<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32679

Description Uncharacterized protein
SequenceMVLLDNQKVYDVAIVVEATSGAADYYETMRTSYLLPILEFFNGHSIDEPVYGYCCNSSLYSLITYKGNDHPFSNMSTCSSPTYNCHEFAQTLNQISFSGGMLDPHSFIAEGLATALSLFEDIDLIRKNRVKAEKHLILYCSNGPYQFPCLGHYKYLNKTTEQLVNLLAESNIHFSIISTRKIHSLVKLFELGQPDPSCLTKNYASDSTHLVLLNDINITECPLSPSAKSSDESNMAVKPATTIPAPKSVCISIVRPQQGMSQNISANKEAVETFSIRPVANLSAVPQQQQQMSVQAPNSVAPVHPLTFTGSPATPTAIALRRAAVNQQQQQQQATMQVGGYQASLDPQSQLMQQQQMQQQQMQQQQMQQQQMQQIQQMPQNHLQQQQSDSLLQQQQQQQQQQQQQQTQSNNLTNVDINNPGPTLALAAQQQQQQQQQIQQQQRIIWTGPLEWTDKLKNQSVKITRTLPCQININQDEPEINTSKWPEKLTMSIFPPSVIQPLQHLFRSSRTVLFNFNQNSDTEAMNSLYRSLSNNFSGCIHFSTTPETSNDIKVLMLLYSNRKQQFLGLIPYDQANFLKSIKSVIAKHKVMKPQNPGEMVGTSAQSINQPTLQHQQITYQQNMQDPRQQHMLAIQQQQQLQQQQLQQQQLQQQQQMQQQHLQQQQMQQQQQMQQQRMQQMPQMHIQSNSQPLRYLLLNQQRPQHHMMNRPRGPATTLQQQQQPGVQTFTTMATDDFPPFDL
Length741
PositionUnknown
OrganismHelobdella robusta (Californian leech)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Annelida> Clitellata> Hirudinea> Rhynchobdellida> Glossiphoniidae> Helobdella.
Aromaticity0.06
Grand average of hydropathy-0.679
Instability index65.69
Isoelectric point7.30
Molecular weight84516.41
Publications
PubMed=23254933

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
transcription regulator complex	GO:0005667	IBA:GO_Central

GO - Biological Function
GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32679
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      90.32|      15|      15|     645|     659|       1
---------------------------------------------------------------------------
  354-  369 (29.34/ 6.57)	QQQMQQQQMQQQqMQQ
  648-  663 (29.79/ 6.79)	QQLQQQQQMQQQhLQQ
  664-  679 (31.20/ 7.49)	QQMQQQQQMQQQrMQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     154.87|      31|      31|     373|     403|       2
---------------------------------------------------------------------------
  305-  336 (39.86/10.91)	PLTFT.....GSPATPTaiALRRAAVNQ...QQQQ...QQ.ATM
  379-  408 (45.61/13.79)	PQNHL.....QQQQSDS..LLQQQQQQQ...QQQQ..qQQTQ..
  409-  444 (36.61/ 9.28)	.SNNLtnvdiNNPGPTL..ALAAQQQQQ...QQQQ..iQQQQRI
  593-  623 (32.79/ 7.37)	PQ.........NPGEMV..GTSAQSINQptlQHQQityQQ..NM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.81|      22|      50|     143|     166|       6
---------------------------------------------------------------------------
  143-  166 (33.49/34.38)	GPYQFPCLGHyKYLNKTTeQLVNL
  192-  213 (40.32/28.70)	GQPDPSCLTK.NYASDST.HLVLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.44|      15|      25|     500|     514|       8
---------------------------------------------------------------------------
  500-  514 (26.99/17.05)	QPLQHLFRS.....SRTVLF
  523-  542 (22.45/13.01)	EAMNSLYRSlsnnfSGCIHF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.72|      18|     429|     277|     301|       9
---------------------------------------------------------------------------
  277-  295 (28.51/24.20)	RPVANLSAVpQQQQQMSVQ
  709-  726 (34.21/11.07)	RPRGPATTL.QQQQQPGVQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32679 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QQLQQQQLQQQQQMQQQHLQQQQMQQQQQMQQQRMQQMPQMHIQSNSQPLRYLLLNQQRPQHHMMNRPRGPATTLQQQQQPGVQTFTTMATDDFPPFDL
2) VPQQQQQMSVQAPNSVAPVHPLTFTGSPATPTAIALRRAAVNQQQQQQQATMQVGGYQASLDPQSQLMQQQQMQQQQMQQQQMQQQQMQQIQQMPQNHLQQQQSDSLLQQQQQQQQQQQQQQTQSNNLTNVDINNPGPTLALAAQQQQ
643
285
741
432










Molecular Recognition Features






MoRF SequenceStartStop




1) LRYLLL
692
697