<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32701

Description Uncharacterized protein
SequenceMDYEFKARLASERSKVEDQFEFEGRKVGRGTYGHVYKAISKDSSETREYALKQIEGSGISMSACREIALLRELHHPNVIALKKVFLSHSDRKVCLLFDYAEHDLWHIIKFHRSAKVNKKIVNVPKNMIKSLLYQILGGIHYLHSHWVLHRDLKPANILVMGEGPDRGKVKIADLGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPLDRDWEDMKKMPEHQTLMKDFKRNNYMSCTLAKYMEKHKIRSDSSAFYLLQKMLTMDPTKRISSDEAMRDNYFREDPLPSQDVFENMPIPYPKREFLTDDETEEKSDNTASKVNYYYSCCLLLFLLFIAIIIVHCYYYYYKYYK
Length406
PositionKinase
OrganismHelobdella robusta (Californian leech)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Annelida> Clitellata> Hirudinea> Rhynchobdellida> Glossiphoniidae> Helobdella.
Aromaticity0.12
Grand average of hydropathy-0.404
Instability index48.72
Isoelectric point8.40
Molecular weight47777.65
Publications
PubMed=23254933

Function

Annotated function
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IBA:GO_Central
RNA polymerase II CTD heptapeptide repeat kinase activity	GO:0008353	IBA:GO_Central
GO - Biological Process
protein phosphorylation	GO:0006468	IBA:GO_Central

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP32701
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     117.65|      26|      40|     310|     335|       1
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  270-  289 (29.40/16.41)	..MKKM....PEHQTLMKDFKRNNYM
  310-  335 (45.81/29.24)	YLLQKMLTMDPTKRISSDEAMRDNYF
  353-  378 (42.44/26.61)	YPKREFLTDDETEEKSDNTASKVNYY
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP32701 with CDK8 domain of Kingdom Metazoa

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