<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32533

Description Uncharacterized protein
SequenceMNPAGQMPPGMMAGMGMAGGPAAQGGGQAAMAAVMAKLKSQPPPTVGWQAEIPTADRWKIINQIASSLRLVQSELDGPRAVKMAEAFEEHTFRTASSKDEYIGACRGKMQQIQETRMRKQADTDQLMRDQQFLNRNPQLAQQQQQQLLLARMQAGQMGGPQNPQQSGMGPGMMPPNINIAAAMANNPALQAQMAMAAQAQPGLLQQQQQQQQQQQQQQQQQQQQQQAAAAAAQQQAQQNQLSQLPPNHPLNQYRNMPKEQAIEHLAKTMMQQAQPQHIQHIMSQLGVLSEEQKAQCERLKITPVEMFFRNAAAKKLLQSHVITAGGMQGMPGAGGVPGGMSTGPGGTPQLNAQQIANQQIHSRQAQLAAAQAQQARILQAQAGLGRGQNIGQPPPFDNNLFMNDIQSYLKQQQQQQQQQSGNAQVDAMAAAKKAAAAVAAQQGRGMSNAAGMPTSMAPQGTPQLSAAAAQQQQQQQQQQQHQQLLLLRQQAAAAQQRLNQQQSPPQPPNQPSLVGQHPSPTMNLLNQSHRPASATGSQAAQAAQAQQQLQQARLAELQARNQLQQQQQAQHQQQQAGMAQRPPGNFTIPPGFPIHKFQNMPPEQLQQAIHNFNKQAQVQQALAQQQQQQGQNPAVLLQQQQAALNAQNAMRNGMAGNQASQIQAAQNALLQQQLNNPGMTAELAQKIQQQKMMNLHMQQGALAQKLAAQSVKPQQPGQQAQNAAQQPQQQQQQQQAQTVQPPQPGRPQLPFIPDIPFPPAFDGMKYPPNAVAFLKKHFPQLEIPVNNLPNWGTFKDWAKQVSVDVAMRVRQLHFLHIQEMAKKNAFVGAMQIQYQEFVTRLGNSRSAHLQQAQMQAAHAQAQAREAQQAAAPHMSPPKPAVKQPTPSQTQAPTPKMAQQSVTPNQQQQQQQQQQQQQQQQRSLKRPAEESASSQVTQSQAQAQAQAQAQQQAQQQAQQQAQQQAQQQAQQQQQQQQGQKAGDWQSFLQKLLVMPPEMQQQLLNQPRMAQLPPERKAEITRVIQLSRTKLQNAQNQQRSAAMQAQLAAQNQNQAQNQNQTQVKQEPQQPARPPTAQQPPQQKPQAAAPAAPGPQAAAPTAPIDPAKHLLKNKEQVQLIRQEETQRALARPIIPMSNEVKAVMKQALKESSQALLRMEQWMPMFLMLLPAERIVRELFQTRATVATQYEDPQFQNTKDNFTITPEDLEAAKSQINRYFNYVKAQVPKLNEQRIKQGQPPIPMSATMPSNLQQQQQHQLLQQRQALQQQQAQQQHQQNLNQQAAAKAPVPNLGQVEFQKQQQQQQQDLKHPAAALQQPAQQVGKSGAPAAPTPPIPTAASFPLHIPPRKKPKSGPESPNISKAPKPDLKLTPTQLQAQAAAAAAAQAPAMPAPPVANQAAPKGNLPLEYTHLCIVKTCEYNTRGFANQAELLRHLKEDHKDDINRGSKQPPPDPRAQREKEARMIEERNKMITNPLEYTLGSVAEALNLNRDGTRKIKEEKPDDKEATASVKAPTPKTTGSTPLAKTPSKAAPPTPKLDTKEAAEKSAAGLPTPPSLGWDDTMISPTVIHQAFEGLEEITDLVIDSIDISMILTPDDSDDLFSDDLKIPGISPPLPSNALPEARNGGDAMDMNEDEMKDFEGWNPFGIRNCGPIGLVEDIDWELVDLPGTGPNSGNSSTLSGWDNSFFELRA
Length1689
PositionTail
OrganismDactylellina haptotyla (strain CBS 200.50) (Nematode-trapping fungus) (Monacrosporium haptotylum)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Orbiliomycetes> Orbiliales> Orbiliaceae> Dactylellina.
Aromaticity0.03
Grand average of hydropathy-0.841
Instability index65.54
Isoelectric point9.55
Molecular weight185372.84
Publications
PubMed=24244185

