<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32109

Description DEHA2F04048p
SequenceMNNLQQQPGNTNSWHAMYSVSDRQKVVQILSGTLKELQNGNYDAQKAANMAQEFEKFTFMKSQSRDEYLRLIKQKVTQLRAGIRNPANGNNMGGNNPMVNQNMGQNMGSGMGMQQQPNMNPQSNMRPQNMNFLQQQAQARQQSAAQIQAQLRNGNIANQTPSQTQPVHHIQQQQQQQPSQPPQPQQSQPPQQPQPQPNQQQLHQISNMIRNAPIPQALLSKIPNLPPNVNTWTQIFDCFQKKIIPQAAMPVIKEIHNTHLQLTLRQHQQQKINQMQSQRMNQQQHQQQHQQQPQLPQQQQQQQQPQAMNNMAGTVNNSNNNTPVMNSGNFNMNNLNPQQKQQLLRRQMQQRNSLAGQNPLMQQQGQVPSQPPQPQPQQQPSQPQQQKPQMVQSSPQNPQQSKPPNFTITPDDILKYSSDAMRLLTRLQSNGSIQPNLDQSQKESFIRKYIHHQKTTMWKQGQVTNNMTNVPNTANAGNTVNQAQVQRRLQQQTGVNSMPMQSQPQTQPSAPLSQQSPMINNMQMGNQQPMPHTQMNNQNSPMMQQRAVNTPTMPMNNNDPSAATKKQAAMGSLSALLPPLTDEMKLQLRQLIEEVSRNNVALKDVTMLLSQQDKNAVRDTVVRISQQYANVDSIISYFYIITRNVEGTKRLIQMKYMTKNIIENVQRGIYLAAPDLLEKLRSQYQKYFEYVKEQFAIRRQRMQSQQPQGQPPQQQFLNNQQRNGPIQNQIPQQQVQGMPQQQNGQTLMNIGPVNSWPNVAPPMQQRNNIGSSPMIPNSVSPIIPKQMHPFQSPASNINTAPPKQGGRAQNKKSVSGTTPGATGTSRKKSINKSISSVGGIPTPANNATTPAALANSIKTPNSIPTPQVPPTQSNKNTPAEQQSPNSQMKRAPSNAGLKITEDTVGTIFNNSEVDPKLAKRRELSDTDPLKFFYASLSNLLEIDDLAGDQQGLPTPAQSSSSTGSKIGIAKSPLSPVITSNEWTCEIKPMAITSSFKQVGTIRELTASDIVQTCADLALTEVEEFSKKGVKRENDEMDDSDDIDNLFSDKKPKVEDDDYKFMYEPVEFDEWQKFMVASMQ
Length1079
PositionTail
OrganismDebaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Debaryomyces.
Aromaticity0.04
Grand average of hydropathy-0.965
Instability index64.17
Isoelectric point9.77
Molecular weight121264.07
Publications
PubMed=15229592

