<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32300

Description "Cyclin-dependent kinase E-1, CDKE-1"
SequenceMFGPSRGRPTQQLRISEKYASVGKIGEGTYGLVYKARHVQSSPGSAVGDPSSRAESFVAVKRFKSFKSGDGISPTAIREIKLLRELKNRYIVDLVDVMLDEADKALYLVFDYAEHDLLEMIRWHHNRASQPMQMPTVKSLLWQILHGMNYLHKNWIIHRDLKPSNILVTGQDKPPNERGCVKIADFGLARLFQAPLRPLTDVDAVVVTIWYRAPELLLGAKHYTKAIDLWAIGCIFAELITSKPLFQGQEKERKGDDRNPFQADQIDKIFRILGKPTLEQWPGAADLPNWTHAQSWQAYPCVLHERIRGLPKNSAGYDLLSKLLEYDPNKRITAENALRHPFFQEEPRPQRVAFIDPNVDPYKSRPVTPLDPKKDIGWAMSATASGSNGQTPMTRSIPQSAAPSLTSAPPPSKRAKKVAS
Length420
PositionKinase
OrganismChondrus crispus (Carrageen Irish moss) (Polymorpha crispa)
KingdomRhodophyta
LineageEukaryota> Rhodophyta> Florideophyceae> Rhodymeniophycidae> Gigartinales> Gigartinaceae> Chondrus.
Aromaticity0.09
Grand average of hydropathy-0.454
Instability index38.73
Isoelectric point9.52
Molecular weight47260.72
Publications
PubMed=23503846

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:EnsemblPlants

GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
kinase binding	GO:0019900	IEA:EnsemblPlants
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32300
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.48|      29|      94|     235|     267|       1
---------------------------------------------------------------------------
  235-  267 (41.95/36.22)	IFAELITSKPLFqgQEKERkgDDRNPFQADQID
  332-  360 (53.54/32.02)	ITAENALRHPFF..QEEPR..PQRVAFIDPNVD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     163.94|      52|     356|       4|      55|       3
---------------------------------------------------------------------------
    4-   55 (89.82/59.06)	PSRGRPTQQLRISEKYA.SVGKIGEGTYGLVYKARHV.QS.SPG.SAVGDPSSRAE
  361-  416 (74.11/47.43)	PYKSRPVTPLDPKKDIGwAMSATASGSNGQTPMTRSIpQSaAPSlTSAPPPSKRAK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32300 with CDK8 domain of Kingdom Rhodophyta


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AFIDPNVDPYKSRPVTPLDPKKDIGWAMSATASGSNGQTPMTRSIPQSAAPSLTSAPPPSKRAKKVAS
353
420










Molecular Recognition Features






MoRF SequenceStartStop




1) PSKRAKKVAS
411
420