<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32721
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | PLFVRVSINNVVAFISSYELISCNSSNKDLKRDKSKPFCNVYVCDIVSPWNVFLVTRKTMPITILEWDPSGEHLLIGDTQGRLEIWGKINHLLSDWNQLHYVNLPGETIIQAEFFHSGRTMTIAFDKRDNNQYMEKFQNVKYIPSVRKFGGIAENGCLVVTSTGLLGAFLIPYNNSSSTAASAPTELLPVTETLGLVRNFVTTAAISYAKIPNRSGYFRVAVTNTEMKSDFMVHCFRVELSLVNNKLSISSKSLPAFFGTESNDQRKITKLKWMITNDFDSLIVTENLSSTCVTNMWTLTHKPITIHKYLQTAGKTDVFKHYSWTNQFQYESQANVVAVTLTKNPFDNVFVYLLMNDNTIHILRRDLKLVSTTNYSIVENIFKMEHIGKIPRIDKQLVALDITFMSHLLVTVDNLGDICTFKVPQFYTEQCSNQMQLVNYKTTLLEYCLVTGYDASDVLMTMKPNYIENVLEKMSDNFSRQNSSTQQFYYVNSLTMKTNLARLLPNGQMRVNDLSSLIMLHSILVAFKSLLRPSELTNYEKGPSESLAMVLSESNPDIDKVLMNLDAKDFTLESSILPSLQQLIQWVADLALNILTRLPLDNFKSTNINKSTDYDICKDIVALNSIRELLVLGTSRQKLSSVFTKSAENIDILVTLFRLLTKLSFNPSEPDEVLVDDCCSLPTQVVIPPSVTNSINSPSLTLHLHPQQFQYNIEPDFLRYSRQNILEDNNNDVFMDGISHYVMGKNPQSMKHCLRCGTSTYIKNLAKTVAMNAWEHRWSSGCICGGQWTLLKN |
Length | 793 |
Position | Tail |
Organism | Megaselia scalaris (Humpbacked fly) (Phora scalaris) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota>
Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Platypezoidea>
Phoridae> Megaseliini> Megaselia.
|
Aromaticity | 0.09 |
Grand average of hydropathy | -0.113 |
Instability index | 36.89 |
Isoelectric point | 7.09 |
Molecular weight | 90009.42 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP32721
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 421.75| 110| 123| 236| 358| 1
---------------------------------------------------------------------------
236- 331 (143.67/98.54) ...............................FRVELSLVnnkLSISSKSL.PAFFGTESNDQRKI..TKL.KWMITND..FDS..LIVTENLSSTCVTNMWT..................................LTHKPITIHKYLQTAGKTDVF.KHYSWTNQFQYE
341- 490 (123.80/71.99) LTKNPFDNvFVYLLMNDN.........tihiLRRDLKLV....STTNYSIvENIFKMEHIG..KI..PRIdKQLVALDitFMShlLVTVDNLGDICTFKVPQfyteqcsnqmqlvnykttlleyclvtgydasdvlMTMKPNYIENVLEKMS..DNFsRQNSSTQQFYY.
595- 712 (154.27/84.87) LTRLPLDN.FKSTNINKStdydickdivalnSIREL.LV...LGTSRQKL.SSVF.TKSAENIDIlvTLF.RLLTKLS..FNP..SEPDEVLVDDCCS.LPT..................................QVVIPPSVTNSINSPSLT.LH.LH...PQQFQYN
---------------------------------------------------------------------------
|