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32533
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|    1662.53|     260|     260|     130|     389|       1
---------------------------------------------------------------------------
  130-  389 (465.17/75.57)	QQFLNR.NPQLAQQ.....QQQQ......L........LLARMQ.AGQMGGPQ....................................NP..QQSGMGPGM...MPPNINIAAAMANNPALQAQM..A..MAAQA.QPGLLQQQQQQQQQQQQQQQQQQ...QQQQAAAAAA.........QQQAQQNQLSQLP..PNHP...LNQYR..NM..PK....EQAIE.....HLAKTMMQQAQPQHIQHIM.S.QLGVLSEEQ...........KAQCE...RLKITPVEMFFRNAAAKKLLQSHVITAGGMQGMPGAGGVPGGMSTGP.GGTP.....QL..NAQQIANQQIH..SRQAQLAAAQ.....AQQARILQA..QAGLGRGQN
  399-  634 (299.33/44.80)	NLFMNDiQSYLKQQ.....QQQQqqqsgnA........QVDAMA.AAKKAAAA....................................VA..AQQGRG................MSN..A..AGMptS..MAPQG.TPQLSAAAAQQQQQQQQQQQHQQlllLRQQAAAAQ..........QRLNQQQSPPQ.P..PNQP..sLVGQH..PS..PTmnllNQSHR.....PASATGSQAAQAAQAQ.............QQ...........LQQA....RL..A..ELQARNQLQQQQQAQHQQQQAGMAQRP.....PGNF.TIP.PGFPihkfqNM..PPEQL.QQAIHnfNKQAQVQQAL.....AQQ....QQ..QQ..GQNPA
  635-  868 (297.06/44.38)	V.........LLQQ.....QQAA......LnaqnamrnGMAGNQ.ASQIQAAQ....................................NAllQQQLNNPGMtaeLAQKIQ.QQKMMNLHMQQGAL..AqkLAAQSvKP...QQPGQQAQNAAQQPQQQQ...QQQQAQTVQP.........PQPG.RPQLPFIPdiPFPP.....AFD..GMkyP.....PNAVA.....FLKKHFPQLEIP..VNN.L.P.NWGTFKDWA...........K.........QVS.VDVAMR...VRQLHFLHI......QEMAKKNAFVGAM..............QI..QYQEFVTRLGN..SRSAHLQQAQ.....MQAAHA.QA..QA..REAQQ
  887- 1151 (318.33/48.33)	SQTQAP.TPKMAQQsvtpnQQQQ....................Q.QQQQQQQQ....................................QQ..QRS.....L...KRPAEESASSQVTQS..QAQA..Q..AQAQA.QQQAQQQAQQQAQQQAQQQAQQQ...QQQQQGQKAG.........DWQSFLQKLLVMP..PEMQqqlLNQPRmaQL..PP....ERKAEitrviQLSRTKLQNAQNQQRSAAMqA.QLAAQNQNQ............AQNQnqtQVKQEP.QQPARPPTAQQPPQQKPQAA..A...PAAPGPQAAAPTAPiDPAK.....HLlkNKEQV..QLIR..QEETQRALARpiipmSNEVKAVMK..QALKESSQA
 1160- 1443 (282.64/41.70)	PMFLML.LP..AER.....IVRE......L........FQTRATvATQYEDPQfqntkdnftitpedleaaksqinryfnyvkaqvpklNE..QRIKQG......QPP.IPMSATMPSN..LQQQ..........Q.QHQLLQQRQALQQQQAQQQHQQN...LNQQAAAKAPvpnlgqvefQKQQQQQQ.QDL....KHPaaaLQQ........PA....QQ.........VGKSGAPAAPTPPIPTAA.SfPLHIPPRKKpksgpespnisKAPKP...DLKLTP..........TQ.LQAQAAAAAAAQA.PAMPAPPVANQAAP.KGNL.....PL..EYTHLCIVKTC..EYNTRGFANQ.....AELLRHLKEdhKDDINRG..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.84|      15|      16|    1578|    1592|       3
