<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32776

Description Uncharacterized protein
SequenceMASSEMSVGDRKIEDGKSEIILERLRNKASHMKPWTETIKAYRLALLDKRYTVDNADRLQMQKCLDTLQKSIKVTSLQAMVERLESITRQLRKRNFDDCSLKFTAGPNGTDCFISSDMFYVEVLLEMNGSVKDVKIAHHGDPVSCSELTQVLRAGDFTEFTSHLEGLTSIYQLNADKKQKSKAYLALQALETDLSMLAQLQSSINEPSNLVHKSPVGILQLRKGGHPMKLTYFISPYDLLDMETKSSIPLTVDTVVERQLGQYVTVCIESSTSHKLQTQSLMSITRTNDGKSLPSFAAPSNLNSTTLPANFVLKLASPMPIATALVKKIQAVTCIECADMSSSQPLLSLITQLASKGEMDCNNNKGLFVVLPDQHHCYFLNGAADLQGAMVSSIPFTHPTHVPQILVFLRQQMLFNVLISSCIRTGSKQDLETALMFEVTALSWLHVSVSFEHPLEESMATAEFDLSDITNVKCKLCTMGSDASICSDEYASKVVQRCLSIPVTMRAVIRKAQGQQKKANQSNEDIYVTMVTGNSGKFLSNAQNSTHNEGSNNQGGNNNAKFVSDFDVKLCRSGNRTSDSQSISKLDVLNTNVGSSSSSSYNMPSPDIATTPLGMDGQGYNESSPAHGDLFPLNSERASALILSGNHFGPPNSSQPSNLGKSGNSVTVTNTNQRQLVTLVSNAMGGHVKPRKERVKRKAVSEGNSPRSQTGRSPKQKHSEDDLVKDLSQSDVEVGNSSSMTTIPLGVDMELSVRQNIDPGLVKSTLEGMVKYEPMGSRAEINQHLMHRGSTSMHNESNAMDSDFFNSGNQNRSNEAEFNYKSEPMDFENEVYSNQNSTYDDGLMESGDEFNLEQLGINSSVLAAKIEKNKEAKKLKKLKLEIATKLGDKEQSGDGDAKSTPPPVIFDIISSQLKVVEPTKNACAVDLTEKRPNVEIIPIGNTSGSSSASLLTQGGLKIGLKSGESKLKQRDFRRGLVGDRSDKKSKGEGKRERKRKHLESLNSSDDKSGNKLLAVSITPVPLMTGSGVNVDKGMSIVSKSNEPTLPKSITLSVKSISASSSMSTSTAAITSKTVTTSCKKPQLPLSTTVSPTKSVSILKTPQSNKAKQGSIKPLGMVKSGQLGDSKTLSPSANKVTISPLKVHSGKAKSSSSKSLVSGSKPTTVRLKHLNIPSSTTVTPIIKASPTSTATTTLPSPTVTSPPVTFTALTAAASGVSTPTTPTSTAAMKMPALSVTTSVGFTNPTVTSTSATDSSSNGSGNATSGESGGGGNATKLSKSANRSRKGSLSAVIDKLRNSNRQSGSCDGQPAPSERKESKDGGGGSGGGGGEKKEAMKKESSHKDVGGAAKTGDKPKVGSGAEQKLSEKKPEFTVKQSSQGIKLTVTKTRSTESGGSKLSSSLKNSSSKLNASSNKSGTATTGGSSGGSVPKMTPSGGATGSKPGVGPASSKKLSGVSTSSKSPGGAVSAASGSSNSAVKPTVSKTPPLTSAGATFVSSATTKPISSATVKQSGGQKHGSADGKSVTSLSGTKMSERVQKSLSSTGHENSKAGGVLKLEKSSSLPNSMPPPPPPPIATDMGGQSRKSDDANRQRQSPKQSGSDETEAERQFRLLLAQTKMESNSGSTTTLTNSNLITKPTVTNSQPPLSSASGICSTAEKPEGSRTPKQELSDRSPKNNDGRSTPKTSTSGEKLFNFITNITNITSSMSSKTTPVVTMTTAVSEAKTMAAPVKASESGALKSTEVVNKCPGPASPPESASKVPNIFDHLKAVVKRQQNSPSNDDVSSPEDSLIIDYPGTPHHKSPEKKLKNVNVEQVVATGQTKSPTSPMVTTARSPAQPSPGIKSPMVIGTPHSDHSNPSSVARSSPCVIDDDLMDEALMGVGK
Length1882
PositionMiddle
OrganismStrigamia maritima (European centipede) (Geophilus maritimus)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Myriapoda> Chilopoda> Pleurostigmophora> Geophilomorpha> Linotaeniidae> Strigamia.
