<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32502

Description Uncharacterized protein
SequenceMRESRPDKVDPPIYELRPPEWLPKVSTSADLGYIGFHPPHPGQPEDVLSQSNIQNGFSVGHTVSAETFTSVEAVNQHLKGEVLTELDDFMNQVFARRAESVPAIPPSSFRLPSRVTLNDAKRHAWFEDLANPDVPLQKLGKSVPHGAKGGDLLDLLQAKNVAIPRAVWFLRVFGANETAGLRNKPSYNPTQYSVEWANVVTAHLKKQLSEIALPVAVRAGMNVKQTFKGVLSDPASRERWMSRFSYCLDLLRTFYAEGLVDNRTFLSWLVQQMASCNLAQAGFVARLADEYLDGMLVSRALTRPFVDACLNKLAEIKNTAVQDALPNLESSLTSILQRVCLGLPDAFVSPRTWATHADLISAVLRHKIGSLTSQAVQQDLEDNITDITRRNEALLLRSLPPRALADLSSAVRDVQLLNSLSTIDALDRAPFFDAHSEDVAFFSRKLDLLLSWCVTPLQYGDHRTYAAMSLLSHWRNQAQECAWRRNVPPNAGPAQVLQDLLFDWLDDSEVAGDPENLRAIAWLYGGLAKHDLFSYAEYLQRLVSRGEQGLSDPEKPSRHRRFLRWIPLQKSTPALVNQRKVILYGVRARETPEDAVEKQLRKEVRALLPELFDGMIQSNPVSLSSIAAICPLLINACRFEQIRTVGQWFLPVLRKYIMRHSGDQTDSFAIASVYCTTITLLELVKCYESILEMSLLALQHVTTSEMLTAVLETLRRHLKVWICMDATGSITSALYEAHQYWRHQGIQTRALLDLLTEMDAGRHLDQASRDQLEADVASLATALCPHSDHRDSVPAVLPEILLLAQDLTQDAPSRLANSLWYKYRTAPDWAWKVWDNTVASLRQIPMMSSDPSSRHICALRYGSFLLHVDQHLPRGFDEQVLEWCLGSGKNEVAALTSDSWPIVTIVLLFLAVQGALTITTILQGFVYPAWQSGANCGSPEQGVAVQVFLCAANDLFERLLLASDCNLDDFPPSDLLQLQRLFTRRLDVYGEKHFPPLVAMIPNLVFIEESEFHHDDIRSASRMIREKLCRRSDFRQGAYRNLDTVRVAIERTLESETISPRLHKPLVNALRLILSDSGSDELGLHQWQAVSSLFSPWKLAATAIEMKFVLRGIAEGMSKDETRREASANLDKLTAQLLHHSMTSEQVDFVADMARGVGHAVAGKFVNNGLKCIAELIGGVPQDMESQKLRDFKTRTGELLRLLVQVLDRCSEERHAAPQLDALIQEQLFNGICVKLEAAEVALKSSTFEESSDIPGFIIELARLLQFDMRCENIWTPPTKELLPRMTEVVFRLALLHSSGNHFNVVSYSLLLDTLCYLLDAYPVDLRSQTVDLFRLYPQISLSDLPPDMPPPFRVRVRSLLPYVNLAGPVENLAYASAEPSGSGDVPESQLVPVQNRPWEWVEYLGDPITLDPKEEEKEKQERERLRARQLVKNTTSLSLELFGTQVTSDRAVHVNDADSRLEGDLRSFQDGLWGESIFKRDWRESRVQLVGSGAGRSKSEEDEDGTAAAGMTSSLHVSEKRKQGSRKPSPASSVVSRSSAHPSHHSGSRSTTPTRRSVVGSSMSEPIDVDSVAVSVGASKRARDQDGDDEVEILDTVPSGSKAKKARKTTGRKSGKKKS
Length1620
PositionKinase
OrganismGloeophyllum trabeum (strain ATCC 11539 / FP-39264 / Madison 617) (Brown rot fungus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Gloeophyllales> Gloeophyllaceae> Gloeophyllum.
Aromaticity0.07
Grand average of hydropathy-0.242
Instability index49.83
Isoelectric point6.05
Molecular weight180950.89
Publications
PubMed=22745431

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP32502
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.97|      21|      21|    1523|    1543|       1
---------------------------------------------------------------------------
 1523- 1543 (37.94/22.94)	KQGSRKPSPA.SSVVSRSSAHP
 1546- 1567 (34.03/19.74)	HSGSRSTTPTrRSVVGSSMSEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.55|      12|      17|     902|     913|       2
---------------------------------------------------------------------------
  902-  913 (19.49/11.20)	IVTIVLLFL..AVQ
  918-  931 (18.05/ 9.85)	ITTILQGFVypAWQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.64|      44|      78|     324|     376|       3
---------------------------------------------------------------------------
  300-  353 (59.78/57.56)	ALTRPFVDACL.NKLAEIKNTAVqdAlpnLESSLTSILQR...VCL.GLPdafvsPRTW
  354-  404 (55.86/39.28)	ATHADLISAVLrHKIGSLTSQAVqqD...LEDNITDITRRneaLLLrSLP.....PRAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.59|      17|      22|    1571|    1588|       6
---------------------------------------------------------------------------
 1571- 1588 (24.41/18.37)	DSVAvSVGASKRARDQDG
 1596- 1612 (29.18/17.41)	DTVP.SGSKAKKARKTTG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      18.88|       4|      78|     471|     498|       7
---------------------------------------------------------------------------
  471-  474 ( 9.44/13.97)	LSHW
  501-  504 ( 9.44/ 6.30)	LFDW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     239.22|      73|      82|    1175|    1255|      11
---------------------------------------------------------------------------
 1175- 1249 (114.07/86.02)	ELIGGVPQDMESQKLrdFKTRTGELLRLLVQVLDRCSEERHAAPQLDALIQEQLFNGICVKLEAAEVALKSSTFE
 1260- 1332 (125.15/75.38)	ELARLLQFDMRCENI..WTPPTKELLPRMTEVVFRLALLHSSGNHFNVVSYSLLLDTLCYLLDAYPVDLRSQTVD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.97|      18|      19|     777|     794|      12
---------------------------------------------------------------------------
  777-  794 (32.10/19.19)	ASLATALCPHSDHRDSVP
  795-  812 (28.88/16.45)	AVLPEILLLAQDLTQDAP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.20|      21|      91|    1022|    1043|      16
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 1000- 1021 (32.22/18.89)	MIPNlVFIEESEFHHDDIRSAS
 1023- 1043 (36.98/17.75)	MIRE.KLCRRSDFRQGAYRNLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.80|      17|      19|    1459|    1475|      20
---------------------------------------------------------------------------
 1459- 1475 (30.91/19.62)	DSRLEGDLRSFQDGLWG
 1476- 1492 (29.89/18.69)	ESIFKRDWRESRVQLVG
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Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP32502 with Med12 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) QLVGSGAGRSKSEEDEDGTAAAGMTSSLHVSEKRKQGSRKPSPASSVVSRSSAHPSHHSGSRSTTPTRRSVVGSSMSEPIDVDSVAVSVGASKRARDQDGDDEVEILDTVPSGSKAKKARKTTGRKSGKKKS
1489
1620

Molecular Recognition Features

MoRF SequenceStartStop
1) DPPIYELRPPEWL
2) KRARDQDGDDEVEILDTVPSGSKAKKARKTTGRKSGKKKS
10
1581
22
1620