<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32736

Description Uncharacterized protein (Fragment)
SequenceAFSYEKRSLKRSRLGPPDVYPQEPKQKEDELTVANVKHGFASYPQLSDEFGSARNCNVSASKIGAYYSGILGIKEEINTLPDSGRKRQQINPKDNFWPATNRSKAAVEAWFKDLAGNKALLALSKKAPNFNKKEDIFPLLCDFQVPLLRAAWFIKLSSAYTVAVTEAKMKKRQLPDPTQEWTQTLLKFLKEQLLKLQEFYQSSTQTIMTDDQKLALKLWHYNIQLTRYLYQEGLVDRHELIQWTLDLLDRYKNLPTTEDGSLRLVIPVLLQYLEEFTQNELAARKLATVCVHRLALLCQGSASSSSATPAHGGVSPNSPNHNHTNANNSAAVTFNEYLNCPHHKDVILALSVIIQVITLECPTALVWNSLGEGKSTSVLNGSPLDHLPCTPTALPMPQRNANPHIRNQLRMAEEMIKQRSQAAENRWSCDKWQQTCAGVTKQRVLTALDALDRHSFYKVDTNNSLDTLYASIFPNPPEKPNYQVEKDEPIVNLLCWWAVSGVRYGEHRAIAVAKLLERRNNQVLQEPESSANGEDKDSVNSVAPGLPVFQPLLMKFLDHDAPVLDETNNSPANRTTFTNLVHLFSELVRHDVFSHDAYMCTLISRGDLLQINPQNGATTNPNSTPGRPPNSNKSIETPTTQIHLDSDPTALFDLKPNKLQEHGRAMEYDDSKIDDDLDKLLQTIKVEHQNSMDAPDSPKDVTGSLVSGGIGHVTGMDTNSDPHISADHRGKPSRHLLYSTHFPLPQDESCSHECNQRHVLLYGVGRVRDEARHLVKRTSKDICKLFSKKFSIDVAEGGKVKKHSRNEFNFESTTARVQNLSFFDQHVVTWQCSMTVLEMISSFASGNSNYLPVPEHVAFLFDLMELALNIYGLIDVCIQILKEIPEVEAQLTAKNSNLIRSYTTGLVLYIVGVLRRYHCCLLLSGEQTVAVFEGLCRVVKHISNPADCSSAERCVLSHLYDLYAACSLLKTRPHGAEPFSNAYPKIKAALYASQTPSQSGNQAATPFMADVVNGVRRHMKIEPAWVRQLNDSCSNRYSFVCNAIIGVCTTTDIDRLNDLGHLCAELTAMCNMLSSEWLGVLIALCVSTNSPSYLDIFRQVDIHNLTIHNSLAVFTSILVARHCFSLEDFVAHVALPSLLTVYNEGRGDADGDAEAGARLTCHLLLRLFKTSEVPQPGMYSVGTSPHPLPVSGSAGTSLRLSCDRHLLAAAHNNIKVGPVLAVLKAILVVGDVTAGRGNRGKVKPHKMTPPSGQGELSISHILGTSDFGTSASRDDLLMELSGTNVSNNGGLSELAQLVLKELCSEEWILERCLQKPEDLCTPEMMLDSMLTAKQAQRLLHMICYPDQPVPNDANLDQKAMITKILENLELWTLRVSWLDMQLMLKQFPTNSPDLNQWLENVAKAAINLFNLNSSSKEENSKSKSQSMWLVAPLVAKLPSCVQGRVLKVAGQVLESCNWFTSSSRSTTNKGGTPTRSSSAPQMGHHQPFLALVLTCLKGQDDQREGLLTSLHTQLTQCLQIAKEVWFYHHKSRNAMQDALLLRFSLIGGMFDTIQRNTTLSTDWAILLVQLVIYGVIDLNNNSELFNTVIDMLATLIHSTLDSQSEKCEENRKHYLNLMKKLKKEVGERNSPSIQFIKQLLPLPKKQTEVIACGHMGHFTDMKGNKIAFDSSDKHGLQVSEKFRISPWDILEGQKNPTPLSWSWFGAIRVERRFLPFEETHRLLQCHTHSQVKSPEYYLEPLPLPPEDIDPPKPMKGAGGGGPGGMHDSTPPSVDSPRGGKRTVGKQPLSARRKKQPKPGTPQVGGMQHVQVRDFKILYFYIITSRKLTNAPQMGQMVSGYGATTAGAQTNQASMFAGAPQPPPPQWEGYQSGPERRTNTAGQSANPTGPGRVNQSKQALQSMIRMRLAPSNQYMTQNQPQMQNFQPLQRQQMQQMQGMQGPPTTMQATQQSSQMFPAQQQQMYPNMQQQGMNQNYGGYGGEYQQRMRPPYMQQAPNVTMNSMGGPLSQSQPAPPYTRPGAPQNQQQQAQQVQQTQQ
Length2036
PositionKinase
OrganismRhodnius prolixus (Triatomid bug)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Paraneoptera> Hemiptera> Heteroptera> Panheteroptera> Cimicomorpha> Reduviidae> Triatominae> Rhodnius.
