<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32636
Description |
RNA polymerase II holoenzyme cyclin-like subunit |
Sequence | MAANYWASTQRRHWLFTRERLAEIREAFRERHKLAHSQFPLPDQRLLNIYFSQQLIKLGKRMSTRQQALATAQVYIKRFYTKNEIRHTNPYLVLTTAFYLACKMEECPQHIRFVVGEARSLWPEFITPDVSKLGECEFSLISEMNSQLIVHHPYRTLSGLQSELSLTSDEVALAWSVINDHYLTDLPLLYSPHVIAVMAVMVAVVFKPGPGNFHGSAAPVLAGAMRDGGMNMLAALGDKSGNEPPPKVQKLINWLAESEVDIKAVIECTQELVSLYEVWEQYSEKNCKELLGRMVKTKHLDK |
Length | 302 |
Position | Kinase |
Organism | Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes>
Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus>
Aspergillus subgen. Fumigati.
|
Aromaticity | 0.09 |
Grand average of hydropathy | -0.201 |
Instability index | 46.89 |
Isoelectric point | 8.20 |
Molecular weight | 34532.55 |
Publications | PubMed=18404212
|
Function
Annotated function |
Component of the srb8-11 complex. The srb8-11 complex is a
regulatory module of the Mediator complex which is itself involved in
regulation of basal and activated RNA polymerase II-dependent
transcription. The srb8-11 complex may be involved in the
transcriptional repression of a subset of genes regulated by Mediator.
It may inhibit the association of the Mediator complex with RNA
polymerase II to form the holoenzyme complex. The srb8-11 complex
phosphorylates the C-terminal domain (CTD) of the largest subunit of
RNA polymerase II (By similarity).
ECO:0000250
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | cyclin-dependent protein serine/threonine kinase regulator activity GO:0016538 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP32636
No repeats found
No repeats found
|