<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32801
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MELVYSVTCASSSSSKRLNDWLVDRRCVSSLSNKNILAFTSFSDLTDSEPKYLSTHVYVIDLNLPHEPNLVTKHDEDVTILEWDSSGTRLLIGDAFGKIEIWSIKDFLINDWYLVNSFTAFGGEKTLSAVWFHNGIKSIIVTDKKDSSHSYSEKFINAKFNASVRQFGGKPANGFVAISASGLIWCAVYLSDNSIVTGTKILGNFRSKLKIVDICYTRNGEFLMITSNGSVDSSINCYRVSINLSYSNLGSDKTKCTITSQPFSSFYLNCSNDIVQANGYSYVNHIKFILKEAADAVIVGTSGSLGSTVELWVLRDKPVQLHKMYQQIKNSNGGSEFNNQSPKTTVWQYSCSVNYYQPIVAITTPRVSLYDVNPPLSYIMVSYRDNTVNCYIRENLKRIFAIGVNSISLQNNPSNKFGMVNVKSNSNPIISNIVDMQFSWSGTALALLDTNSQLFVYRIPPVTDPKASFNPVFLQTMLEYCLVSGNDWWDILICLRPTIIDSLCDMLTEGFMQRQTHALQQKYYNRFLAIKASLYRCLNQGNSGTSGQNKSGDCYTLFMLNSISHLLKSLLRPSVNADKEGPAEMLSNLIQTKGNDPIYFNVDKLLLCLEHKDFYVETVILQSLQQLNQWIGDLALFLLASLPQQFHNNYRFPGGGLIYDVKSLNTLRELLVIIRIWGLINESCLPNFVILSKDVDVIGQIFKLLSRMVATMGNEPDESFLDECCSLPNQVLITQMDLTLKARGVTSPAMFINPSPLQFQYFAEASFLKYHIKTHSVDGAVDNYKCTKMDTVRHIALGAKDSINGNIRMCTRCSAISLIQSQNKSPSTRTWDMRWCSNCICGGHWKVDNEY |
Length | 851 |
Position | Tail |
Organism | Tetranychus urticae (Two-spotted spider mite) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Chelicerata> Arachnida> Acari>
Acariformes> Trombidiformes> Prostigmata> Eleutherengona> Raphignathae>
Tetranychoidea> Tetranychidae> Tetranychus.
|
Aromaticity | 0.10 |
Grand average of hydropathy | -0.084 |
Instability index | 33.43 |
Isoelectric point | 7.88 |
Molecular weight | 95650.33 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | catalytic activity GO:0003824 IEA:InterPro
|
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP32801
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 85.66| 25| 109| 635| 662| 4
---------------------------------------------------------------------------
635- 662 (38.18/42.12) ALFLLASlPQQFHnnYRFPGGGLIYDVK
749- 773 (47.49/37.05) AMFINPS.PLQFQ..YFAEASFLKYHIK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 51.09| 14| 116| 584| 597| 6
---------------------------------------------------------------------------
584- 597 (25.72/17.85) EMLSNLIQTKGNDP
703- 716 (25.37/17.52) KLLSRMVATMGNEP
---------------------------------------------------------------------------
|