<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32049
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MAVLNGTDDTNTLTSLAHAGFQYPPDSAGSFPSRYRGGTKFDTSIAGLHISFSPSGCNAVTLDGEGQAQLRVMEHSYGAENGLYDENKFSAAVASLTLAFCRGCGSEFNTDDILLILKRQASPDAQISFINEVYRALGVNCNYTQENDKLMSHQYLPKCLSVQAALGFIDKYKSRNFASNVPWTILQLRHASVLYALFLQYLKGGVQAEPPDAGKISTCGKYAELFLTVRFDADAIRILLGNTKWALDLLHYVLNDLLDLADDLESLLSDQEAFAQKLKTISSLPLIILLSSMSRAFLRFICRGLRGIQAGYATAPLTGDAGVYYAEIYRTLDTSPVRIDVYEKLLAGVDSTVRHVYHGAGFGDNERPGPEKELLVNGRIPPVLVTAVSTILRQTVPALKPDIDRMAIYMGDYSWLGLGSDRRAELYRRTRDVDIIKKIPFRSTASAGSDETQSGKHNPSQVRRRCVRCCEIMCGAYPPRPQLSSRMMYKLGYVRYCICGGGWTLESDFHR |
Length | 511 |
Position | Tail |
Organism | Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes>
Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus>
Aspergillus subgen. Circumdati.
|
Aromaticity | 0.09 |
Grand average of hydropathy | -0.146 |
Instability index | 36.81 |
Isoelectric point | 7.88 |
Molecular weight | 56508.85 |
Publications | PubMed=16372010
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP32049
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 252.20| 60| 100| 179| 238| 1
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179- 238 (104.70/56.71) SN.VPWTILQL....RHASVLYALFLQYLKG...GVQAEPPD.......AGKISTCG....KYAELFLTVRFDADAIRI
282- 339 (78.07/40.73) SS.LPLIIL........LSSMSRAFLRFICRglrGIQAGYAT.......APLTGDAG...vYYAEIYRT..LDTSPVRI
364- 437 (69.44/35.55) DNeRPGPEKELlvngRIPPVLVTAVSTILRQ...TVPALKPDidrmaiyMGDYSWLGlgsdRRAELYRRTR.DVDIIK.
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