<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32389

Description Mediator of RNA polymerase II transcription subunit 16
SequenceMPLILDNPMPVELNDVDDLFGDGVGLSLPARAQSKQLQQRMDDIRIRGCYQTVAWSRTGSIANITPDGQNLELRFLRRSPDDGSWDLSEPTTCPFVKGLPTIPIVHLVWAGTSSPDLAVIDAVGRVSIVSFSISLNHPFPQRKWDADPTDDVHTVVGAYWLNVSPPNQQASYNVMYGPATKHGNGYTYESSFVHAGGPTHPSPAKSALLTITTHGVIRMFWSQNTNRLEETTMELESISASDELITHASFASEKKHLLLAVATTSKQLKLIRIEIQWGQASQADKATGRPPGNLSPSLIEKHLATTNWLQGGPGDSSLDISMIELSHLEVIPSVVDSTGKNTTPPMVVTARSRTPTESSYQGSQSVVDRWEAIEQKQNLPSAYEQLGGRRNSISSELPAVTQLQKIAPVTANKVVVAFQTTSFGKILVLAFADGTVEYRDRLTFEELYTTQELNKVQNLRQIGWTFADEGPCQQVAFSPTFCSMVQMGEDGKIKWNKLHYPMGDIGNSMQDAQYCGSIAALTVTAAPSMFYQNNYDDLLAIVRPYTTKKRFVQDLVTELIRILKIQIDYSEEIHHDSLVRNGSLQYCLSIMNALGFRGDFHPRSFQGKFSMLFLNVRNVVVLITIASNTPVTVREKLSPLDDPEVIETLVGCARWALDLIAWLMDCLFELMNDNHFQELLTRERFHELTPYLHEKNNVAFHFLMSSSSRGFLSAICRRLAHLEALSGRAIEFYRKQSAVVEGVAGGRAAPQLQQAYQAMQQVTSSALVKVSEVETLLTGLSNEIRQAYQIFLPSLAKSQNNQTQGKQLDMAMKAARVQMELSILLSAAPPAPFLQIIKKFFNTDLPAFRNTVDPGRLFFANYDLLEVEDDEHSLAAKKARGMVYVDVFKRMQIRPSPDKQWRRCSRCTAVMEDVFGSRSGFTFVLGQQRKCSCGGQWTLLPKGHVS
Length946
PositionTail
OrganismGibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) (Bakanae and foot rot disease fungus) (Fusarium fujikuroi)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Nectriaceae> Fusarium> Fusarium fujikuroi species complex.
Aromaticity0.08
Grand average of hydropathy-0.211
Instability index45.78
Isoelectric point6.45
Molecular weight105336.87
Publications
PubMed=23825955

Function

Annotated function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32389
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     279.35|     115|     230|      26|     146|       1
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   26-  105 (113.24/65.79)	......................................................................................................................................................LSLPARAQSKQLQ.QRMD........................................................................................................................................................................................................................................................................................................................................................................................................................dirIRGCYQTVAWSRTGSIANIT.PDGQNLE..........LRF.LRRSPDDGSWDLSEPTTCPFVKGLPTIPIV
  107-  146 (22.09/14.53)	LVWAGTSSPDLAVIDAVGRVSIVSfSISLNHPFPQRkWDA...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
  257-  334 (71.46/34.73)	........................................dptddvhtvvgaywlnvsppnqqasynvmygpatkhgngytyessfvhaggpthpspaksalltitthgvirmfwsqntnrleettmelesisasdelithasfasekkhLLLAVATTSKQLKlIRIE..................................................................................................................................................................................................................................................................................................................................................................................................................................IQWGQASQADKATgRPPGNLSpsliekhlatTNW.LQGGPGDSSLDISMIE....LSHLEVIPSV
  335-  372 (30.56/ 7.92)	VDSTGKNTTPPMVVTARSRTPTES.SYQGSQSVVDR.WEA...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
  784-  834 (42.00/16.59)	........................................................................................................................................................................ieqkqnlpsayeqlggrrnsisselpavtqlqkiapvtankvvvafqttsfgkilvlafadgtveyrdrltfeelyttqelnkvqnlrqigwtfadegpcqqvafsptfcsmvqmgedgkikwnklhypmgdignsmqdaqycgsiaaltvtaapsmfyqnnyddllaivrpyttkkrfvqdlvtelirilkiqidyseeihhdslvrngslqyclsimnalgfrgdfhprsfqgkfsmlflnvrnvvvlitiasntpvtvreklsplddpevietlvgcarwaldliawlmdclfelmndnhfqelltrerfheltpylheknnvafhflmssssrgflsaicrrlahlealsgraiefyrkqsavvegvaggraapqlqqayqamqqvtssalvkvsevetlltglsneIRQAYQIFLPSLAKSQNNQT..QGKQLD..........MAMkAARVQMELSILLSAAPPAPFL.........
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32389 with Med16 domain of Kingdom Fungi
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