<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31965

Description U-box domain-containing protein 32
SequenceMGEIGGEELVLDVDETIFVAVAEDVERSKTTVLWAARNFSGKKICLLYVHRTARAASWTHKKLVGGSFKKHDVKVIERVEKPKVDELMNSYLQLLSETEIQTDKLCIAGQNIEECIVELIARHKIKWLVMGAASDKHYSWKMTDLKSKKAIFVCKKAPDSCHIWFLCKGYLIFTRASNDDSNNRQTMPPLVQLDSDNETRKSEKLESSYMRRRLRYWRSLLEQDGEKDTGQLEREKVEPRAPPLFSSGSSSSFGEPVGPEPVSPELVDSDTLNTSNVEEKEREGDVARKVHRYDKAMHDIGQSDRTVYGEAGKKWEEDASTTEALCKAKALEGLCIKESSQRKRLEELLEKEKLEVKMVIEQNNGFMKELQMVQGRNLKLESQMRKLQDLEKEHGEKFDTAMELLKSFRQKRDEIRIDHENAVKEVNALRRLVKGETGESSGSEMLDYSFMEINEATNEFDPSWKLGEGKYGSVYKGNLQHLQVAVKMLPSYGSLNHFEFERRVEILSRVRHPNLVTLMGACPESRSLIYQYIPNGSLEDCFSSENNVPALSWESRIRIASEICSALLFLHSNIPCIIHGNLKPSKILLDSNLVTKINDYGISQLIPIDGLDKSDPHVDPHYFVSREMTLESDIYAFGIILLQLLTRRPVSGILRDVKCALENDNISAVLDNSAGDWPVARGKKLANVAIRCCKKNPMNRPDLAVVLRFIDRMKAPEVPSSETSSYANQNVPRRPPSHYLCPIFQEVMKDPLIAADGFTYEAEAIREWLANGHDTSPMTNLKMEDCNLIPNHALHLAIQDWQNQW
Length805
PositionTail
OrganismArabidopsis thaliana (Mouse-ear cress)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Brassicales> Brassicaceae> Camelineae> Arabidopsis.
Aromaticity0.07
Grand average of hydropathy-0.504
Instability index46.76
Isoelectric point6.04
Molecular weight91591.48
Publications
PubMed=11130713
PubMed=27862469
PubMed=14593172
PubMed=11495788

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000250
GO - Cellular Component
plasma membrane	GO:0005886	IDA:TAIR
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro
GO - Biological Process








Interaction





Binary Interactions
[Q94A51<-->Q84MB2: TIFY8]	NbExp=3	EBI-25519743,EBI-4426557












Repeat regions





Repeats

>MDP31965
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.94|      20|     156|      48|      90|       3
---------------------------------------------------------------------------
   68-   88 (29.53/53.64)	FKKHdVKVIERVEKPKVDELM
  500-  519 (34.41/ 6.70)	FERR.VEILSRVRHPNLVTLM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.46|      12|     491|     240|     251|       5
---------------------------------------------------------------------------
  240-  251 (23.29/12.73)	RAPPLFSSGSSS
  714-  725 (21.17/10.93)	KAPEVPSSETSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      69.91|      16|      16|     384|     399|       6
---------------------------------------------------------------------------
  367-  381 (23.39/13.75)	MKELQ.MVQGRNL.KLE
  384-  399 (25.95/16.02)	MRKLQDLEKEHGE.KFD
  402-  418 (20.57/11.23)	MELLKSFRQKRDEiRID
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP31965 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KDTGQLEREKVEPRAPPLFSSGSSSSFGEPVGPEPVSPELVDSDTLNTSNVEEKEREGDVARKVHRYDKAMHDIGQSDRTVYGEAGKK
227
314










Molecular Recognition Features






MoRF SequenceStartStop




NANANA