<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32014

Description MeDiaTor
SequenceMGDNTIRIKSENSFGNTAANGRFPDTPFGRRPPLVSKIDGRARILRPLRPAAMQSNQQPTTSANASGPSGARISSGNIPHSQSMPVLQSGNTANRPSTAGNPAAGRPILTLPSNTTEKHVIALNQWAEVMKSKLEKMRQKSKKALDESMKEHSTMEDLSRAREALSEMGNMYYELNRAAALKCRYNAVFDKRPLYKAVESSIQDLRQKDESAYQLFYKLQEAMDERTVIEKNIIAVSETFRQNAVHAPRVSRLSVPPPLKFSKHVEDANKGVFLAMDAVMNKTRGDLTWRFKRISHPCFRNSKSLIEVHYCARRPNSEKEFVPCMKAVIVLKYGILEDMIIGGEDEDLYNQEQILHSKRKVYREFTKSAKEIILCSPVTKFTAPTNFAQCNNYIQSYVNCFSTKCYYCKKHLRQFMPPTVVTRESSPIICHKLCLMSQVP
Length440
PositionTail
OrganismCaenorhabditis elegans
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Peloderinae> Caenorhabditis.
Aromaticity0.07
Grand average of hydropathy-0.544
Instability index55.67
Isoelectric point9.62
Molecular weight49762.70
Publications
PubMed=9851916

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP32014
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.64|      20|      74|      15|      34|       1
---------------------------------------------------------------------------
   15-   34 (39.61/27.68)	GNTAANGRFPDTPFGRRPPL
   90-  109 (37.03/25.36)	GNTANRPSTAGNPAAGRPIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.11|      26|      71|     131|     156|       2
---------------------------------------------------------------------------
  131-  156 (43.81/31.27)	KSKLEKMRQKSKKA......LDESMKEHSTME
  199-  230 (36.29/24.73)	ESSIQDLRQKDESAyqlfykLQEAMDERTVIE
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP32014 with Med27 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MGDNTIRIKSENSFGNTAANGRFPDTPFGRRPPLVSKIDGRARILRPLRPAAMQSNQQPTTSANASGPSGARISSGNIPHSQSMPVLQSGNTANRPSTAGNPAAGRPILTLPSN
2) SKLEKMRQKSKKALDESMKEHSTMEDLSRA
1
132
114
161

Molecular Recognition Features

MoRF SequenceStartStop
1) VSKIDGRARILRPLRP
35
50