<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32464

Description ER luminal-binding protein
SequenceMAAAWKTRASLTVFAIVLFGSLFAFSIAKEEATKLGTVIGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWVAFTDGERLIGEAAKNQAAVNPERTIFDVKRLIGRKFDDKEVQRDMKLVPYKIVNKDGKPYIQVKVKDGETKVFSPEEISAMILTKMKETAEAYLGKTIKDAVVTVPAYFNDAQRQATKDAGVIAGLNVARIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSILTIDNGVFEVLATNGDTHLGGEDFDQRVMEYFIKLIKKKHGKDISKDNKALGKLRREAERAKRALSSQHQVRVEIESLFDGVDFSEPLTRARFEELNNDLFRKTMTPVKKAMDDAGVSKNQIDEIVLVGGSTRIPKVQQLLKDYFDGKEPSKGVNPDEAVAYGAAVQGGILSGEGGDETKDILLLDVAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQTTVTISVFEGERSMVKDCRLLGKFDLTGIPPAPRGTPQIEVTFEVDANGILNVKAEDKASGKSEKITITNDKGRLSQEEIERMVKEAEEFAEEDKKVKERVDARNSLETYVYNMRNQINDKDKLADKLESDEKEKIETATKEALDWLDDNQSAEKEDYDEKLKEVEAVCNPIITAVYQRSGGAPGGASEDSNDDDDSHDEL
Length668
PositionUnknown
OrganismCapsicum annuum (Capsicum pepper)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Solanoideae> Capsiceae> Capsicum.
Aromaticity0.06
Grand average of hydropathy-0.446
Instability index27.87
Isoelectric point5.06
Molecular weight73542.29
Publications
PubMed=24441736
PubMed=29089032

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central
endoplasmic reticulum chaperone complex	GO:0034663	IBA:GO_Central
endoplasmic reticulum lumen	GO:0005788	IBA:GO_Central
membrane	GO:0016020	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
endoplasmic reticulum unfolded protein response	GO:0030968	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central
ubiquitin-dependent ERAD pathway	GO:0030433	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32464
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.01|      24|      27|     539|     565|       1
---------------------------------------------------------------------------
  539-  562 (39.07/26.22)	KGRLS.......QEEIERMVKEAEEFAEEDK
  588-  618 (32.94/14.18)	KDKLAdklesdeKEKIETATKEALDWLDDNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     136.11|      38|     244|     383|     424|       2
---------------------------------------------------------------------------
  110-  145 (38.67/13.00)	FDDKEvqrdmklvPYKIVNKDGKPYIQVKVKDG...........ETK..
  213-  239 (26.95/ 6.14)	......................AIAYGLDKKGGeknILVFDLGGGTFDV
  386-  423 (70.49/39.38)	FDGKE........PSKGVNPDEAVAYGAAVQGG...ILSGEGGDETKDI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.18|      19|      22|      64|      84|       3
---------------------------------------------------------------------------
   64-   84 (27.58/25.89)	DQGNrITPSWVAFtDGERLIG
   89-  107 (33.60/20.73)	NQAA.VNPERTIF.DVKRLIG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32464 with Med37 domain of Kingdom Viridiplantae
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