<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32306

Description Uncharacterized protein
SequenceMATFISQEQRPLKKPRLGAVGPDVYPQDLKQKEDELTTSSVKHGFNNPPVISDEHGSAKNYNINPSKFISFYNGVITKKADLDMYQDQAKRKPQINHKDIFYPVISKTKGAVEAWIKDLAAGVKSLAQLGKKVPIFNKKEDVLTTLCDSKVSMMRACWFIKMTNVYNMAMADATKAKKRHTVYDPFNEWTMVITRHLREQLVKIIEHYQGNVTGTSFLTAGPTSVVDLECPMKNWNYCTNLARYMYEEGLLDQHELLSWFLELLEKQKITDDTVLKLIFAQVMKYTSDFVQSQLLSRKLTHFCARKLSQFCNESSCSSAPRSNSPVVSQSSNANSRSGSATPSHSQHPISSLFAEYNGCPQHRGLILALSYVLQTVAIRCPGALVWHHLGDGKGSSILSGSPLDLLPCAPSCLPMAPGADNQSIRSQIRAAENQIAARGRSAEMKWSSDKCQRTNSGSVISHVLHVLEALDQHNFDRVEANSSLDSLYHRVFSSVHCKDNGSSNMIGDEPVVNLLCEWAVSTQRTGEHRAIVVAKLLEKRQNELASEKFSDPSEMADERDHSVTSGSEMMGLGSGGSAPFQALLMNFLDKKAPLLDDNPTVENKSAFANLILLFCELISNEVFSHDAYICTLISRGDLMQYPSVMPSTSIMASLYHANPDVDLSSVKSESMKQEVSHRGHTPGLAHTPGSSRLSHMPLSVPMSRDSCRHLVYVTHFPIPQDDLYSHECNQRQVLLYGVGKARDEARHIVKKITKEVLKLFSKKNCIEIVNGDSKQNKRKKEKEVFDTVNYEAIFHKFHKLSYYDQHALTSAVSNTIVESFSAFAAGTSVYLPQIENISFLLDLMEFCNHINGLLDFLTLVLKELPDVESQLHQKGSLHASGLFSTNLCLFFVALLRKYHAYLLVSTENTCVVFESLCRVVKHVANPAGCSSSERCILAYLYDVYTKCNFLKLRYGELFGSACLKVQSTVYARVSPTPTNLLWDTAFMSDAFHNPKMKIDQMTAKQINDNPNDRYNFVVNAVLNVCLSGTTSLLRLNDVSILCAEMTGFCNSLSSEWLGVLKALCWSSNHNCGYIDVIARNDINDLSLHDNLAVFTAILVAHHCFTLEDLVSHVALHSLLAACPSRGDQAAEKGARLTCHLLLRLFQSVHVLPGSSPETRKNVLGIKSSCDRHLLEAAHNSITVGAVVAVLKAILMLDSCNSDSRNLKKDGSDDIISSMLSSLDDGMDDLSIGILGRCVALVSLQQAAGLSEYAKHCLKEICSQEWVREKLLKNPENLFDSDLLLDNMLSQRQAQQLVQMICYPGGIPSVLPLDEDDEDEEPEEQRHITRILQNVDLWSLRVSWLELQLMLKQASNSEMSGLIENIAIATIEVFQRQTERKNKLLDNAVASPSNPWHEKENESAWLIAPLISKLSSSVQGKVLRTAGQVLETGNNFWSAKNSKDRERYLLKSTSLLGHQPFLSLVFACLQGQDEQREGLLKSLYDQLDKFVTNTKEQQDRGMPTEDKLKFMMQEALQLRLSLVGGMFDTIQRSNNLRQDWAILLMQLVSHGVVDINNNSELFTIVLDMLSVLIHGTLVSENSDIKGEDNRKHYQQLIRKLKKELGEKHSASIDQCRQLLPLPKLLSEVLQCEPFESDSESNRHKGTANYHDRRAEEGLKICNKQKVSPWEMIEGMKSLTPFSLAWFGAVRLERQPVSFEDEHHRLMYHSHHLKKPVSHFLDAPQLPAEDLEPIAQEKPVGFTFPHNSPILEHVLDGKHPQDKNSKPKRRGSNRRQSPRIGTPTGHSPYMPGPMAGPMGFQRQDMYAQGGQGHNWYPGQNSRPPQQQQQQGQYMQGPPQHLPPGGPRFGPGASISSSSKMALSSYLRARNPNPNYMPQQNPTQNYENMRLMQQEQHQRMIRHRLSSMQNQRNMINRMGSNDGAAYAQQMGNFPPQPMPAQRGYNQGMGGGMGGSQQPGGPQQQPPPQTFNQPFQGSSTSGGGMVGRMPGMAAGGQPPGGPGGYMGQQQGPPLPQSQQYPNTSRFSGMEVGNLSAGAGGMQGGAQSALSMSGGGLSQMPGQYNPQGPQAGYNMQAGGSSGMAAPPNTAGLTQQQRQQVQQRQQMMMQQQQQQHQQQQMQPQMGAATPQQSMYPQMQRQLSGGGGGGNNFNPYQQQY
Length2153
PositionKinase
OrganismCapitella teleta (Polychaete worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Annelida> Polychaeta> Sedentaria> Scolecida> Capitellidae> Capitella.
Aromaticity0.07
Grand average of hydropathy-0.441
Instability index50.01
Isoelectric point7.66
Molecular weight239480.56
Publications
PubMed=23254933

