<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32419
Description |
Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MDEQQSTRSAWPDPPNYYKRYTSDNLQLLKQSKRSGIFPEQPINKPPVPEFQLEALEPPLPPTDDYTVFDQKWQINDRLPTLQELGVKQIYPEDSIGKQTQAMDVCQQFDRTTIDRVQELKKLNRSLIVQYLDLLDVLEKNPSEYGKHIENISTILLNMHHILNAYRPHQARETLRLLMEHQLAKKRQQTAELKA |
Length | 195 |
Position | Middle |
Organism | Mucor circinelloides f. circinelloides (strain 1006PhL) (Mucormycosis agent) (Calyptromyces circinelloides) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Fungi incertae sedis> Mucoromycota> Mucoromycotina>
Mucoromycetes> Mucorales> Mucorineae> Mucoraceae> Mucor.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.844 |
Instability index | 68.04 |
Isoelectric point | 6.22 |
Molecular weight | 22904.78 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 RuleBase:RU364060
|
GO - Cellular Component | core mediator complex GO:0070847 IEA:EnsemblFungi
mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | negative regulation of transcription by RNA polymerase II GO:0000122 IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II GO:0045944 IEA:EnsemblFungi
|
Interaction
Repeat regions
Repeats |
>MDP32419
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 47.78| 16| 17| 154| 169| 1
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145- 165 (23.57/15.58) YGKHienisTILLNMHHILNA
166- 185 (24.20/16.16) YRPH.qareTLRLLMEHQLAK
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 55.67| 16| 16| 83| 98| 2
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83- 98 (27.02/16.31) QELGVKQIYPEDSIGK
101- 116 (28.65/17.64) QAMDVCQQFDRTTIDR
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