<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32763
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MDLIYSVSRKFSLKSQSNSDWMHEGNAVCVISSRNTIAFTSRTKVDDSVGKSWRCHVYVADLNLPWDVYRALSHNEEITCLEWDTSGSRLLVADKIGQIQIWMMKDYLLNDWFCFSTSQFPGEHILCAAWFHNGKKIVLNNEKKDSPHYTDKFLTVRFGPSIRHTGGRPREGCIAIGATGMICVVLLSMDGTTSTSCDSLGLLRTRLKVVDLCYGKNGDFLIAASDGSMCSAVHCYKVTLKIQQNDSRSAQSDGKSFQDKCVISSQSLPGFYPSCFNTNASERSADKKITHLRFVVREAADAVVVCASGNAGSIIELWELREKQIILNKMFLNTSTDNKLKTVSWQHHASQPSPTQVVALTTPRTSLYDSNPPPSYILAAYRDNSIKCFYRESLQFVFSITINPSLLHREEAGGIKHVRIGTTISDMQLTWTGSTLIALDSLSQIYLYRLSPITDPGGPVSVSYAVALFEYCLITGIDWWDILLGLRAQFIDQVCEKLTDSFNRQLPSQQQYLFFRFLTLKMSLYRCLNSGQNKAGDCSALLMLNAVATAFKSMLRPADLSSQDRGPAENLTVIMSGKPVDNITDVMIHLENKEFIVESATLQSMQQLIQWVADFSLYLLASLPQQTHSLIHFPGCGLINDLKALNTLRELLVIITMWGFIKQSCLPTFTKTSDSLDVLALLFRLLSKALQCGEPDDSLLDECCLLPSQVLIPALTLGVEAKGVTSPALFQNSLPLPFEYCSEPPFMNYRMEVNVVEGAITTNQFYDNVRHTYLGCKPSQYKQCARCSCVSMLKNMPKSTATKAWDQRWARTCPCGGHWKLANG |
Length | 824 |
Position | Tail |
Organism | Strigamia maritima (European centipede) (Geophilus maritimus) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Myriapoda> Chilopoda>
Pleurostigmophora> Geophilomorpha> Linotaeniidae> Strigamia.
|
Aromaticity | 0.09 |
Grand average of hydropathy | -0.066 |
Instability index | 41.11 |
Isoelectric point | 7.83 |
Molecular weight | 92059.87 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
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GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | catalytic activity GO:0003824 IEA:InterPro
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GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP32763
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 57.56| 15| 19| 340| 357| 1
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340- 354 (29.10/21.92) LKTVSWQHHASQPSP
360- 374 (28.46/12.48) LTTPRTSLYDSNPPP
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 48.25| 13| 19| 498| 510| 2
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498- 510 (23.84/17.61) LTDSFNRQLPSQQ
520- 532 (24.42/18.25) LKMSLYRCLNSGQ
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 200.83| 64| 241| 124| 200| 3
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124- 200 (92.85/95.77) HILcAAWFHNGKKIVLnnekKDSPHYTdkfLTVRFGPSIRHtggRPREGCIA...IGATgmICVVLLSMDGTTSTSCDSL
376- 442 (107.97/69.46) YIL.AAYRDNSIKCFY....RESLQFV...FSITINPSLLH...REEAGGIKhvrIGTT..ISDMQLTWTGSTLIALDSL
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