<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32680

Description Uncharacterized protein
SequenceMNLSAIIHAIMLSCPGALVWHNLGEGKMSHSLSGSPLDFLPCPPSTLPMPAAKENINIRLILRSIEDEIVHRSEMSSSKWSVDKQKLSNAGWLLFRILPCLEILDKHNFDRVESASSFDTLYNKIFSAASSKDGNNSGPSINKLVINFLCEWAVTTKRTGLHRITVVAKLLEKYQNNLSNEKSSENETSDDKDTDTLPPSSSSSHPPFQNILFDFLDNKAPYLTEASSNEMKGSFANLVMLFSELIRQELFSHDTYVCCLIARGELSNATSILQSIQYLHVPDDGNSSSSSSSNVAGNNSSGGQQQIQQQHTPQHHQSQQQSNVLQHSNSQQNFQQQQSQQQQQSVSANTVTAAKPFGREIRHILYVLHFPVTSSEPCSHENNQRAVVLCGFGRAREEMKHTIKRITKDISKLFGKKNCLDVVTGEVNNKVKKKKEKDVTTDPAICLDNLFNKFQRLSYHSQHLVTNCIVKSLTDAMQSFATGNTQLLPSVENISFLFDLIESCDNIFLLLNLVNKLLTDIPEIEVQLVSKGSVLAGSYSTNLCMCIVGVLRVHHATLLLFHDHTATVFDCLCRVVKHVDKPSECTSAERCILAYLYDLYTSCCIVKTKFSDMFAGPCAKVKITLFSDIVPSTSNLVWEDKPYSKELAENPKFDLFVFDSTFIKLLSDEPNDRYGFVCNMMATIFNSQNVDRVNDLSILCAELTAQCNVLSSDWLGVLKALCWSSNHNCGFLDILTQCDVSDISVHDSLAVFVAILIAHHCFSLEELIGQVALQSLLAACPTVGSGGDPECEPGARLTCHLLMRIFQMMSGTHGSSGASRCGTPNMYIKLSRDRRLIEASTRRITVGAVVAVLKAILMLGNYPVESSSITKPSSVLKKSTSFLESILEGSPEMPKNLPKSKENAGMSGFAKHCLKEMCSQAWVREKFLREPELLLTSDLLLDRMLSQKQACQLVQMICYHDDDNDDEDEEANLMSKNISRILRNMDEWMMRVSLLELQLMVKQASPSELPTLLESIAKGTIDVFQQQSKVVKQQSLCQLSPAGTSSQDDSAVLSASKGSKQADSVWFITPLITKLSGAIQGKILKTAGSVLETGNNFWTAKNSKDKEKYLKKSSSLLGNQPFLGLVLSCLKGQDEQREFLLKSLHDQFEKFIASAKEQQERAVPADETLQNMLQEALQLRLSLVGNMFDTIQRNNNLIQDWSLLLVQLICCSVVDMQNNSDLLSTLLDMLAVLIHGTQAFEGQDKGDENKKLYQNLIRKLKKELGEKKSMSIDLLKQLLPLSKVYNEVIVSEFQQGSDPKNNKTTEGEKSQCLQVTRKERVSPWDILEGQRTSTLLSLSWFGAIKREKKLLKYEEQHRLLLHHTHTIKKPDTYFLEPPVLPPDEEVHQEKPLSSPQQPEIKPMEQMVEVKQEVTKSSKKNSRSRVNKKQPVSRPPIPQQPSMPHYVNQGAPQPPSMSFNRPEMYTPSMPVQNWYNNQQYPNQMVQGGPPAGRSYPPSVAPTPPNLPNPRQMLNNVLKTRHPMQQQQQPQPQQQFMNTSQQQQQQQQQQQQQQMVWSRQRAPLARGTRMSMYPTQQQSQTQPVQQAQQQAAAAQLSGQHFPGQGYPGYPTQNLPSQMEQAAAVPMNTAYPPQQQPQPQQPQAPSNMGYVAANQQVPPQGQYPTAAARYANMPLAGGSGLPGYNQMIRQANNPQATGFVAASASMQTPHQQQQQKYLRQQMFLQQQQQQQLASQQRQQNMPFNNFQ
Length1744
PositionKinase
OrganismHelobdella robusta (Californian leech)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Annelida> Clitellata> Hirudinea> Rhynchobdellida> Glossiphoniidae> Helobdella.
Aromaticity0.06
Grand average of hydropathy-0.439
Instability index55.34
Isoelectric point7.85
Molecular weight195228.31
Publications
PubMed=23254933

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coactivator activity	GO:0003713	IBA:GO_Central

