<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32482

Description Mediator of RNA polymerase II transcription subunit 17
SequenceMSGDQDDVADTVEKGIQLALDPNLITLPLHSTSASPLTNTSNGDSQAPDNPKKDQMDIDSDPPNVKTTGGQSLVNNPYGLFGQMPLEQLIPMVLRQKGPGFKFADLSEEAIEEEIEKEKAGKLDSPISASMNSPQTKPEDVSPANLLSKDEDEIGESNTEQKDEGITQEQFVKLRREMLEHINIAMNESSLALEFLSLLLSSVRESVALSSMSPFLKKTAPVGSLNSDKLPLEPKTVPEKLTMEIIDRGWKLRCLNESRSVLKENHTMLEEKLRKEHEYWKKIAQYISNKDVIFKLRDKSTGLKSLGVKYGYEDSGSTYKHDRGVAVLRTNPESNTLELVPIVGENSRLQHNEKFVRIRIYTKIEFEDDYILTGESSLDRVFSSGGSLGRTDHEDIRVQIEKLKTLIFEQEMMYQLKKECSRLISYGVTIENENKVVMELPKEKFEIELVSLDDVSVVNHEQDAPKTNDKRATLMLITLRMLLVVMFKKNLIQRLTSSIRITSLNVEKDILLIRPLLGRMRHQNYKLLLRKILKTYVLDIVEGSRLSEVPVNTSRQQVIQEANLDVHVSKLKKEIKAFDRLLNICKTKFEIALPGSDKLSLTLENPKYCNLAVRVQYHNDQENVSFDTEFSEFKEVEEILHFIVNEYIQGKG
Length652
PositionHead
OrganismZygosaccharomyces bailii (strain CLIB 213 / ATCC 58445 / CBS 680 / CCRC 21525 / NBRC 1098 / NCYC 1416 / NRRL Y-2227)
KingdomFungi
Lineage
Aromaticity0.06
Grand average of hydropathy-0.479
Instability index44.08
Isoelectric point5.48
Molecular weight74081.82
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32482
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.83|      11|      24|     409|     419|       1
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  409-  419 (19.46/12.94)	EQEMMYQLKKE
  433-  443 (18.38/11.82)	ENKVVMELPKE
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     255.19|      87|      93|      44|     135|       2
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   44-  135 (132.42/92.93)	DSQAPDN.PKKDQMDIDSDPPNVKTTGgqsLVNNPYGLFGQMPLEQlIPMVLRQKGPGFKFADLSEEAIEEEIEKEKAG...KLDSPIsASMNSPQ
  139-  229 (122.77/72.21)	EDVSPANlLSKDEDEIGESNTEQKDEG...ITQEQFVKLRREMLEH.INIAMNESSLALEFLSLLLSSVRESVALSSMSpflKKTAPV.GSLNSDK
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     233.11|      79|     296|     243|     322|       3
---------------------------------------------------------------------------
  243-  322 (132.61/96.01)	MEIIDrGWKLRC..LNESR.SVLKE.NHTMLEEKLRKEHEYWKKIAQYISNK.DVIFKLRDK.STGLK.....SLGVKYGYEDSGSTYKHD
  538-  627 (100.51/67.46)	LDIVE.GSRLSEvpVNTSRqQVIQEaNLDVHVSKLKKEIKAFDRLLNICKTKfEIALPGSDKlSLTLEnpkycNLAVRVQYHNDQENVSFD
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32482 with Med17 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DLSEEAIEEEIEKEKAGKLDSPISASMNSPQTKPEDVSPANLLSKDEDEIGESNTEQKDEGITQEQ
2) LPLHSTSASPLTNTSNGDSQAPDNPKKDQMDIDSDPPNVKTTGGQSLVNNPYGLF
105
27
170
81










Molecular Recognition Features






MoRF SequenceStartStop




NANANA