<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32690

Description Uncharacterized protein
SequenceMAGNFWHSSHYQQWLLERSDLLRERHEDLSVLTAEEYQKIIIFFANVIQVMGENLKMRQQVIATATIYFKRFYARNSFKCIDPLLVAPTALFLASKVEEFGVVTNTKLTACCAHILKTKFSYAYSTDFPYRMHQILECEFFLLETMDCCLILYHPYRSLTQYMQDLNNDEQLMQMAWRIINDSLRTDVSLLYPPYLISLASLHLASIILNKDLKQWFAELSVDLDKLLEITKELLALYDLWKTFDEKKEVPALLAKMPKPKVNPSRPSSQGANSQQQQQQQQQQQDMNVQQQQQQSNQLMSNVQ
Length304
PositionKinase
OrganismHelobdella robusta (Californian leech)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Annelida> Clitellata> Hirudinea> Rhynchobdellida> Glossiphoniidae> Helobdella.
Aromaticity0.11
Grand average of hydropathy-0.278
Instability index59.54
Isoelectric point6.18
Molecular weight35596.63
Publications
PubMed=23254933

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IBA:GO_Central

GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32690
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.87|      34|      36|     121|     156|       1
---------------------------------------------------------------------------
  111-  146 (52.37/28.39)	CCAhILKTKF.SYA.YSTDFPYRmHQILECEFFLL.ETM
  148-  184 (51.50/27.87)	CCL.ILYHPYrSLTqYMQDLNND.EQLMQMAWRIInDSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.24|      15|      15|     223|     237|       2
---------------------------------------------------------------------------
  223-  237 (23.64/15.67)	DLDKLLEITKELLAL
  239-  253 (27.60/19.33)	DLWKTFDEKKEVPAL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32690 with CycC domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ALLAKMPKPKVNPSRPSSQGANSQQQQQQQQQQQDMNVQQQQQQSNQLMSNVQ
252
304










Molecular Recognition Features






MoRF SequenceStartStop




1) AKMPKPKVNPSRP
2) QQQQQDMNV
255
281
267
289