<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32806

Description Uncharacterized protein
SequenceMEREEKVLDIVLESLISRCDEIKKSLISFLYRLENEHQKLDWPAFLDNFALISGQINNLLKILKSEKTPPLRNRIFLPLLLSPDRDEDLAKLTEGRVVAFNHEMVPDYLRTKLEPEIESIEAKQIVKASTMNQEVGQKQITSINKIANTIIELVRTTKDEWESGSTQRSSIPVTSSIQDTNIILAAIYLGKGLKPSTITPKTEPRPGSIGPQIPGQSGPRPPGISKAPSAIKTNIKSASQGLLNLPGKFIKLSKCKNNKMVQFINYRMRVVLHDSRNLVGNFKAFDKHMNVILADCEEFRKIRGKGNRPDREEKRVLGFILVRGETIVSMTVEGPPPPEEGLPRVPVLGSIPGPGYGRAVGRGVPVPSVPLPTAAPGLQGPVRGVGGPSASIMTPQARGVPVAAAAAAVGATVGVPRPPVPIPGMPLGPVIPPGIPTPGVPGVPGVAGVPVVPGVPGVPGVPGVPGVPAPGIAPGIPAAQLAMGRGMPPTAPPGMRPPPPGMMRGPPPPGPPPGKLPPRPIENISFLFFVQFITMSPPPTREDRVKCYNARDTYWKCLDSNELISDPKSKIDCEQLRKTFTENCPQVWVFHFDRKYKYEKFKAEQAKENAKQMPYLAQDCFLVNGRDTIIGPFHTATFTPAEVKDLDKEGRVIVTGHQCRTKDGNELNLFIFNLYCPHNDPDRPERSIYKLSFHRLLEEVAHHILKADKSNHVLIIGDINISHQRIDHCDPADDFEESPHRAWLSEFLSPSEEYSSVHFIDIFRQRHPKARNAFTCWNTKNLARKTNFGTRIDFALCDDRFYKYVTDFEILTQVEGSDHCPIRVTFGDLQPLPSQQLPKICTKFWPELGQGKRQTSIKGFLMQTKAPQDEKTICTTVSKTLIKPNIKPNNKPNKKNKQDGIRKYFKTNEYDRSARDDDDSYGMMEPEIPSYDDQIVSCNDSERLNYENRDNKCLDDKEKKDNNAAKIWKMLLPGTVIAPLCSAHKEPCILLTVNKPGPNKGRKFYACSRPTGFKNDPASSCEFFKWYKS
Length1029
PositionHead
OrganismTetranychus urticae (Two-spotted spider mite)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Chelicerata> Arachnida> Acari> Acariformes> Trombidiformes> Prostigmata> Eleutherengona> Raphignathae> Tetranychoidea> Tetranychidae> Tetranychus.
Aromaticity0.07
Grand average of hydropathy-0.467
Instability index46.70
Isoelectric point9.11
Molecular weight114327.41
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
mitochondrion	GO:0005739	IEA:UniProtKB-KW
respiratory chain complex IV	GO:0045277	IEA:InterPro

GO - Biological Function
nuclease activity	GO:0004518	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
DNA repair	GO:0006281	IEA:UniProtKB-KW
mRNA processing	GO:0006397	IEA:UniProtKB-KW
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32806
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      94.72|      18|      18|     438|     455|       1
---------------------------------------------------------------------------
  212-  228 (28.58/ 7.87)	QIP.GQ..SG.PRPPGISKAP
  430-  450 (28.10/ 7.63)	VIPpGIptPGVPGVPGVAGVP
  451-  468 (38.04/12.65)	VVP.GV..PGVPGVPGVPGVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.69|      18|      18|     483|     500|       2
---------------------------------------------------------------------------
  483-  500 (46.06/17.45)	MGRGMPPTAPP.GMRPPPP
  502-  520 (37.64/12.94)	MMRGPPPPGPPpGKLPPRP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     129.23|      30|      30|     309|     338|       3
---------------------------------------------------------------------------
  309-  338 (52.64/25.28)	PDR...EEKRVLGFILVRGETIVSMT...........VEGPPPP
  352-  388 (39.30/17.15)	PGP...GYGRAVG....RGVPVPSVPlptaapglqgpVRGVGGP
  389-  418 (37.29/15.93)	SASimtPQAR..GVPVAAAAAAVGAT...........V.GVPRP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.67|      24|      30|     125|     154|       4
---------------------------------------------------------------------------
  125-  153 (29.01/38.47)	IVKAstmNQEVGQKQ.....ITSinKIANTIIEL
  156-  184 (35.66/21.47)	TTKD...EWESGSTQrssipVTS..SIQDTNIIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.31|      14|      30|     244|     257|       5
---------------------------------------------------------------------------
  244-  257 (26.01/17.11)	NLPGKFIKLSKCKN
  277-  290 (26.30/17.39)	NLVGNFKAFDKHMN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.25|      13|      30|     196|     210|       6
---------------------------------------------------------------------------
  196-  210 (19.38/18.76)	STItpKTEPRPGSIG
  229-  241 (21.87/12.42)	SAI..KTNIKSASQG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     197.48|      64|     642|      20|      86|       7
---------------------------------------------------------------------------
   20-   86 (100.69/73.53)	DEIKKSL..ISFlYRLENE..HQKLdwPAFLDNFALISGQIN.NLLKILKSEKTPPLR...NRIFLPLLLSPDRD
  682-  753 (96.79/59.46)	DRPERSIykLSF.HRLLEEvaHHIL..KADKSNHVLIIGDINiSHQRIDHCDPADDFEespHRAWLSEFLSPSEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.32|      35|     395|     535|     571|      10
---------------------------------------------------------------------------
  535-  571 (62.03/50.40)	MSPP.PTREDR.VKC.......YNARDTywKCLDSNELISDPKSKI
  924-  967 (51.30/32.89)	MEPEiPSYDDQiVSCndserlnYENRDN..KCLDDKEKKDNNAAKI
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32806 with Med8 domain of Kingdom Metazoa
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