<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32376

Description Likely protein kinase
SequenceMNTQEHLASASTSTSASTSSTTIMSDPIRPSGYFYSDAEDPFAGAFWSQFEDPHDLAARHIPTDSSPAAAMRAYREYRDRVRKPVLATYTILGFLSSGTYGRVYKARLRTPPQVASATGSAGAANPNGGAGSGSTAGTSSSTAKKKSALLQQHQLLDSPGSSLHATPKSALDASALGANGTPTASPGVGASLAGSSANALDRSDHSAQLSGTNLPDSQIYAIKKFKPDSKETDATIYTGISQSAMREISLNRELSHINIVTLHQVMLEDKAIYMVFEYAEHDLLQIIHYHSTALRAPIPLAVLKSLLWQLINGVAYLHANWILHRDLKPANILVTSQGVVKIGDLGLARLYSSPLQSLYNGDKVVVTIWYRAPELLLGARHYTTAIDMWSVGCIWGELLALRPMFKGEEAKMDPKTKAAPFQTDQLKRIVEVLGTPNKDRWPAIESMPDYKGWWPHLRLDNYPKTLSRWYATRNKGDDGYDLFDSLLQYDPEQRLTANQALEHAWFTAQDPKPTANAFSSLTKPLATYPNRRVIQDDMDPKMKSNYLPPIERHHIQPSHQYNLNSSQPHRLAQLMFQQEQLRHQQMQQQKQPSQSQQPSARNNAPGTAVVPVAPIVGGPAAPPPITIGSGAAGGGGAGAGMQSSAPSSGAGGNNPVITIAGTSGATVSNPASVKSTHSIGSIETSTPTTATGSTARNNLVATATRNQQRKRQRI
Length714
PositionKinase
OrganismPseudozyma hubeiensis (strain SY62) (Yeast)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina> Ustilaginomycetes> Ustilaginales> Ustilaginaceae> Pseudozyma.
Aromaticity0.07
Grand average of hydropathy-0.428
Instability index49.68
Isoelectric point9.35
Molecular weight77083.72
Publications
PubMed=23814110

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32376
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      94.14|      21|      25|     632|     652|       2
---------------------------------------------------------------------------
  121-  143 (21.54/ 8.29)	AGAanpnGGAGSGSTAGTSSSTA..
  632-  652 (38.18/21.08)	AGG....GGAGAGMQSSAPSSGAGG
  660-  680 (34.42/18.19)	AGT....SGATVSNPASVKSTHSIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      29.77|       9|      25|     365|     376|       3
---------------------------------------------------------------------------
  365-  376 (11.58/11.47)	VVTIWyraPELL
  391-  399 (18.19/ 8.53)	VGCIW...GELL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     107.57|      26|      26|     158|     183|       4
---------------------------------------------------------------------------
  158-  183 (44.48/24.74)	SP..GSSLHATPKSALDASALGANGTPT
  185-  212 (36.75/19.18)	SPgvGASLAGSSANALDRSDHSAQLSGT
  214-  234 (26.34/11.70)	LP..DSQIYAIKKFKPDSKETDA.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.40|      24|      27|     545|     568|       5
---------------------------------------------------------------------------
  545-  568 (44.71/26.52)	NYLPPIERHHIQPSHQYNLNSSQP
  569-  592 (42.69/25.02)	HRLAQLMFQQEQLRHQQMQQQKQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.54|      13|      26|     440|     453|       6
---------------------------------------------------------------------------
  440-  453 (23.82/14.04)	RWPAIESMPDyKGW
  468-  480 (26.72/11.45)	RWYATRNKGD.DGY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32376 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ARLRTPPQVASATGSAGAANPNGGAGSGSTAGTSSSTAKKKSALLQQHQLLDSPGSSLH
2) YPNRRVIQDDMDPKMKSNYLPPIERHHIQPSHQYNLNSSQPHRLAQLMFQQEQLRHQQMQQQKQPSQSQQPSARNNAPGTAVVPVAPIVGGPAAPPPITIGSGAAGGGGAGAGMQSSAPSSGAGGNNPVITIAGTSGATVSNPASVKSTHSIGSIETSTPTTATGSTARNNLVATATRNQQRKRQRI
106
528
164
714










Molecular Recognition Features






MoRF SequenceStartStop




1) IYAIKKF
219
225