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32680
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      85.83|      18|      21|    1520|    1540|       1
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 1520- 1535 (31.08/ 7.60)	......HPMQQQQQPQPQQQFM
 1536- 1553 (22.06/ 6.98)	NTsqqqQ...QQQQQQQQQQ.M
 1625- 1643 (32.70/ 8.90)	NT...aYPPQQQPQPQQPQAPS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     155.35|      24|      26|    1429|    1452|       2
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 1432- 1454 (36.85/15.50)	S....RP..............PIPQQPSMP...HYVN.QGAP..qPP
 1455- 1484 (31.34/12.04)	SmsfnRP..............EM.YTPSMPvqnWYNN.QQYPNQ.MV
 1485- 1501 (23.75/ 7.27)	Q....GG..............P.PAGRSYP...PSV........aPT
 1558- 1582 (35.91/14.91)	Q....RA..............PLARGTRMS...MYPTqQQSQTQ.PV
 1583- 1617 (27.51/ 9.63)	Q....QAqqqaaaaqlsgqhfP...GQGYP...GYPT.QNLPSQ.ME
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      70.01|      18|      21|     671|     691|       3
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  650-  664 (19.43/10.13)	NPKFDlFV.......FDSTFIK
  671-  691 (28.57/30.01)	NDRYG.FVCnmmATIFNSQNVD
  694-  709 (22.02/12.61)	ND.LS.ILC...AELTAQCNV.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      74.66|      20|      22|    1666|    1687|       4
---------------------------------------------------------------------------
  287-  317 (28.19/11.62)	SSSssssnvagnnsSGGQQQIQQ..QHTPQHHQ
 1676- 1695 (33.97/15.66)	SGL...........PGYNQMIRQ..ANNPQATG
 1701- 1716 (12.50/ 6.64)	ASM...........QTPHQQQQQkyLR......
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.51|      20|      22|    1376|    1397|       5
---------------------------------------------------------------------------
 1377- 1396 (37.93/19.56)	PPVLPPDE..EVHQEKPLSSPQ
 1398- 1419 (29.58/13.34)	PEIKPMEQmvEVKQEVTKSSKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.12|      10|      21|     351|     360|       6
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  351-  360 (18.28/ 9.43)	VTAAKPFGRE
  372-  381 (17.84/ 9.02)	VTSSEPCSHE
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.47|      18|      22|    1167|    1184|       7
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 1167- 1184 (29.23/17.32)	ETLQ...NMLQEALQLRLSLV
 1189- 1209 (24.23/12.98)	DTIQrnnNLIQDWSLLLVQLI
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.16|      23|      27|    1084|    1110|       9
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 1085- 1109 (35.09/19.71)	KTAGSVLetGNNFWTA......KNSKDKEKY
 1111- 1139 (33.07/18.29)	KKSSSLL..GNQPFLGlvlsclKGQDEQREF
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.05|      10|      27|     782|     791|      10
---------------------------------------------------------------------------
  782-  791 (20.85/10.92)	TVGSGGDPEC
  812-  821 (20.21/10.37)	THGSSGASRC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.77|      27|      27|     998|    1024|      11
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  983- 1009 (45.79/27.57)	RNMDEWMMRVSLLELQL...MVKQASPSEL
 1010- 1039 (37.99/21.57)	PTLLESIAKGTIDVFQQqskVVKQQSLCQL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.49|      18|      22|     484|     502|      13
---------------------------------------------------------------------------
  484-  502 (26.85/21.41)	NTQLLPSVENiSFLFDL..IE
  506-  525 (24.64/14.19)	NIFLLLNLVN.KLLTDIpeIE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      30.86|       8|      26|     544|     555|      14
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  544-  555 (13.35/17.05)	CMCIVgvlrVHH
  571-  578 (17.52/ 9.13)	CLCRV....VKH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     333.62|     105|     149|      22|     135|      15
---------------------------------------------------------------------------
   22-  135 (161.78/114.18)	NLGEGKMSHSLSGSPLDFLPCPPSTLPMPAAKENInirlILRSIEDEIVHRSEMSSSKWsvdKQKLSNAgWLLFRILPCLEILDKHNF.....DRVEsASSFDTLYNKIFSAASSKDGN
  177-  286 (171.84/98.43)	NLSNEKSSENETSDDKDTDTLPPSSSSSHPPFQNI....LFDFLDNKAPYLTEASSNEM...KGSFANL.VMLFSELIRQELFSHDTYvccliARGE.LSNATSILQSIQYLHVPDDGN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.05|      11|     150|     758|     770|      17
---------------------------------------------------------------------------
  758-  770 (17.16/18.76)	AHHCfsLEELIGQ
  910-  920 (22.89/15.51)	AKHC..LKEMCSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.29|      17|      26|    1315|    1338|      18
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 1315- 1336 (19.74/27.54)	VTRKERVSPWDilEGQRtstLL
 1344- 1360 (27.55/11.89)	IKREKKLLKYE..EQHR...LL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.26|      14|      26|     837|     854|      19
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  837-  854 (12.90/22.09)	IEASTrrITVGAvvAVLK
  864-  877 (23.36/16.02)	VESSS..ITKPS..SVLK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32680 with Med12 domain of Kingdom Metazoa
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