<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32329

Description Uncharacterized protein
SequenceMADRLTQLQDAVNQMADHFCNAVGIMQQMAPPGQFAGFEKSVSKQAQVTSDEHAALFAQLIARTAKDIDVLIDSLPSEESTPELQMASLLQLEQDNQEAAQELQHAVDHGTLVLQSTQSAMHSIAQAQLDSQALETQDAFASVGPLPEEEMDGQSQYSDVTNDGCL
Length166
PositionMiddle
OrganismCapitella teleta (Polychaete worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Annelida> Polychaeta> Sedentaria> Scolecida> Capitellidae> Capitella.
Aromaticity0.04
Grand average of hydropathy-0.337
Instability index53.43
Isoelectric point4.05
Molecular weight17943.60
Publications
PubMed=23254933

Function

Annotated function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. 
GO - Cellular Component
mediator complex	GO:0016592	IEA:UniProtKB-UniRule

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32329
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.15|      16|      19|      83|     101|       2
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   83-   99 (23.54/17.49)	ELQMA...SLLQLeQDNQEA
  102-  120 (22.61/ 6.72)	ELQHAvdhGTLVL.QSTQSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.74|      15|      16|     129|     143|       3
---------------------------------------------------------------------------
  129-  143 (22.95/11.16)	LDSQALETQDAFASV
  146-  160 (25.79/13.23)	LPEEEMDGQSQYSDV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32329 with Med21 domain of Kingdom Metazoa
Unable to open file!