<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32322

Description Uncharacterized protein
SequenceMQCTPQDLKERLLKAVDQDHNVVNMAEVLDVFSFLERHTISREILEQTRMGLTVNNIRRQTSNKDLAKRARALLRAWQKLLPSTQPTVNGDAHNTGNGSVLHRNVNSLVNSAESKPNSPVSRPGTPGLSHRRPGTPASSSTHAANTPLSSFHKSRLSPKSAIATGVSSPVLSQPSPSASSSPHLTSSTPHAANACISRSSTPTEALSKKNVANKRKRRVDSPLAEGREVKHNNYPKNTSCDNDAESGGIKLTIKHDRMNGLVSHTDIFKNGASSSTDEAHPPPFKRTVSSSSLKLEEAHELRGTPGPSLERVQSASALAMASRTPKVKTTMQLMKELHESGVKLRSSETITKIALNQIQKEDDSDQMSVVPAGAKPRPRKKPAMLPPTPSHRTLSQTKEERIQKFLQTSISAGSDADLNALLHLDPPLELDASQSQADVKRCHEERFADLERRELNSAEPCEDDELAVEVERPADEKQRFLDDPWSFLPALDLNTIDFEDDQYYIADEDVQERSTVTPNMVSRLTESNWAGVNGQFDHEDRWHDWVAAYSLPSFQGQMLHLLPYVDLEESQRSNDSEVKGEEDEGGGEVGADGVL
Length595
PositionUnknown
OrganismCapitella teleta (Polychaete worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Annelida> Polychaeta> Sedentaria> Scolecida> Capitellidae> Capitella.
Aromaticity0.04
Grand average of hydropathy-0.753
Instability index55.36
Isoelectric point6.05
Molecular weight65475.01
Publications
PubMed=23254933

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP32322
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     163.07|      47|      48|      92|     139|       1
---------------------------------------------------------------------------
   82-  132 (75.28/41.27)	P...STQPTVngdAHNTGNGSvLHRNVNS.LVNSAESKPNSPVSRP.GTP..GLSHRR
  133-  175 (57.34/27.20)	P...GTPASSsthAANTPLSS.FHKSRLS.........PKSAIATGvSSP..VLSQPS
  176-  209 (30.45/11.35)	PsasSSP......................hLTSSTPHAANACISRS.STPteALSKK.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     289.44|      88|     135|     355|     445|       2
---------------------------------------------------------------------------
  355-  445 (141.71/81.82)	LNQIQKEDdsDQMSVVPAGAKPRPRKKPAMLPP.TPSHRTLSQTKEERIQKFlQTSISAGSDADLNA.LLHLDPPLELDASQSQADVKRCHEE
  493-  582 (147.72/77.08)	LNTIDFED..DQYYIADEDVQERSTVTPNMVSRlTESNWAGVNGQFDHEDRW.HDWVAAYSLPSFQGqMLHLLPYVDLEESQRSNDSEVKGEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.22|      16|      21|     277|     292|       3
---------------------------------------------------------------------------
  277-  292 (30.87/16.54)	DEAH.....PPPFKRTVSSSS
  296-  316 (19.34/ 7.86)	EEAHelrgtPGPSLERVQSAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.35|      18|      21|      35|      52|       4
---------------------------------------------------------------------------
   35-   52 (29.05/23.81)	LERHTISREILEQTRMGL
   57-   74 (27.31/21.88)	IRRQTSNKDLAKRARALL
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP32322 with Med26 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) ETITKIALNQIQKEDDSDQMSVVPAGAKPRPRKKPAMLPPTPSHRTLSQTKEERIQKFLQTS
2) GLVSHTDIFKNGASSSTDEAHPPPFKRTVSSSSLKLEEAHELRGTPGPSLERVQSASALAMASRTPKVKTTMQLMKELHESGVKLRS
3) QKLLPSTQPTVNGDAHNTGNGSVLHRNVNSLVNSAESKPNSPVSRPGTPGLSHRRPGTPASSSTHAANTPLSSFHKSRLSPKSAIATGVSSPVLSQPSPSASSSPHLTSSTPHAANACISRSSTPTEALSKKNVANKRKRRVDSPLAEGREVKHNNYPKNTSCDNDAESGGIKLTIKHD
348
260
78
409
346
256

Molecular Recognition Features

MoRF SequenceStartStop
1) KPRPRKKPAML
2) LLPYVDLEESQR
375
561
385
572