Aromaticity0.03
Grand average of hydropathy-0.527
Instability index47.98
Isoelectric point9.38
Molecular weight198810.49
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32776
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.13|      16|      16|     631|     646|       1
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  631-  646 (29.15/15.76)	F.PLNSERASALILSGN
  648-  664 (27.98/14.80)	FgPPNSSQPSNLGKSGN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     743.99|     146|     151|    1003|    1153|       2
---------------------------------------------------------------------------
  935- 1109 (182.22/69.12)	EIIPIG..NTSG.......SSS....ASLLTQ.........................GGLKIglKSGESK.....lkqrdfrrglvgdrsdkkskgegkrerkrkhleslnSSDDKSGNKllavSITP....VPLM........TGSG........VN..VDKGMSIVSKSNEPTLPKSITLSVKSISASSSMSTSTAAI.T.SKTVTTSCKKPQLPL..STTVS..PT..........KSVSI.LKTPQSNK.....AKQG
 1110- 1226 (155.03/56.34)	SIKPLGmVKSGQLGDSKTLSPS....ANKVTI.........................SPLKV..HSGKAKSSSSK.................................slvS.....GSK.......P....TTV..................................RLKHLNIPSSTT..VTPIIKASPTSTATTTL.P.SPTVTS....PPVTF..TALTA..AA..........SGVST.PTTPTSTA.....A...
 1227- 1350 (127.14/42.64)	.......MKMPALSVTTSVGFT....NPTVT.................................STSATDSSS.......................................................................NGSG.........N..ATSGES.GGGGNATKLSKSANRSRK.....GSLSAVIDKLrN.SNRQSGSCDGQPAPS..ERKES..KDggggsgggggEKKEA.MKKESSHKdvggaAKTG
 1351- 1516 (153.61/53.24)	D.KP....KVGS.GAEQKLSEK....KPEFTVkqssqgikltvtktrstesggsklsSSLKN..SSSKLNASSNK....................................SGTATTGGS....SGGS....VPKM........TPSGgatgskpgVGpaSSKKLSGVSTSSKS..PGG......AVSAASGSSNSAVKP.TvSKT.......PPLTSagATFVSsaTT..........KPISS.ATVKQSGG.....QKHG
 1622- 1740 (125.99/42.19)	.............GSTTTLTNSnlitKPTVT..............................N..SQPPLSSASGI....................................CSTAE...K.......PegsrTPKQelsdrspkNNDG.........R..STPKTS...TSGE.KLFNFIT.NITNI..TSSMS.........SKT.T.....PVVTM..TTAVS..EA..........KTMAApVKASESGA.....LKST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     129.48|      38|     180|    1563|    1605|       3
---------------------------------------------------------------------------
  573-  609 (43.97/16.84)	...SG.NRTSD.....SQSISKLDVLNTNVG.............SSSSSsynmPSPDIA
 1524- 1574 (58.35/26.28)	TSLSG.TKMSE...RVQKSLSSTGHENSKAGgvlklekssslpnSMPPP....PPPPIA
 1575- 1605 (27.16/16.85)	TDMGGqSRKSDdanRQRQSPKQSGSDETEAE............................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     390.41|     128|     152|     232|     383|       4
---------------------------------------------------------------------------
  241-  383 (208.93/142.16)	DMETKSSIPLTVDTVVE......RQ...LGQYVTVCIESSTSHKLQTQSLMSITRTNDGKSLPSFAAPsnLNSTTLPANFVLKlaspmpiatalvkKIQAVTCIEC...ADMS.SS........QPLLSL.ITQLA....SKGEMDCNN..NKGLFVVLPDQHHCYFLNGA
  387-  542 (181.48/89.67)	QGAMVSSIPFTHPTHVPqilvflRQqmlFNVLISSCIRTGSKQDLETALMFEVTALSWLHVSVSFEHP..LEESMATAEFDLS.............DITNVKCKLCtmgSDASiCSdeyaskvvQRCLSIpVTMRAvirkAQGQQKKANqsNEDIYVTMVTGNSGKFLSNA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.45|      29|      79|     744|     776|       5
---------------------------------------------------------------------------
  746-  776 (45.32/39.64)	GVDMELSVRQN..IDPGLVKSTLEgmVKYEPMG
  826-  856 (45.14/24.59)	DFENEVYSNQNstYDDGLMESGDE..FNLEQLG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     332.63|     109|     118|       5|     119|       6
---------------------------------------------------------------------------
    5-  119 (164.02/119.52)	EM..SVGDRKIEDGKSEIILERLrNKASHMKPWTETIKayRLALLDKRYTVdNADRLQMQKCLDTLQkSIKvTSLQAMVERLESI...TRQLRKRNFDDCSLKFTAGPNGTDCFISS.DMF
  126-  240 (168.61/100.96)	EMngSVKDVKIAHHGDPVSCSEL.TQVLRAGDFTEFTS..HLEGLTSIYQL.NADKKQKSKAYLALQ.ALE.TDLSMLAQLQSSInepSNLVHKSPVGILQLRKGGHPMKLTYFISPyDLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.64|      15|      17|    1822|    1838|       7
---------------------------------------------------------------------------
 1824- 1838 (28.19/15.41)	TSPMV..TTARSPAQPS
 1842- 1858 (25.45/ 7.01)	KSPMVigTPHSDHSNPS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32776 with Med1 domain of Kingdom Metazoa
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