<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32730

Description Uncharacterized protein
SequenceMDREKLEILSFIEKEKKIVTTRLGRDINELRRKTRNESLAKRAKDLVRRWRDLILPQSEPPSADATHQNGASRQVVLPSRTVRTHPISPATSLPNSDKSSISPALSTRVEAVPRTHAANKRLRKEVQPPVPNEVKRSSESSPELPSKRVKLETQSLEPQDIKPRVNGDHYDSVGSDCDIVTFTSTLPKQKIRKKAPKDRTNKEPTTADDIVKEKIALIARVPKVKTTQELLAGLQSRSNETPDECIHPVVDHDVVKNKTEHIARFLRSQAENVEEIDEGRSPQESDNHSVAESEVEPQLQEIPKDPQPELRTADEILSRLPPLDLDAIKWDDTPVPSPELKEITEEDVDRVLNQHIEGINGNYDDSSEIRVFREWHEVVSRTSFDSELIHILPYVVID
Length398
PositionUnknown
OrganismRhodnius prolixus (Triatomid bug)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Paraneoptera> Hemiptera> Heteroptera> Panheteroptera> Cimicomorpha> Reduviidae> Triatominae> Rhodnius.
Aromaticity0.03
Grand average of hydropathy-0.835
Instability index76.99
Isoelectric point5.79
Molecular weight45151.14
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32730
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.55|      34|      38|      73|     110|       1
---------------------------------------------------------------------------
   73-  110 (46.33/34.65)	RQVVLPSRtVRtHPISPatSLPNSDK..SSISPAL.STRVE
  114-  150 (47.22/22.64)	RTHAANKR.LR.KEVQP..PVPNEVKrsSESSPELpSKRVK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     142.12|      39|      39|     267|     305|       2
---------------------------------------------------------------------------
  237-  265 (23.41/ 7.31)	.............RSNETPDEciHPVVDHDvV.KNKTEHIARF
  267-  305 (62.14/30.04)	RSQAENVEEIDEGRSPQESDN..HSVAESE.V.EPQLQEIPKD
  307-  346 (56.57/26.78)	QPELRTADEILSRLPPLDLDA..IKWDDTP.VpSPELKEITEE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32730 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LRSQAENVEEIDEGRSPQESDNHSVAESEVEPQLQEIPKDPQPELRTADEI
2) STLPKQKIRKKAPKDRTNKEPTTADDIVKEK
3) WRDLILPQSEPPSADATHQNGASRQVVLPSRTVRTHPISPATSLPNSDKSSISPALSTRVEAVPRTHAANKRLRKEVQPPVPNEVKRSSESSPELPSKRVKLETQSLEPQDIKPRVNGDHY
266
184
50
316
214
170










Molecular Recognition Features






MoRF SequenceStartStop




1) KQKIRKKA
2) KRAKDLVRRWRDLILPQ
3) NKRLR
188
41
119
195
57
123