<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32717

Description Uncharacterized protein
SequenceMVDENGDPKCSSKICWGGKVPEELFTKQNDDNVNNKNFQEAVVNKGQKLKIELDTKDEENQILAWEFRTFDYDIKFGIYSLDLKTGEKTSEVHLGNVHSHEMDEIGFITCRPQTKYDTIPSPLRRVLSVSVRSQAKGTNQHRNWIVEFVFFSTPLQSSNHREQGNRRTVYLTYEQSPSEMTRTVDDFLRDWSRIVFLYMLVYKFAEDFKNERYNLHNIVTIKSFNYTSLTFGYGPNKEITCNITWDAESKGFKMTFIGGKPQFPALSFTILPQSPTLLRLAYHSNYCLEIRLKSNGLVSIRDGAYSRFNQSTVIQEFTPTQNLKGFLTKYVDENAFYRRRSQSEDDNPPSPITMEESHPIGPGGSSPFISNALRGSQSPRDGGLRFPTPHTPPSSTNNPHTPPTHPNFNMTSPPAPHMPLPSPNNIMPSSPLNPQPSPMSMAHSPGPNSLPYMQQHGTEGSPFPALSPAASNWPGSPSIPRPSPRPGQSPDHKSQSAANTNTSGQTTTHINRVLPAKAWAGAVPTILSHEALETMCRPNKDIPGMEISPLERFLGCCYMRRSLQKHFQDDREGIIKT
Length577
PositionTail
OrganismMegaselia scalaris (Humpbacked fly) (Phora scalaris)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Platypezoidea> Phoridae> Megaseliini> Megaselia.
Aromaticity0.09
Grand average of hydropathy-0.695
Instability index66.70
Isoelectric point8.28
Molecular weight64970.27
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32717
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     162.83|      38|      43|     406|     445|       1
---------------------------------------------------------------------------
  387-  402 (27.36/ 6.88)	...........PTPHTPPSSTNN.....P...........HTP
  406-  445 (70.61/34.81)	P...NFNMTSPPAPHMPLPSPNNiMPSSPLNPQPSPMSmAHSP
  451-  490 (64.86/25.72)	PymqQHGTEGSPFPALS.PAASN.WPGSPSIPRPSPRP.GQSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.04|      17|      28|      23|      39|       2
---------------------------------------------------------------------------
   23-   39 (29.54/24.05)	ELFTKQNDDNVNNKNFQ
   52-   68 (29.49/23.99)	ELDTKDEENQILAWEFR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     227.46|      53|     152|      70|     125|       3
---------------------------------------------------------------------------
   70-  122 (95.61/58.81)	FDY.DIKFGIYS.LDLKT..GEKTSEVHL.GNVHSHEMDEIGFITCRPQ...TKYDTIP.SP
  224-  275 (62.85/34.65)	FNYtSLTFG.YG....PN..KEITCNITWdAESKGFKM...TFIGGKPQfpaLSFTILPqSP
  300-  351 (69.01/41.85)	.....IRDGAYSrFNQSTviQEFTPTQNL.KGFLTKYVDENAFYRRRSQ...SEDDNPP.SP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32717 with Med14 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AFYRRRSQSEDDNPPSPITMEESHPIGPGGSSPFISNALRGSQSPRDGGLRFPTPHTPPSSTNNPHTPPTHPNFNMTSPPAPHMPLPSPNNIMPSSPLNPQPSPMSMAHSPGPNSLPYMQQHGTEGSPFPALSPAASNWPGSPSIPRPSPRPGQSPDHKSQSAANTNTSGQTTTHINRVLP
335
515










Molecular Recognition Features






MoRF SequenceStartStop




NANANA