<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32437

Description Rna polymerase ii holoenzyme cyclin-like subunit
SequenceMAASYWDSTQRRYWEFTKEQLADLRQRKQDEERSLVQVYPLPEWRHLFIFFNTHLTRLAKRMQVRQQALATAQVYLKRFYCKVEIRRTNPYLTMTTALYLACKTEECPQHIRQVVQEAKMLWPDTHCLDIPRLGECEFYMISELSSQLIVHAPYRTLNTLQLELSLTAEEFIQAWTVTGGAPGIGGTQSSLPPPPSLHMSLSSLSGQGSNNTPGGSGTPGGAGGPGTPGIGGAAGTPTTAGSAGYPGMSAGAGGSAMAMVQANARAVVSAAIQNQGTPTGSQGSAGGSNALNSGAGGGNTAGTPTEEAPPADGGRGATLQWLFRWLTDSGLDLEATIDCTQEMISFYMAGEEYSEKQTREQVNRFIKARGLDR
Length373
PositionKinase
OrganismOphiostoma piceae (strain UAMH 11346) (Sap stain fungus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Sordariomycetidae> Ophiostomatales> Ophiostomataceae> Ophiostoma.
Aromaticity0.08
Grand average of hydropathy-0.382
Instability index52.48
Isoelectric point6.33
Molecular weight40219.76
Publications
PubMed=23725015

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32437
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     121.53|      27|      28|     204|     230|       1
---------------------------------------------------------------------------
  204-  230 (54.16/19.42)	LSGQGSNNTPGGS.GTPG.......GAGGPGTPGI
  231-  260 (41.23/13.35)	GGAAGTPTTAGSA.GYPG....msaGAGGSAMAMV
  272-  302 (26.13/ 6.26)	IQNQG...TPTGSqGSAGgsnalnsGAGGGNTAG.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.68|      29|      33|      11|      39|       2
---------------------------------------------------------------------------
   11-   39 (50.90/35.38)	RRYWEFTKEQLADLRQRKQDEERSL..VQVY
   45-   75 (45.77/31.19)	RHLFIFFNTHLTRLAKRMQVRQQALatAQVY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.94|      26|     200|     122|     147|       4
---------------------------------------------------------------------------
  122-  147 (51.62/32.41)	WPDTHCLDIPRLGEC.....EFYMISELSSQ
  325-  355 (42.32/25.48)	WLTDSGLDLEATIDCtqemiSFYMAGEEYSE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32437 with CycC domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PGIGGTQSSLPPPPSLHMSLSSLSGQGSNNTPGGSGTPGGAGGPGTPGIGGAAGTPTTAGSAGYPGM
2) VVSAAIQNQGTPTGSQGSAGGSNALNSGAGGGNTAGTPTEEAPPADGGRGATL
182
267
248
319










Molecular Recognition Features






MoRF SequenceStartStop




NANANA