<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32245

Description ATP-dependent DNA helicase
SequenceMAASKTPGRGAVVASYGSDADDGRVKHTGVDPATDSMESEAIQEELQNLDVELKDVQGQISALIEHQDKLYERKSELKTLLKALAASGSPVASSGGSSAVENWSEAFEWDSRADDVRFNTFGISTYRANQKEIINAIMSGRDVLVIMAAGGGKSLCYQLPAILRGGTTLVVSPLLSLIQDQVMGLAALGISAYMLTSTSGKENEKFVYKALEKGEDDLKILYVTPEKVSKSKRFMSKLEKCHNAGRLSLISIDEAHCCSQWGHDFRPDYKNLSILKTQFPKVPMVALTATATQKIQNDLIEMLHIPKCVKFVSSVNRPNLFYSVREKSAVGKVVVDEIADFIRESYSNNESGIVYCFSRKECEQIAGDLRERGISADYYHADMDVNMREKVHMRWSKNKLQVIVGTVAFGMGINKPDVRFVIHHSLSKSMETYYQESGRAGRDGLPSECILFFRSADVPRQSSMVFYEYSGLRNLYDIVRYCQSKTKCRRSAFFRHFGEPSQDCNGMCDNCALSSEVEEVDVSDLAKLVVSMVQEMQAKDQRVTMLQLGDKLRNKHKDLSAELKRDEIEHLVIKLIVDSVLKEEFQHTPYSTNAYVTMGPLANQLLQGRKTIKMESSSKQIKKSKRSISFSGLELKLDELRKEISAADGNILPHTVLSTQQIGSISSQKPDSLQELEKIIGKLKTEKYGDRILEEVKRHDAVSEQLVEDPAKGETCKSRSRKRAKTENEVVLLDEEDA
Length738
PositionUnknown
OrganismCapsella rubella
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Brassicales> Brassicaceae> Camelineae> Capsella.
Aromaticity0.06
Grand average of hydropathy-0.407
Instability index42.15
Isoelectric point6.63
Molecular weight82452.06
Publications
PubMed=23749190

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:InterPro
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro
GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro
DNA repair	GO:0006281	IEA:InterPro
DNA replication	GO:0006260	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP32245
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     218.64|      72|     300|     273|     353|       1
---------------------------------------------------------------------------
  273-  353 (104.38/80.09)	SILKTQFPKVPMVALTATATQKIQNDLiemLHIPKCVKFVSSVNRPNlfYSVREKSAVG.KVVVDEIadfiRESYSNNESGI
  579-  651 (114.26/65.80)	SVLKEEFQHTPYSTNAYVTMGPLANQL...LQGRKTIKMESSSKQIK..KSKRSISFSGlELKLDEL....RKEISAADGNI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.39|      27|     220|     182|     230|       3
---------------------------------------------------------------------------
  121-  147 (47.38/25.44)	FGISTY.......RANQKEIINAIMSGRDVLVIM
  188-  221 (39.01/48.42)	LGISAYmltstsgKENEKFVYKALEKGEDDLKIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.25|      16|      20|       5|      20|       4
---------------------------------------------------------------------------
    5-   20 (27.32/19.73)	KTPGRGAVVASYGSDA
   26-   41 (27.93/20.35)	KHTGVDPATDSMESEA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.71|      10|      40|     452|     461|       7
---------------------------------------------------------------------------
  452-  461 (19.53/13.62)	FFRSADVPRQ
  493-  502 (21.18/15.40)	FFRHFGEPSQ
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP32245 with Med34 domain of Kingdom Viridiplantae

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