<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32413

Description Uncharacterized protein
SequenceMAGRHQGGGNNSNNNNLNIPFPPSQNNNAQYNHQQQQQQHQQQQHQQQQQQHQQAYGNASPYSTNSTSSPGYHSPNVHPRNNQNTPLKKYTLQPSPRLLPLSKSMPSLGFPGMFPQRPGQDEDILTESNVRHGFVDRPVVSNEHTCAHDIVYGKLQDDQRLLNELGSFMVDVLQRQSRAGCITGPSSFRPPIRTTLIDSKREQWMQELAAGIVPLKKLARNVPHGFKGDKLLETLAAKQVPFLRATWYIKIVGLSEMSQRSASNAATSVGPQPIQWTGTVTSHLKKQLSELIPLSNNPTNAVSPHPTAGTPGRGYKGYNASNHHDNAPKPWASPENRARFEHRWSYSVKLARWQYFEGLLDQRTFLKWTLDTLAGSGSFEIMWLVLTGIIQDYIDEYKRNRTLTKLLIETLIKSYSALTQFIRQSQSDTATLSVHYGLQNDIEHLLQSLFLSTPDMFVVPKLYHQYRYLFNSILGDESRQKPSKSLPDVCRVMKEYWTMIKARNEVFCGTLEENEMKGDHHPADMDNKAQTSDSIPPDAVASSSTPSSASSNISEAVYEERVVHVLDSIGRHVDSITGLLLDNDTWVDIKGHTAKSASKSIFGTTRLQPQALIKLINIMCRWATSESRYGDWKAYLVASILLSWREQDKSNDNKVLLQDALIRFLDDEACPKANEATAIDSQTIDAIEQDHTEKTNTPVIYLFDVLIRLQLFSYQKYLLRLIARGDLEPKRRHVKQIQQCLHHLASFPLLSPAPPYLINQRRVALYGTRSDCDSKEEVESLERLKHLARMAVTGFDHHDTDCLFGAEAKEMTQPVPTDSMQSYELSLTEEIKSEFISAMDTTSRYSLLNFTNWLLNEVKRFVVKSIQIGEDNWRVMTLPGSCLLNTRQFVTIIRIMECAKDYLTITEVTLWVLEKSNDPVLYPYIIDSLRKYANYWKLTNSSTRVANAVWAKHLSLSNRGNRERCIMMYMVQLVQEGYQMDDLVREQLKQDLQVKSKLRGRYSSSVSVKDELTQLAKEPVTSSLQLVSESLSVPSQNATGWIGAILESAGEVLRMVAKEKHITEQAKSHQQPFSSALYDFHRIVRAFANVLKDVANHTTLTGQADQVVIHWLCNNEIVLQDMNQECSWVPFFVAILVAYNVINLSNVVKEFALPWFEQVNRDCQQHYGAEESKLAVFCQNLIALIRLLIIQTSNQPKSEEETNTVHWQLRVEDFYRLEVQRQSQLASSLDRIEPMFGLMERLVMIATSLPLSSNLLQDLVMLRADLLQITWFRQACLRDLNGVYQRFAAREAEAAMEKRMKKKMLDIVDELIGGNSLVGERQGAIVQDTTPDFVDKLHRVFLNVSQWNEAQCRVQVNLLLDNISLSDGHSQNPNNPHILGDDISMDMTPTESVSSSNKDLQSFVYFFYDVVLADGKEESDPVKAQRRFQFFKNLIHELREPVLLELLHHGARLLEGDPSQSFPENVLLMQATDPGQHFDSAKYAYRSQAFLNITQHMLAENVWSNEKKIELVKTVFGQITRFKNSLSIYRVMQGANVCYADATNALQLVKNNVDMAIALLVTEGPAENTGEETEKDLKLSIQDIRNSLLVRLRLMVPFASLIWEHPKPNECDILEWIKVLVSLLGNPIVHGNGSQERFFEFVLDFVSLLIDAEVPKELKKKSLNLLGSMHNELTSVPAMFHSRVKRIMPFLTHNLYLANTKLASSMLGLPPTNDPQQQQQHLESCLEQSKPWEWLEDYVSEPPHDNDAPISLSLFNAKKSKRVDNTYVRWFKFGFDEGSSSSRRRRMNQDTTHISGIEVDKHKDEMMDENGFIFIVDDDEEMDTTTPNNAKKRKVEMEEGELP
Length1843
PositionKinase
OrganismMucor circinelloides f. circinelloides (strain 1006PhL) (Mucormycosis agent) (Calyptromyces circinelloides)
KingdomFungi
LineageEukaryota> Fungi> Fungi incertae sedis> Mucoromycota> Mucoromycotina> Mucoromycetes> Mucorales> Mucorineae> Mucoraceae> Mucor.
Aromaticity0.08
Grand average of hydropathy-0.433
Instability index45.96
Isoelectric point6.19
Molecular weight210011.95
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32413
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     124.36|      35|     247|      60|      97|       1
---------------------------------------------------------------------------
   60-   97 (55.09/35.42)	SPYSTNSTSSPGYHSPNVhPRNNQNTPlKKYTlQPSPR
  303-  337 (69.26/32.85)	SPHPTAGTPGRGYKGYNA.SNHHDNAP.KPWA.SPENR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.20|      25|     247|    1354|    1379|       2
---------------------------------------------------------------------------
 1354- 1379 (39.93/31.17)	VQVNLLLDNISLSDGHSqNPNNPHIL
 1590- 1614 (47.27/32.14)	VRLRLMVPFASLIWEHP.KPNECDIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.46|      35|     166|     748|     787|       4
---------------------------------------------------------------------------
  748-  787 (51.16/38.34)	PLLSpapPYLINQ.RRVALYgtRSDCDSKEEVESLERLKHL
  919-  954 (60.29/31.14)	PVLY...PYIIDSlRKYANY..WKLTNSSTRVANAVWAKHL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.99|      25|     213|     813|     838|      11
---------------------------------------------------------------------------
  813-  838 (38.51/29.85)	QPVpTDSMQ..SYELSLTEEIKSEFISA
 1018- 1044 (39.48/24.79)	EPV.TSSLQlvSESLSVPSQNATGWIGA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32413 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DENGFIFIVDDDEEMDTTTPNNAKKRKVEMEEGELP
2) LEENEMKGDHHPADMDNKAQTSDSIPPDAVASSSTP
3) MAGRHQGGGNNSNNNNLNIPFPPSQNNNAQYNHQQQQQQHQQQQHQQQQQQHQQAYGNASPYSTNSTSSPGYHSPNVHPRNNQNTPLKKYTLQPSPRLLPLSKSMPSLGFPGMFPQRPGQDEDILTESNVRHGFVDRP
4) SNNPTNAVSPHPTAGTPGRGYKGYNASNHHDNAPKPWASP
1808
511
1
295
1843
546
138
334










Molecular Recognition Features






MoRF SequenceStartStop




1) KRKVEMEEGEL
2) TYVRWFKFGF
1832
1766
1842
1775