<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32075

Description Serine/threonine-protein phosphatase
SequenceMGSNSSKSAPTLQRSDTNNSTRSTRSNRSIRSRRSISSIKDSQQQQSDSQQQQEEEEEQSQSQQRPQPILSRNNSATSENPILIRRNTNETLQTPNFSDTLSPHSHSQQQQQQPGSPLSTSMNGNTISRTSTNHSIISTTSHKSSSQQSNLPLKKETTTSSLSTNSNTIDIDSLIDKLLNAGFSGKRTKNVCLKNTEIELICASAREIFLSQPSLLELAPPVKVVGDVHGQYHDLIRIFSKCGFPPKTNYLFLGDYVDRGKQSLETILLLLCYKIKYPENFFLLRGNHECANVTRVYGFYDECKRRCNIKTWKLFIDTFNTLPIAAIVAGKIFCVHGGLSPVLNSMDEIRNIARPTDVPDFGLLNDLLWSDPADTINEWEDNERGVSYVFSKVAINKFLSKFNFDLVCRAHMVVEDGYEFFNDRTLVTVFSAPNYCGEFDNWGAVMGVSEDLLCSFELLDPLDSAALKQVMKKEKQERKKST
Length482
PositionKinase
OrganismCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Candida/Lodderomyces clade> Candida.
Aromaticity0.07
Grand average of hydropathy-0.557
Instability index56.53
Isoelectric point7.09
Molecular weight54241.23
Publications
PubMed=15123810
PubMed=17419877
PubMed=24025428

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
metal ion binding	GO:0046872	IEA:UniProtKB-UniRule
phosphatase activity	GO:0016791	IDA:CGD
protein serine phosphatase activity	GO:0106306	IEA:UniProtKB-EC
protein serine/threonine phosphatase activity	GO:0004722	IDA:CGD
protein threonine phosphatase activity	GO:0106307	IEA:UniProtKB-EC

GO - Biological Process
cellular response to oxidative stress	GO:0034599	IMCGD
protein dephosphorylation	GO:0006470	IDA:CGD









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32075
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     200.62|      47|      55|       7|      55|       1
---------------------------------------------------------------------------
    7-   35 (37.53/18.07)	..............................KSAP.TLQRSDTNNSTRSTRSNRSIRSRRS
   36-   87 (58.17/35.85)	IS.SIKDSQQQQSDSQQQQeeeeeqsqsqqRPQP.ILSRN..NSAT....SENPILIRRN
   94-  131 (65.88/38.42)	TP.NFSDTLSPHSHSQQQ.....................QQQPGSPLSTSMNGNTISRTS
  132-  167 (39.04/19.68)	TNhSIISTTSHKSSSQQSN...............lPLKK.ETTTSSLSTNSN........
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32075 with Med13 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MGSNSSKSAPTLQRSDTNNSTRSTRSNRSIRSRRSISSIKDSQQQQSDSQQQQEEEEEQSQSQQRPQPILSRNNSATSENPILIRRNTNETLQTPNFSDTLSPHSHSQQQQQQPGSPLSTSMNGNTISRTSTNHSIISTTSHKSSSQQSNLPLKKETTTSSL
1
162










Molecular Recognition Features






MoRF SequenceStartStop




1) IRSRRSISSIKDSQQQQ
2) RPQPI
30
65
46
69