<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32632
| Description |
Serine/threonine-protein kinase SSN3 |
| Sequence | MSDQIRASGYFYSQTDDPFAAAFWSQFQDPHVLAARHIPADSSASAAMKAYREYRDRVRKPVLATYTILGFLSSGTYGRVYKARLRTPPQLASSSGTAGIANANAGTGSGTATVGSGASTAKKRGGLLQQHQLLDSPSSSLHATPKSVADGAGVGVNGTPSASPSLSASLGTSTANAPGGSDNTLQLSSNELPDTQIYAIKKFKPDSKETDATIYTGISQSAMREISLNRELSHVNIVTLHQVMLEDKAIYMVFEYAEHDLLQIIHYHSTALRAPIPLAVLKSLLWQLINGVAYLHANWILHRDLKPANILVTSQGVVKIGDLGLARLYSSPLQSLYNGDKVVVTIWYRAPELLLGARHYTTAIDMWSVGCIWGELLALRPMFKGEEAKMDPKTKAAPFQTDQLKRIVEVLGTPNKDRWPAIESMPDYKGWWPHLRLDNYPKTLSRWYATRNKGDDGYELFNSLLQYDPEQRLTANQALEHAWFTAQDPKPTANAFSSLAKPHATYPNRRVIQDDMDPKMKSNYVPPIKSHHMQPWHQVNLNSSQPHRLAQLMYQQEQMRHQQMQTQAPAPAPAQPPAATAVTGRLGHAVGAGSSAVGTAANVGGPAAPPPIAIGSTAGTGGAIGIQSSAASTAPSQHMYNNNPLITIAGTNGGTISNPATVRSSHSIGSTESITPTTSSQPIPAQPSSAPLARTTNLVATATRNQQRKRQRN |
| Length | 713 |
| Position | Kinase |
| Organism | Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus) |
| Kingdom | Fungi |
| Lineage | Eukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina>
Ustilaginomycetes> Ustilaginales> Ustilaginaceae> Ustilago.
|
| Aromaticity | 0.07 |
| Grand average of hydropathy | -0.381 |
| Instability index | 46.16 |
| Isoelectric point | 9.53 |
| Molecular weight | 77022.97 |
| Publications | PubMed=17080091
|
Function
| Annotated function |
Component of the srb8-11 complex. The srb8-11 complex is a
regulatory module of the Mediator complex which is itself dependent
transcription. The srb8-11 complex may be involved in the
transcriptional repression of a subset of genes regulated by Mediator.
It may inhibit the association of the Mediator complex with RNA
polymerase II to form the holoenzyme complex. The srb8-11 complex
phosphorylates the C-terminal domain (CTD) of the largest subunit of
RNA polymerase II (By similarity).
|
| GO - Cellular Component | mediator complex GO:0016592 IBA:GO_Central
nucleus GO:0005634 IBA:GO_Central
|
| GO - Biological Function | ATP binding GO:0005524 IEA:UniProtKB-KW
cyclin-dependent protein serine/threonine kinase activity GO:0004693 IBA:GO_Central
metal ion binding GO:0046872 IEA:UniProtKB-KW
protein serine kinase activity GO:0106310 IEA:RHEA
protein threonine kinase activity GO:0106311 IEA:RHEA
RNA polymerase II CTD heptapeptide repeat kinase activity GO:0008353 IBA:GO_Central
|
| GO - Biological Process | protein phosphorylation GO:0006468 IBA:GO_Central
|
Interaction
Repeat regions
| Repeats |
>MDP32632
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 56.00| 19| 26| 577| 598| 1
---------------------------------------------------------------------------
577- 598 (29.27/22.09) PAA........TAVTgrlGHAVGAGSSAVG
606- 632 (26.72/12.32) PAApppiaigsTAGT...GGAIGIQSSAAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
4| 132.53| 24| 26| 488| 511| 2
---------------------------------------------------------------------------
391- 407 (26.32/11.80) DPKTKAA.......PFQTD..........QLKRI
441- 473 (23.39/ 9.67) .PKTLSRWYATRNKGDDGYelfnsllqydPEQRL
488- 511 (41.80/23.04) DPKPTANAFSSLAKPHATY..........PNRRV
517- 539 (41.02/22.48) DPKMKSNYVPPI.KSHHMQ..........PWHQV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 70.90| 22| 25| 636| 660| 3
---------------------------------------------------------------------------
636- 660 (31.97/25.91) SQHMYNNNPLITiAGTNGGTIsnPA
664- 685 (38.93/20.68) SSHSIGSTESIT.PTTSSQPI..PA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 43.97| 13| 25| 52| 64| 4
---------------------------------------------------------------------------
52- 64 (24.09/16.44) REYRDRVRKPV.LA
79- 92 (19.88/12.24) RVYKARLRTPPqLA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 56.01| 17| 25| 136| 157| 5
---------------------------------------------------------------------------
136- 153 (26.32/20.60) SPSSSlHATPKSVADGAG
163- 179 (29.69/ 9.95) SPSLS.ASLGTSTANAPG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 63.39| 13| 25| 343| 358| 6
---------------------------------------------------------------------------
317- 327 (19.28/ 8.79) VVKI....GDLGL.AR
343- 358 (20.23/18.42) VVTIWyraPELLLGAR
369- 380 (23.88/12.44) VGCIW...GE.LLALR
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|