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32109
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.42|      20|      21|     707|     726|       1
---------------------------------------------------------------------------
  694-  713 (31.17/ 6.21)	QFAIRRQRMQSQQPQGQPPQ
  714-  733 (35.26/ 8.13)	QQFLNNQQRNGPIQNQIPQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     622.42|      82|      82|     224|     305|       2
---------------------------------------------------------------------------
   12-  123 (86.07/19.86)	NSWHAMYSV..SD.RQKVVQI.......LSGTLKELQ.NGnydaqkaanmaqefekftfmksqsrdeYLRLI.....K...........QKVTQLRAGIRN....PANGNNM.GGNNPMV....NQN.....MG..QnmgsgmgmQQQP............................NMN....PQS
  124-  229 (96.28/23.23)	NMRPQNMNF..LQ.QQ..AQA............RQQS.AA...........................QIQAQLRNGNI...........A..NQTPSQTQPvhhiQQQQQQQ.PSQPPQ.....PQQ.....SQppQ........QPQPqpnqqqlhqisnmirnapipqallskipNLP....PNV
  230-  315 (142.59/38.51)	NTWTQIFDC..FQ.KKIIPQA.......AMPVIKEIH.NT...........................HLQLTLRQHQQ...........QKINQMQSQRMN....QQQHQQQ.HQQQPQL....PQQ.....QQ..Q........QQQP........................qamnNMA....GTV
  319-  406 (84.53/19.35)	NNNTPVMNSgnFNmNNLNPQQ............KQ..................................QLLRRQMQQrnslagqnplmQQQGQVPSQPPQ.pqpQQQPSQP.QQQKPQMvqssPQN.....PQ..Q........SKPP............................NF........
  407-  470 (62.46/12.07)	...T............ITPDDilkyssdAMRLLTRLQsNG...........................SIQPNL...................D..QSQKES....FIRKYIH.HQKTTMW.............K..Q........GQVT............................NNM....TNV
  472-  548 (76.69/16.76)	NT...............................ANAG.NT.........................vnQAQVQRRLQQQ...........TGVNSMPMQSQP....QTQPSAPlSQQSPMI....NNM.....QM..G........NQQP...................mphtqmnnqNSPmmqqRAV
  738-  795 (73.79/15.80)	.............................MP...QQQ.NG.............................Q.TL..MNI...........GPVNSWPNVAPP....MQQRNNI.GS.SPMI....PNSvspiiPK..Q........MHPF............................QSP.....AS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.07|      21|      21|     840|     860|       4
---------------------------------------------------------------------------
  817-  847 (31.23/15.31)	TTPGATGTSRKKSinksissvggIPTP.....ANNA
  848-  875 (28.84/13.55)	TTPAALANSIKTP........nsIPTPqvpptQSNK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.69|      13|      15|     639|     652|       5
---------------------------------------------------------------------------
  639-  652 (18.78/18.39)	YiITRN.VEGTKRLI
  656-  669 (19.90/13.42)	Y.MTKNiIENVQRGI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.61|      12|      21|    1024|    1035|       6
---------------------------------------------------------------------------
 1024- 1035 (21.41/14.40)	FSKKGVKRENDE
 1046- 1057 (22.20/15.19)	FSDKKPKVEDDD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32109 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QAAMPVIKEIHNTHLQLTLRQHQQQKINQMQSQRMNQQQHQQQHQQQPQLPQQQQQQQQPQAMNNMAGTVNNSNNNTPVMNSGNFNMNNLNPQQKQQLLRRQMQQRNSLAGQNPLMQQQGQVPSQPPQPQPQQQPSQPQQQKPQMVQSSPQNPQQSKPPNFTITPDDILKYSSDAMRLLTRLQSNGSIQPNLDQSQKESFIRKYIHHQKTTMWKQGQVTNNMTNVPNTANAGNTVNQAQVQRRLQQQTGVNSMPMQSQPQTQPSAPLSQQSPMINNMQMGNQQPMPHTQMNNQNSPMMQQRAVNTPTMPMNNNDPSAATKKQAAMGSLSAL
2) RLIKQKVTQLRAGIRNPANGNNMGGNNPMVNQNMGQNMGSGMGMQQQPNMNPQSNMRPQNMNFLQQQAQARQQSAAQIQAQLRNGNIANQTPSQTQPVHHIQQQQQQQPSQPPQPQQSQPPQQPQPQPNQQQLHQISNMIRNAPIPQALLSKIPNLPP
3) RQRMQSQQPQGQPPQQQFLNNQQRNGPIQNQIPQQQVQGMPQQQNGQTLMNIGPVNSWPNVAPPMQQRNNIGSSPMIPNSVSPIIPKQMHPFQSPASNINTAPPKQGGRAQNKKSVSGTTPGATGTSRKKSINKSISSVGGIPTPANNATTPAALANSIKTPNSIPTPQVPPTQSNKNTPAEQQSPNSQMKRAPSNAGLKITEDTVGTIFNNSEVDPKLAKRR
246
70
699
576
227
921










Molecular Recognition Features






MoRF SequenceStartStop




1) DDYKFMYEPVEFDEWQKFMVA
2) IRKYIHH
3) KLAKRR
4) LFSDKK
1056
446
916
1045
1076
452
921
1050