<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32789

Description Uncharacterized protein
SequenceMAGKVSSWLYEKRSLKKPKLGPSDVYPQEPKQKEDELTAINVKQGFITCPTIQEEYGSSRNANITPNKFGAFFSALLSKKQELNTLQDTGRRKPQINPKDNIWLVTQRSKPAVDTWFRDLASGTKTLAQLSRKVPIFNKKEEIFLQLYEFQVPMFKANWFIKMSSAYSIALSETANKSKKRQVIDQSQEWTGILCRFLRDLYQKICEHYHGGNTSSVAPSSFSNSVSPSSANINIDVVQKQWQYSCQLARSLFEEGLLDKQEFLNWMLDILEKIKTADDSVMRVVVTLILQYVEDFTESELCSRKLAYQCAIKLNQLVSSYNSVSSLNSSNNSNSSISSPGPNDSSSSITNGQTVNRSGSPTTSPTSNSTTSVEPLIISFRDLLSCPHHRNIAIGLSAIIQIITLKCPTAMVWHGDGRLSPALNGSPLDHLPCPPSVLPMPVRPHNRQLREELRVAEDEIRLRSRAVENKWCSDRSQQTAPGVIINRLLNTLDSLDCHSFEKVEPNNSIETLYSAIFKNQSSSIVKTDLSEKSLKKIIAEDEPIIKLLCEWAVTTKRTGEHRALVVTKLLEKRQNELLAEKENEKPEAKEMETNLPNGCKNSEATSLINETPHQIYQDLLMSFLDTQAPVWDDKNPNPESKLAFSNLVLLFGELIRCDVFSHDAYMCALISRGQFANSPNASSLIPPISDMKITNKSEQPSLTNFVPNLPSATILPSLGGPTSNLVGSIDVNTPNRSSESSLPMFEPVTDPSGSTRSDLIGNWEHLEMDDAQLDSDLGKLLQHIKEGQQNNMNDQTDILLPDSVSSDKEDEAGSILANMGFGQQESGPKVHVQRHLLYTTHFPLPQDETTNHDCNQRHVLLYGVGKARDDARHTVKKTTKEILKLFSRKSSMDISEGAKIKKKESFSFETALSKFQSLAYFDQHVVTSSCAVTCIEMFEGVANGTSAHLPLIEAIAFLFDLMEMALNIHGLIDFCIQLLKEMPDVEMKLNEKCPILVGNYCTQIGLYITGVLYRYQSCLLVSQEETVTIFEGLYKLVRNVSNPADCSSAERCILCYLYDLYTNCSHIKSKYFDLFNSIGQKIKQNIHTTREPSSVKLSWNTTCMSEYINNPKIKIDVNHLQQLNENAHFRYSFVCNAVHAVSTAKDANRLNDLSILCAELSSRCPALGSEWLGVLKALCCSYKQNSGFSEVLAQVNVSDISLHDNIAVFTCILIARRCFSPQDFVIHCALPSLLAASPTGGGCQDAEAGARLTCHILLCFFRSSEPPLSSNTVFITPATTLYSLTSPGPSNLPPPVSNIGHNRSSLFVIKHPCDRYLLAAANISMKVEAVLTILKAILVLGDSTDANRETKPKMENSSTKELNLNEFSGLMNDEEFNDYDFLLTGNKSKDKSDGVVEAAGLNEFAKHVLRQISSQEWILERCLRDPDVITKQDVFLDPSLTPEQALQLLQMICNPKSHTLVDQDFEPKQQITRVFQNLDEWTIRQSWLQLQLMYAQCCTAKSPTDVGNWLDMVAKATIDFFQQASEESSKNGLFHESGKVDKQSSEGQWQNKSTRVWLVSPLISKLPSSVQGKILKVAANVLESGNWMSAGSNSAQNSYSYSKNKDRGFSQQKSSSSGNANNPSSLLSYPPFLALVLMCLRGKDEQRESLLNSLFLQLQQAVHDRDDPKNRVINIQEGLQLRLSLVGGMFDMIQKSTSLINDWAVLFVQLISYGVVETQQSYELFTTVLDMLAVLIHTTQSSETSESREETRKQYQNLIKKLKKEFAFDKVGLGVDLIKQLLPISKQQCEVITCEPMGSLIDTKGNKIAGFDSIDKKQGLQVAEKQKVSPWDLLEGHKNPGPLSWSWFGAVRIERKPLRGEENHNILAWHTHSFKQPTSYYLEHPPLPPEDVIEPSPVPTPSILNDIKPQVVPPPIIPPQPTLIPMSIQEDPIKRERDTPVEVSSPRASTAKKPKATRRKRTPKNATAAAGAVVVNSMTPPLGPANVQTPPMRQMTNYDNYVQPGPPQPAPPQPAPPPQWYSQQQPGPQPPPPQAGPMHQQNQQFFHPAPMRTNTNHYDRAPLSKSKAMLQEAIKNRQQPPNVNQGYMSQNSGPPPNQGMVPGPVPVQVPGPVQIPGPVPVQVPGPGPLGPGPGVPPNQGPPPQHMYQSRQMMMPRPMRTRQPQPPPQPPPQMAMQPQNPMQTNQMYQMAPTNQMVPQNVNMPPNSMHHMPVQSQGNYGGPPPNMNYNNPMQMTGMDQQMGGHGINQGYAPPPTNQQNPAMMNPVMRQQLHPQAGHHPQGQPGPPMPPSQPQQQPPQQQHHPQQQYIQQGQMNSYW
Length2316
PositionKinase
OrganismTetranychus urticae (Two-spotted spider mite)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Chelicerata> Arachnida> Acari> Acariformes> Trombidiformes> Prostigmata> Eleutherengona> Raphignathae> Tetranychoidea> Tetranychidae> Tetranychus.