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 1578- 1592 (25.80/16.38)	DLVIDSIDISMILTP
 1597- 1611 (28.04/18.44)	DLFSDDLKIPGISPP
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.50|      11|      16|    1640|    1650|       7
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 1640- 1650 (24.68/14.61)	WNPFGIRNCGP
 1659- 1669 (21.82/12.06)	WELVDLPGTGP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32533 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AQAGLGRGQNIGQPPPFDNNLFMNDIQSYLKQQQQQQQQQSGNAQVDAMAAAKKAAAAVAAQQGRGMSNAAGMPTSMAPQGTPQLSAAAAQQQQQQQQQQQHQQLLLLRQQAAAAQQRLNQQQSPPQPPNQPSLVGQHPSPTMNLLNQSHRPASATGSQAAQAAQAQQQLQQARLAELQARNQLQQQQQAQHQQQQAGMAQRPPGNFTIPPGFPIHKFQNMPPEQLQQAIHNFNKQAQVQQALAQQQQQQGQNPAVLLQQQQAALNAQNAMRNGMAGNQASQIQAAQNALLQQQLNNPGMTAELAQKIQQQKMMNLH
2) FANQAELLRHLKEDHKDDINRGSKQPPPDPRAQREKEARMIEERNKMITNPLE
3) FSDDLKIPGISPPLPSNALPEARNGGDAMDMNEDEMKD
4) GACRGKMQQIQETRMRKQADTDQLMRDQQFLNRNPQLA
5) LNEQRIKQGQPPIPMSATMPSNLQQQQQHQLLQQRQALQQQQAQQQHQQNLNQQAAAKAPVPNLGQVEFQKQQQQQQQDLKHPAAALQQPAQQVGKSGAPAAPTPPIPTAASFPLHIPPRKKPKSGPESPNISKAPKPDLKLTPTQLQAQAAAAAAAQAPAMPAPPVANQAAPKG
6) LNLNRDGTRKIKEEKPDDKEATASVKAPTPKTTGSTPLAKTPSKAAPPTPKLDTKEAAEKSAAGLPTPPSLGWDDTMI
7) NSRSAHLQQAQMQAAHAQAQAREAQQAAAPHMSPPKPAVKQPTPSQTQAPTPKMAQQSVTPNQQQQQQQQQQQQQQQQRSLKRPAEESASSQVTQSQAQAQAQAQAQQQAQQQAQQQAQQQAQQQAQQQQQQQQGQKAGDWQSFLQKLLVMPPEMQQQLLNQPRMAQLPPERKAEITRVIQLSRTKLQNAQNQQRSAAMQAQLAAQNQNQAQNQNQTQVKQEPQQPARPPTAQQPPQQKPQAAAPAAPGPQAAAPTAPIDPAKHLLKNKEQVQLIRQEETQRALARPIIPM
8) QQGALAQKLAAQSVKPQQPGQQAQNAAQQPQQQQQQQQAQTVQPPQPGRPQLPFIPD
9) QQQQLLLARMQAGQMGGPQNPQQSGMGPGMMPPNINIAAAMANNPALQAQMAMAAQAQPGLLQQQQQQQQQQQQQQQQQQQQQQAAAAAAQQQAQQNQLSQLPPNHPLNQYRNMPKEQAIEHLAKTMMQQAQPQHIQHIMSQL
10) SHVITAGGMQGMPGAGGVPGGMSTGPGGTPQLNAQQIANQQIHSRQAQLA
380
1422
1599
103
1226
1484
843
698
143
319
696
1474
1636
140
1400
1561
1133
754
285
368










Molecular Recognition Features






MoRF SequenceStartStop




1) QLQAQAAA
1371
1378