<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31968

Description U-box domain-containing protein 35
SequenceMSRSPDKLALPPPPPPPPSRTVVVALSGSSKSKYVVTWAIEKFATEGNVGFKLLHIHPMITSVPTPMGNAIPISEVRDDVVTAYRQEILWQSEEMLKPYTKLFVRRKVAVEVLVIESDNVAAAIAEEVTRDSIDRIVIGGSSRSFFSRKADICSVISALMPNFCTVYVVSKGKLSCVRPSDSDGNATIREDGSERTNSSSGSSGPTSDSSDVMSSAHDSQSRPLSLPVRRMQHFPAIAGQASVPMETSSVGSDETRCMSLDAEEARDVSSINRSSTDTTSRWTPRRRDYEERKEAMSSSSSNREYGNFGTRFSWSGMGVDTTHSRASQQASNMSDALSEQSYTDNQVNLNFEVEKLRAELRHVQEMYAVAQTETFDASRKLGELNQRRLEEAIKLEELKLKEYEARELAEKEKQNFEKARRDAESMRERAEREIAQRREAERKSARDTKEKEKLEGTLGSPQLQYQHFAWEEIMAATSSFSEELKIGMGAYGAVYKCNLHHTTAVVKVLQSAENQLSKQFQQELEILSKIRHPHLVLLLGACPEQGALVYEYMENGSLEDRLFQVNNSPPLPWFERFRIAWEVAAALVFLHKSKPKPIIHRDLKPANILLDHNFVSKVGDVGLSTMVQVDPLSTKFTIYKQTSPVGTLCYIDPEYQRTGRISSKSDIYSFGMILLQLLTAKPAIALTHFVESAMDSNDEFLKILDQKAGNWPIEETRELAALALCCTELRGKDRPDLKDQILPALENLKKVAEKARNSFSGVSTQPPTHFICPLLKDVMNEPCVAADGYTYDRHAIEEWLKEHNTSPMTDSPLHSKNLLPNYTLYTAIMEWRSTR
Length835
PositionTail
OrganismArabidopsis thaliana (Mouse-ear cress)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Brassicales> Brassicaceae> Camelineae> Arabidopsis.
Aromaticity0.07
Grand average of hydropathy-0.491
Instability index50.30
Isoelectric point6.10
Molecular weight93752.99
Publications
PubMed=10617198
PubMed=27862469
PubMed=14993207
PubMed=11495788

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000250
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
protein serine kinase activity	GO:0106310	IEA:RHEA
protein threonine kinase activity	GO:0106311	IEA:RHEA
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP31968
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     250.07|      83|     137|     519|     606|       1
---------------------------------------------------------------------------
  519-  606 (133.97/117.00)	QFQQELEILSK..IRHPHLVL..LLGACPEQgALVYeYMENG.SLEDRLFQVNNSPPLPW.FERFRiawEVAA.ALVFLH.KSKPKPIIHRDLKPA
  654-  744 (116.10/83.42)	EYQRTGRISSKsdIYSFGMILlqLLTAKPAI.ALTH.FVESAmDSNDEFLKILDQKAGNWpIEETR...ELAAlALCCTElRGKDRPDLKDQILPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     116.00|      38|      39|     375|     413|       2
---------------------------------------------------------------------------
  375-  413 (55.11/38.73)	FDASRKLGELNQRRLEEAIKlEELKLKEYEARELAEKEK
  416-  453 (60.89/38.62)	FEKARRDAESMRERAEREIA.QRREAERKSARDTKEKEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.63|      15|      15|     193|     207|       3
---------------------------------------------------------------------------
  193-  207 (26.34/15.11)	SERTNSSSGS.SGPTS
  210-  225 (22.30/11.64)	SDVMSSAHDSqSRPLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.77|      19|      19|     249|     267|       4
---------------------------------------------------------------------------
  249-  267 (32.02/18.93)	SVGSDETRCMSLDAEEARD
  270-  288 (33.75/20.33)	SINRSSTDTTSRWTPRRRD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.96|      30|      40|      78|     107|       5
---------------------------------------------------------------------------
   78-  107 (51.78/38.89)	DDVVTAYRQEILWQSEE..MLKPYTKLFVRRK
  118-  149 (43.17/31.13)	DNVAAAIAEEVTRDSIDriVIGGSSRSFFSRK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP31968 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AEKEKQNFEKARRDAESMRERAEREIAQRREAERKSARDTKEKEKLEGT
2) GMGVDTTHSRASQQASNMSDALSEQSYTDN
3) PSDSDGNATIREDGSERTNSSSGSSGPTSDSSDVMSSAHDSQSRPLSLPVRRMQHFPAIAGQASVPMETSSVGSDETRCMSLDAEEARDVSSINRSSTDTTSRWTPRRRDYEERKEAMSSSSSN
409
316
179
457
345
302










Molecular Recognition Features






MoRF SequenceStartStop




NANANA