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32306
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     249.06|      25|      25|    1783|    1807|       1
---------------------------------------------------------------------------
 1783- 1801 (34.34/11.93)	...................GHSPYMPG......PMA.G...PMG...FQR.Q
 1802- 1828 (37.27/13.56)	D....MYAQG.......gqGHNWY.PG......QNSrP...PQQ...QQQ.Q
 1904- 1926 (25.95/ 7.27)	S....MQNQR.........NMINRMGS......NDG.A...AYA...QQ...
 1934- 1961 (41.96/16.17)	P....MPAQR.........GYNQGMGG......GMG.GsqqPGG...PQQ.Q
 1965- 2004 (29.58/ 9.29)	Q....TFNQPfqgsstsggGMVGRMPGmaaggqPPG.G...PGG...YMG.Q
 2043- 2068 (27.10/ 7.91)	S....ALSMS........gGGLSQMPG......QY..N...PQG...PQAgY
 2100- 2133 (25.76/ 7.17)	QmmmqQQQQQ.........HQQQQMQP......QMG.A.atPQQsmyPQM.Q
 2134- 2152 (27.10/ 7.91)	R....QLSGG.........G..GG..G......NNF.N...PYQ...QQ...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.78|      22|      98|     822|     848|       2
---------------------------------------------------------------------------
  826-  848 (35.33/32.12)	GTSVYLpQIENISFL.LDLMEFCN
 1028- 1050 (34.45/15.69)	GTTSLL.RLNDVSILcAEMTGFCN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.50|      23|     106|      17|      41|       3
---------------------------------------------------------------------------
   17-   41 (31.96/31.41)	LGAVGPDVyPQdLKQKEDELTT...SSV
  126-  151 (34.54/21.94)	LAQLGKKV.PI.FNKKEDVLTTlcdSKV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     410.88|     102|     107|    1565|    1667|       4
---------------------------------------------------------------------------
 1449- 1560 (123.25/76.85)	LKSTSLLGHQPFLSLVfACLQGQDE..QR..EGLLKSLYDQLDKFVTNTKEQQDRGMPtedkLKFM....MQEALQlrlslvGGM....FDTIQRSNNlR..QDWAILLMQLVSHGVvDINNNSEL.
 1565- 1666 (165.71/107.58)	LDMLSVLIHGTLVSEN.SDIKGEDN..RKHYQQLIRKLKKELGEKHSASIDQCRQLLP....LPKL....LSEVLQ......CEP....FESDSESNR.H..KGTANYHDRRAEEGL.KICNKQKVS
 1677- 1775 (121.93/75.73)	LTPFSLAWFGAVRLER.QPVSFEDEhhRLMYH..SHHLKKPVS..H.........FLD....APQLpaedLEPIAQ......EKPvgftFPHNSPILE.HvlDG.KHPQDKNSKPKR.RGSNRRQ.S
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     320.30|      99|     106|     303|     408|       5
---------------------------------------------------------------------------
  307-  408 (163.91/129.72)	LSQFCNESSCSSAPR.SNSPVVSQSSNANSR..SGSATPSHSQHPISSLFAEYNGCPQHRGLILALSYVLQTVAIRCPGALvwhHLGDGKGSSILSGSPLDLLPC
  415-  516 (156.39/103.99)	MAPGADNQSIRSQIRaAENQIAARGRSAEMKwsSDKCQRTNSGSVISHVLHVLEALDQHNFDRVEANSSLDSLYHRVFSSV...HCKDNGSSNMIGDEPVVNLLC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     304.00|      95|     196|     855|     960|       6
---------------------------------------------------------------------------
  580-  638 (88.81/65.06)	FQALLMNFLDKKAPLLDDNPTVENKSAF.ANLILLFCE.........LISNE....VF.......SHDAY.....ICTLISRGDL...........................
  856-  960 (144.52/159.86)	FLTLVLKELPDVESQLHQKGSLHASGLFsTNLCLFFVALLRKYHaylLVSTEntCVVFESLcrvVKHVANP...AGCSSSERCILAYLYDVYTKCNFLkLRYGE....LFGS
 1094- 1154 (70.67/52.36)	...................................FTAILVAHH..........CFTLEDL...VSHVALHsllAACPS..RGDQAAEKGARLTCHLL.LRLFQsvhvLPGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     131.58|      42|     285|    1051|    1093|       7
---------------------------------------------------------------------------
 1051- 1093 (73.06/59.56)	SLSSEWLGVLKALCWSSNHN.CGYIDVIARNDINDLS........LHDNlAV
 1338- 1388 (58.52/41.82)	SLRVSWLELQLMLKQASNSEmSGLIENIAIATIEVFQrqterknkLLDN.AV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32306 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PHNSPILEHVLDGKHPQDKNSKPKRRGSNRRQSPRIGTPTGHSPYMPGPMAGPMGFQRQDMYAQGGQGHNWYPGQNSRPPQQQQQQGQYMQGPPQHLPPGGPRFGPGASISSSSKMALSSYLRARNPNPNYMPQQNPTQNYENMRLMQQEQHQRMIRHRLSSMQNQRNMINRMGSNDGAAYAQQMGNFPPQPMPAQRGYNQGMGGGMGGSQQPGGPQQQPPPQTFNQPFQGSSTSGGGMVGRMPGMAAGGQPPGGPGGYMGQQQGPPLPQSQQYPNTSRFSGMEVGNLSAGAGGMQGGAQSALSMSGGGLSQMPGQYNPQGPQAGYNMQAGGSSGMAAPPNTAGLTQQQRQQVQQRQQMMMQQQQQQHQQQQMQPQMGAATPQQSMYPQMQRQLSGGGGGGNNFNPYQQQY
1743
2153










Molecular Recognition Features






MoRF SequenceStartStop




1) SMYPQ
2127
2131