<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32570
Description |
Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MQGPEGTQLFSAFPPPPLYYKLFTKENLERVKQRFIRKDGNEAAEGEDGTLEEDKKLAEVFKVPACPTSGTYMMFGDTWRLENVIPSLQDFGITQLYKGLQDEEDKIETVEYDPKSGIVYGYGHAGLHQFDDGTSQFKDVDTSQPNEGENSLEGQEMNEDQGTVIKTADGSEPSAVENKDESITKSIPSARSDGNSIIPRRAYELQLLSTSLMLNFLELLGIMGKAPEQFPQKVENIRVILLNMHHLINEYRPHQARESLLMLLEKQLAHEDSQTRSLKEHNDQIEQALRKLQSLDLDEERKKEFIESVVSSTCHNNHDSTNKDTYGVNTSTEAAEVNTTKNAKIEASLRDLESILES |
Length | 358 |
Position | Middle |
Organism | Schizosaccharomyces cryophilus (strain OY26 / ATCC MYA-4695 / CBS 11777 / NBRC 106824 / NRRL Y48691) (Fission yeast) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Taphrinomycotina>
Schizosaccharomycetes> Schizosaccharomycetales> Schizosaccharomycetaceae>
Schizosaccharomyces.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.740 |
Instability index | 47.17 |
Isoelectric point | 4.75 |
Molecular weight | 40374.40 |
Publications | PubMed=21511999
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 RuleBase:RU364060
|
GO - Cellular Component | euchromatin GO:0000791 IEA:EnsemblFungi
mediator complex GO:0016592 IEA:EnsemblFungi
|
GO - Biological Function | transcription coactivator activity GO:0003713 IEA:EnsemblFungi
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP32570
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 134.92| 41| 46| 67| 111| 1
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67- 111 (67.82/49.71) PTSGTYMMFGDT..WRLENVIPSLQDFGITQLYKGlqdeEDKIETVE
114- 156 (67.10/40.21) PKSGIVYGYGHAglHQFDDGTSQFKDVDTSQPNEG....ENSLEGQE
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 139.95| 43| 53| 170| 212| 2
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170- 212 (70.20/49.76) GSEPSAVENKDESITKSIPSARSDGNSIIPRRAYE..LQLLSTSL
224- 268 (69.74/49.39) GKAPEQFPQKVENIRVILLNMHHLINEYRPHQAREslLMLLEKQL
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 46.78| 14| 59| 282| 295| 3
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282- 295 (23.84/15.86) NDQIEQALRKLQSL
342- 355 (22.94/15.02) NAKIEASLRDLESI
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