Aromaticity0.07
Grand average of hydropathy-0.419
Instability index47.35
Isoelectric point8.22
Molecular weight226785.72
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32736
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     104.16|      23|      23|    1916|    1938|       1
---------------------------------------------------------------------------
 1900- 1932 (36.48/17.29)	QSMIRMrlapsnqymtQNQP.QMQNFQ......PLQRQQM
 1933- 1962 (36.11/17.03)	QQMQGM..........QGPPtTMQATQqssqmfPAQQQQM
 2012- 2034 (31.56/13.85)	APPYTR..........PGAP.QNQQQQ......AQQVQQT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.67|      22|      23|    1744|    1766|       2
---------------------------------------------------------------------------
 1744- 1766 (43.22/31.15)	PPeDIDPPKPMKGAGGGGPGGMH
 1770- 1791 (38.45/22.36)	PP.SVDSPRGGKRTVGKQPLSAR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.79|      20|      23|     716|     738|       3
---------------------------------------------------------------------------
  716-  738 (29.45/26.82)	MDTNSDPhiSADHRGKpSRH.LLY
  742-  762 (37.34/20.98)	FPLPQDE..SCSHECN.QRHvLLY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     102.24|      21|      23|    1964|    1984|       4
---------------------------------------------------------------------------
 1860- 1876 (22.14/ 6.85)	....QPPPPQ.WEGYqSGPERR
 1964- 1984 (40.78/18.64)	PNMQQQGMNQNYGGY.GGEYQQ
 1988- 2008 (39.32/17.72)	PPYMQQAPNVTMNSM.GGPLSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.53|      16|      24|    1355|    1375|       6
---------------------------------------------------------------------------
 1368- 1390 (16.01/20.50)	LELWTLRVswldmQLMLKqfPTN
 1394- 1410 (23.52/13.27)	LNQWLENV....aKAAIN..LFN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.04|      20|      24|     645|     667|       7
---------------------------------------------------------------------------
  645-  667 (25.67/24.28)	DSDPTALfdLKPNKLqEHGRAME
  674-  693 (33.37/18.37)	DDDLDKL..LQTIKV.EHQNSMD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     128.75|      37|      98|     824|     863|       9
---------------------------------------------------------------------------
  824-  863 (63.03/42.99)	DQHVVTWQCSMTVLEMISSFASGNSNYLPVPEHvafLFDL
  926-  962 (65.72/37.63)	EQTVAVFEGLCRVVKHISNPADCSSAERCVLSH...LYDL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.43|      12|      98|     885|     917|      11
---------------------------------------------------------------------------
  871-  882 (21.63/33.57)	Y..GLIDVCIQILK
  902-  915 (15.79/ 7.86)	YttGLVLYIVGVLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.13|      20|      23|    1532|    1554|      13
---------------------------------------------------------------------------
 1532- 1551 (36.23/30.76)	RNAM..QD.ALLLRFSLIGGMFD
 1555- 1577 (24.90/10.48)	RNTTlsTDwAILLVQLVIYGVID
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.56|      11|      26|    1208|    1218|      20
---------------------------------------------------------------------------
 1208- 1218 (20.05/10.69)	AAAHNNIKVGP
 1234- 1244 (20.51/11.09)	AGRGNRGKVKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.86|      17|      22|    1314|    1333|      22
---------------------------------------------------------------------------
 1314- 1333 (25.98/19.51)	QKpedL....CTPEMML..DSMLTAK
 1336- 1358 (20.88/ 7.87)	QR...LlhmiCYPDQPVpnDANLDQK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32736 with Med12 domain of Kingdom Metazoa
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