<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32740

Description Uncharacterized protein
SequenceMDYEFKVKTANERAKVEDLFDYEGCKVGRGTYGHVYKARRKDGSDTKDYALKQIEGTGLSMSACREIALLRELRHANVITLIRVFLSHNDRKVWLLFDYAEHDLWHIIKFHRAAKANKKPVMVPKGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNCPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRKMPEHPTLLKDFKRSNYSNCSLVKYMDRHKIKPDTKAFHLLQKLLLMDPNKRILSEVAMQDPYFQEDPLPTQDVFAGCPIPYPKREFLTDDDQEDKSDKNNTRPNQTNNGGGGTGGGGDQTSGGHGGPNAKRVRLSGPPHPSQPPTNQANMQAQQQDFHHQHQQNMLFQSAGGQQQPNPNFPQRF
Length456
PositionKinase
OrganismRhodnius prolixus (Triatomid bug)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Paraneoptera> Hemiptera> Heteroptera> Panheteroptera> Cimicomorpha> Reduviidae> Triatominae> Rhodnius.
Aromaticity0.09
Grand average of hydropathy-0.681
Instability index42.68
Isoelectric point8.74
Molecular weight52288.98
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32740
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     119.66|      31|      35|     135|     165|       1
---------------------------------------------------------------------------
  102-  124 (17.95/ 6.64)	.........HDLWhiiKFH..RAAKANKKPVM..VP.
  135-  165 (58.42/36.92)	ILD.GIHYLHSNW...VLH..RDLKPANILVMGEGPE
  171-  203 (43.29/25.60)	IADmGFARLF.NC...PLKplADLDPVVVTFWYRAPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.58|      32|      40|     262|     298|       2
---------------------------------------------------------------------------
  241-  282 (43.10/34.93)	IKTSNpYHHDQLDRIFN.vmgfPQEKDWEDIRKMpehptLLKD
  283-  319 (51.48/28.94)	FKRSN.YSNCSLVKYMDrhkikPDTKAFHLLQKL.....LLMD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.51|      24|      33|     320|     343|       4
---------------------------------------------------------------------------
  320-  343 (42.28/24.53)	PNKRILSEVAMQDPYFQEDPLPTQ
  354-  377 (41.22/23.76)	PKREFLTDDDQEDKSDKNNTRPNQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32740 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IPYPKREFLTDDDQEDKSDKNNTRPNQTNNGGGGTGGGGDQTSGGHGGPNAKRVRLSGPPHPSQPPTNQANMQAQQQDFHHQHQQNMLFQSAGGQQQPNPNFPQRF
351
456










Molecular Recognition Features






MoRF SequenceStartStop




1) AKRVRLS
401
407