<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32287

Description Mediator complex subunit 23
SequenceMRKGLPSARGGVPVPLIMAVPMETQLQSIFEEVVKTEVIEEAFPGMFMDTPEDERTKLISCLGAFRQFWSNLSQESHEQCIQWIVRFIHSQHSPKRISFLYDCLAMAVETGLLPPRMVCESLLNSDNLEWERTQLWSLTFKLVQKIIGGVDYKGVRDLLKGILEKILTIPNTVSSAVVQQLLAAREVVAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDSFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPTTLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQTLNIAQHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAHSDNSKLQIPIPHSLKLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGVLVETIYGNGNMRTPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSLALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSNLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLNEPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMNFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMTIENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHIRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMSYHKKYPEKLYFEGLAEQVNPPVQTQSQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEGHLRERPSLKRKLVHSIIGSLKDNRPQGWCLSETYLKCAMNAREDNPWIPDDIYYCKLIARLVDTMAGKSPSPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKEVGNALLNVVLKSQPLVPRDNITAWMNAIGLIITALPEPYWIVLHERIVSVINSPSLTSETEWVGYPFQLFDFTACHQSYSEMCCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLIPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMLEIGVAFYEMLLEVDQCNTHLNYMDPICDFLYHVKYMFTGDSVKDQVEKIICNLRPALKLRLRFIHISKMDSASVPQQSISTVSPASQPPQVPVNIALPVSQ
Length1396
PositionTail
OrganismAnolis carolinensis (Green anole) (American chameleon)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Lepidosauria> Squamata> Bifurcata> Unidentata> Episquamata> Toxicofera> Iguania> Dactyloidae> Anolis.
Aromaticity0.10
Grand average of hydropathy-0.014
Instability index47.31
Isoelectric point7.18
Molecular weight159563.77
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
transcription regulator complex	GO:0005667	IBA:GO_Central

GO - Biological Function
GO - Biological Process
positive regulation of gene expression	GO:0010628	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32287
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.44|      18|      19|    1032|    1049|       1
---------------------------------------------------------------------------
 1030- 1047 (34.53/21.60)	TYLYNTLHYYEGHLRE.RP
 1048- 1066 (24.92/13.54)	SLKRKLVHSIIGSLKDnRP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.39|      17|      19|     265|     283|       2
---------------------------------------------------------------------------
  265-  283 (28.00/25.33)	DPTT..LRFPLKglLPYDKDL
  285-  303 (28.39/17.77)	EPQTalLRYVLE..QPYSRDM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.61|      24|      89|    1094|    1119|       3
---------------------------------------------------------------------------
 1094- 1119 (43.58/31.81)	YYCKLIARLVDTMagKSPSPFPNCDW
 1187- 1210 (44.03/25.76)	YWIVLHERIVSVI..NSPSLTSETEW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.61|      17|      19|     921|     938|       4
---------------------------------------------------------------------------
  921-  938 (26.11/23.31)	NDFRNRVSDFVKEnSPEH
  942-  958 (34.51/25.33)	NDWHTKHMSYHKK.YPEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.17|      27|      89|    1211|    1240|       5
---------------------------------------------------------------------------
 1211- 1240 (49.67/41.65)	VGYPF..QLFDFTAC..HQSYSEMCCSYtlaLAH
 1297- 1327 (43.50/28.17)	IGVAFyeMLLEVDQCntHLNYMDPICDF...LYH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.83|      19|      21|     842|     861|       6
---------------------------------------------------------------------------
  842-  861 (27.25/26.75)	GARALVAHIRTFADfLVYEF
  866-  884 (35.58/28.37)	GGQQLNKCIEILND.MVWKY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.37|      25|      81|     405|     439|       7
---------------------------------------------------------------------------
  192-  218 (39.44/19.75)	LERNAclLPAYFAVTEIRK.LYPEGK.LP
  411-  437 (35.93/33.08)	IQKNA..LADFLPVMKLFDlLYPEKEcIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     188.03|      65|      79|     474|     552|       9
---------------------------------------------------------------------------
  474-  552 (109.06/105.05)	IPHSLKLHHEF.LQQSLRNKSLQMNDYKIAL.LCNAystnsecftlpmgvLVET.....IYGN.......GNMRTPLPGT.NCMASGSI.TPLPM
  554-  634 (78.97/52.48)	LLDSLTVHAKMsLIHSIATRVIKLAHAKSSLaLAPA..............LVETysrllVYMEieslgikGFISQLLPTVfKSHAWGILhTLLEM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.35|      15|     789|     103|     119|      10
---------------------------------------------------------------------------
  103-  119 (25.68/24.22)	CLAMAVETGllPPRMVC
  895-  909 (29.67/20.51)	CLAMRSHEG..NEAQVC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.82|      12|      20|     378|     389|      11
---------------------------------------------------------------------------
  378-  389 (21.06/11.40)	HMVLSLHQKLAG
  398-  409 (22.76/12.91)	HLMWVLLQFISG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.88|      27|     293|     964|     990|      12
---------------------------------------------------------------------------
  964-  990 (51.39/33.75)	LAEQVNPPVQTQSQYLPIY..FGNVCLRF
 1258- 1286 (43.50/27.33)	LTEVLIPIVKTEFQLLYVYhlVGPFLQRF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     159.00|      34|     684|      50|      83|      14
---------------------------------------------------------------------------
   50-   83 (62.87/34.05)	TPEDERTKLISCLGA.FRQF....W..SNLSQESH........EQCIQW
  750-  794 (45.08/22.49)	TPHNWASHTLSCFPApLQAF....FkqNNVPQESRfnlkknveEEYRKW
  798-  835 (51.05/26.37)	TIENDIITHFSMQGS.PPLFlcllW..KMLLETDH........INQIGY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32287 with Med23 domain of Kingdom Metazoa
Unable to open file!