<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32063

Description "Chromosome 1 SCAF13627, whole genome shotgun sequence"
SequenceMTAATASPLAIRDRLLQAIDGQSNICNMVVVMEVISFLEKYPITREALEETRLGKLINDVRKKTKNEDLARRAKKLLRNWQKLIEPGKVEALSKGWYSSISSPAATLPSGKLVLELKNRNDFNNCSSLEKTSNRKRELPQLEGLAPAKLPKTSPSKYLLPTGNGGSFTDNQTHQPQERDLSRPLDNSRLSATPSSAIKPPPSALGYKPPPNSSSLLQQAASASWGQYQPSPRGSLHSPQRSKLEADVRPTVAQAQRLHSITVTSGSHTSELRPFNVFGPVSQTSGSSAGDTDANDSCPKTSGHNLHASPGSDAIRLDESGPEKGEAQKCKSGDRVAGLDGQTVEEDVKEIRLKERGLTFNPLTGQIQPCHLKESSREAAGSLGYKPQPPLSSEPSKQSPPPLLSLLQQKDLQNLSRSKIIQSYFSQRSSLLMSSDAEIFAAELKNEPSGRTRHALAPERPARDLPGISRAVATEDVRRLHTQRWPGVNGCYDTKGHWFDWTESIPLEPHGDQTRLNILPYVSLD
Length524
PositionUnknown
OrganismTetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Eupercaria> Tetraodontiformes> Tetradontoidea> Tetraodontidae> Tetraodon.
Aromaticity0.05
Grand average of hydropathy-0.701
Instability index57.85
Isoelectric point9.24
Molecular weight57337.78
Publications
PubMed=15496914

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP32063
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      99.26|      17|      19|     194|     210|       1
---------------------------------------------------------------------------
  200-  218 (31.44/12.58)	PPSA.LG.YKP.PPnsSSLLQQ
  219-  237 (22.64/ 7.25)	AASAsWGqYQP.SP..RGSLHS
  378-  392 (22.28/ 7.04)	AAGS.LG.YKPqPP.....LSS
  393-  408 (22.90/ 7.41)	EPSK.Q...SP.PP.lLSLLQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     168.17|      53|     324|     115|     193|       2
---------------------------------------------------------------------------
  136-  193 (77.73/77.26)	RELPQL.EGLAPAKLPKTSPSKYllPtGNGGSFtDNQTHQPQERDlSRPL....DNSRLSATP
  462-  519 (90.43/39.38)	RDLPGIsRAVATEDVRRLHTQRW..P.GVNGCY.DTKGHWFDWTE.SIPLephgDQTRLNILP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.82|      22|      53|     299|     322|       4
---------------------------------------------------------------------------
  299-  320 (37.63/27.26)	KTSGHNLHA.SPGSDAIRLDESG
  334-  356 (31.19/14.54)	RVAGLDGQTvEEDVKEIRLKERG
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP32063 with Med26 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) AELKNEPSGRTRHALAPERPARDLPGISRAVA
2) NNCSSLEKTSNRKRELPQLEGLAPAKLPKTSPSKYLLPTGNGGSFTDNQTHQPQERDLSRPLDNSRLSATPSSAIKPPPSALGYKPPPNSSSLLQQAASASWGQYQPSPRGSLHSPQRSKLEADVRPTVAQAQRLHSITVTSGSHTSELRPFNVFGPVSQTSGSSAGDTDANDSCPKTSGHNLHASPGSDAIRLDESGPEKGEAQKCKSGDRVAGLDGQTVEEDVKEIRLKERGLTF
3) PLTGQIQPCHLKESSREAAGSLGYKPQPPLSSEPSKQSPPPLLSLLQQ
441
123
361
472
359
408

Molecular Recognition Features

MoRF SequenceStartStop
NANANA