<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32354

Description CMGC/CDK/CDK8 protein kinase
SequenceMPAGGYTSKRRVMERYKIIGFISSGTYGRVYKAQGKNGIVGEFAIKKFKPDKEGEPQYTGLSQSAIREMALCTELSHLNVVSTREIILEDKCIFIVFEYAEHDLLQIIHHHTTPQRHCIPAPTIRSILWQLLNGLLYLHRNWVMHRDLKPANIMVTSAGSVKIGDLGLARLFFKPLQSLYMGDKVVVTIWYRAPELLLGSRHYTPAIDMWAVGCIFAELLSLRPIFKGEEAKMDAKKQVPFQRNQMLKIAEVLGVPNVKQWPLLSSMPEYSQLSTLSAGGNSRVHRPIGLENWYNGVLKQNGYPPVEKSPTGEKKAAENPGPEGLDLLKALLTYDPQQRITAEQALQHKYFTTGEKPSMNCFEGITTKYPSRRVSQEDNDIRTGSLPGTKRSGLPDDSLRPTKRLKEG
Length408
PositionKinase
OrganismConiosporium apollinis (strain CBS 100218) (Rock-inhabiting black yeast)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes> Dothideomycetes incertae sedis> Coniosporium.
Aromaticity0.08
Grand average of hydropathy-0.377
Instability index45.43
Isoelectric point9.41
Molecular weight45962.63
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32354
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.22|      17|      85|     162|     178|       2
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  148-  165 (24.22/14.15)	LKPANIMVTSAGSvKIGD
  166-  183 (26.00/15.65)	LGLARLFFKPLQSlYMGD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     123.08|      37|      90|      91|     132|       3
---------------------------------------------------------------------------
   91-  132 (55.57/50.19)	KCIFIVFeYAEHDLLqIIHHHTTPqrhCIPAPTIRSILWQLL
  184-  220 (67.51/41.86)	KVVVTIW.YRAPELL.LGSRHYTP...AIDMWAVGCIFAELL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32354 with CDK8 domain of Kingdom Fungi
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