<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32738
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MDVLYTLRRKHIASNNDFIYSLHEGTSLCCISVKNIVAFTTRTELEDTLGKTYGSHVYVSDLNTPWHSHRVTSKSGTVLALEWDAPGERLLIATDGGDISIWTPREHVLNIWTCIGHSSFHGEAIIGAAFFHNGRKISIIAEKRDSVVYSEKMSHVKFSPSVRGFGGGAGEGCIVMTGTGMVGGILLPKEAGAKIITAAESLAATRVTLSIVDISYGKNGQFVVAVSNGDVCRVQCYRVSVKYADDRLHISSQALPSFFLQSFKSNGPGGKVTGLKFVTREDADSLVVCANTVHGGVVEVWQLTERPVSLHRVFQPPPDPFKTVAWQFECSYSTNSPITCVTTCKQALTTYAPPPSYVMIVTNDATLHCLYRDSLKLVGTRSIASAWQEDTIKHQRLSTKITHMDLTWLGCALALVDSHGQLYVVKVPPILEPGVGMTVNVASGLLEYCLVTGTDSWDVLVSIQLSIVDAITDRITDNFNRQPLSVQQFYYAGHLALRTSLARLTQNGQTKVADLTSLLMLHSVSTAFTSLLRPSDLSSHDKGPAESLAALLSDNLTDIDKVLLHLEGKEFTVEPSTLQSLQQLIQWTADLALNILARLPEQYKSTSVSCSELGRDIKAVNTLRQLLVIIRVWGLLRTTCLPMFVRSAENLDVLALLFKLLSKLVQTHEPDDTLIDDCCLLPSQVMIPQMNPSTPIVCIASPSFAYQSFPMQLEYGVEPEFLVFEPDQNILEGCLATDQNVDTLRHIYLGKQPYLVKQCCRCGGKAQVQVSTRTAPIRAWDQRWLRSCRCGGTWRIH |
Length | 797 |
Position | Tail |
Organism | Rhodnius prolixus (Triatomid bug) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota>
Neoptera> Paraneoptera> Hemiptera> Heteroptera> Panheteroptera>
Cimicomorpha> Reduviidae> Triatominae> Rhodnius.
|
Aromaticity | 0.08 |
Grand average of hydropathy | 0.039 |
Instability index | 32.88 |
Isoelectric point | 6.66 |
Molecular weight | 87820.92 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP32738
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 72.17| 19| 36| 314| 332| 2
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314- 332 (41.61/25.02) FQPPPDPFKTVA..WQFECSY
351- 371 (30.56/16.55) YAPPPSYVMIVTndATLHCLY
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 225.74| 65| 343| 199| 265| 3
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199- 265 (102.33/94.02) AESLAATrVTLSIVDIS....YGKNGQFVVAVSNgDVCRVQCYRVSVKY.ADDRLHISSQALPSFFLQSFKS
545- 605 (82.10/64.37) AESLAAL.LSDNLTDIDkvllHLEGKEFTVEPST.....LQSLQQLIQWtADLALNILAR.LP....EQYKS
677- 709 (41.31/27.14) ...................................DCCLLPS.QVMIPQ.MNPSTPIVCIASPSFAYQSF..
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 59.50| 18| 322| 410| 428| 4
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410- 428 (29.74/18.83) GCaLAL...VDSHGQLYVVKVP
733- 753 (29.77/14.77) GC.LATdqnVDTLRHIYLGKQP
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 59.25| 15| 16| 83| 97| 5
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83- 97 (27.81/17.44) WDAPGERLLIATDGG
102- 116 (31.44/20.66) WTPREHVLNIWTCIG
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