924-  967 (51.30/32.89)	MEPEiPSYDDQiVSCndserlnYENRDN..KCLDDKEKKDNNAAKI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32806 with Med8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IAPGIPAAQLAMGRGMPPTAPPGMRPPPPGMMRGPPPPGPPPGKLP
2) PSTITPKTEPRPGSIGPQIPGQSGPRPPGISKAPSAI
3) PSVPLPTAAPGLQGPVRGVGGPSASIMTPQA
472
195
367
517
231
397










Molecular Recognition Features






MoRF SequenceStartStop




1) EFFKWYK
1022
1028