Aromaticity0.07
Grand average of hydropathy-0.474
Instability index55.17
Isoelectric point6.86
Molecular weight258075.75
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32789
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     642.47|      96|      97|    2004|    2100|       1
---------------------------------------------------------------------------
 1821- 1899 (104.62/50.05)	Q.VA.....EKQ.KVSP..WdllEGHKNPGPL...S....W..SWFGA....VRI..E...RK......PLRGEENH..........NILAWHTHSFKQPT......SYYLEHP.....PL.....PPEDVI.......ePSPvP
 1900- 2007 (105.93/50.79)	T.PSilndiKPQ.VVPPP.....II.......P..P....Q..PTLIP....MSI..Q...ED....PIKRERDTPVEVSSP.RASTAKKPKATRRKRTPKNATaaAGAVVVNSmtpplGPanvqtPPMRQMtnydnyvqPGP.P
 2008- 2106 (187.87/100.56)	Q.PA.....PPQ.PAPPPQW...YSQQQPGPQP..P....P..PQAGP....MHQ..Q...NQQFFHPAPMRTNTNHYDRAPlSKSKAMLQEAIKNRQQPPNVN..QGYMSQNS.....GP.....PPNQGM.......vPGPvP
 2108- 2163 (46.79/17.07)	QvPG.....PVQiPGPVP.......VQVPGPGPlgPgpgvP..PNQGPppqhMY...Q...SRQMMMPRPMRT......RQP...............................................................
 2164- 2212 (80.87/36.60)	...........................QPPPQP..P....P..Q........MAM..Q...PQN.....PMQTN.QMYQMAP............TNQMVPQNVN................M.....PPN.SM.......hHMP.V
 2213- 2267 (73.92/32.66)	Q.SQ.....GNY.GGPPPN....MNYNN...................P....MQMtgM...DQQ........................MGGHGI.........N..QGY..........AP.....PPTNQQ..npammnPVM.R
 2268- 2312 (42.48/14.63)	Q.QL.....HPQ.AGHHPQ.......GQPGPPM..P....PsqPQQQP....PQQ..QhhpQQQYIQQGQM..........................................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     217.32|      72|      97|     561|     642|       2
---------------------------------------------------------------------------
  561-  642 (108.91/83.34)	HRALVVTkLLEKRQnelLAEKENEK...PEAKEME.TNlpngckNSEATSLINETPHQIYQDLLMSFLDTQAPV...WDDKNPN..PESKL
  662-  742 (108.41/60.36)	HDAYMCA.LISRGQ...FANSPNASsliPPISDMKiTN......KSEQPSLTNFVPNLPSATILPSLGGPTSNLvgsIDVNTPNrsSESSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.15|      23|      97|     191|     232|       5
---------------------------------------------------------------------------
  209-  232 (37.88/ 7.99)	YHGGNTSSVAPSSFsNSVSP..SSAN
  308-  332 (36.26/16.28)	YQCAIKLNQLVSSY.NSVSSlnSSNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     107.41|      23|      98|     173|     206|       6
---------------------------------------------------------------------------
  181-  204 (42.25/38.54)	RQViDQSQEWTGILCRFLR..DLYQK
 1045- 1063 (31.84/14.41)	....DCSSAERCILC.YLY..DLYTN
 1410- 1431 (33.31/12.66)	RQI..SSQEW..ILERCLRdpDVITK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.52|      14|      97|    1636|    1649|      10
---------------------------------------------------------------------------
 1642- 1659 (15.30/ 7.54)	GKDEQRESllnsLFLQLQ
 1664- 1677 (20.22/13.10)	DRDDPKNR....VINIQE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.68|      13|      32|     778|     790|      11
---------------------------------------------------------------------------
  778-  790 (23.17/13.11)	GKLLQHIKEGQQN
  813-  825 (23.51/13.42)	GSILANMGFGQQE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.23|      12|     172|    1506|    1517|      19
---------------------------------------------------------------------------
 1506- 1517 (23.00/16.18)	VGNWLDMVAKAT
 1686- 1697 (23.23/16.41)	VGGMFDMIQKST
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32789 with Med12 domain of Kingdom Metazoa
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