<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31923

Description RNA polymerase II holoenzyme cyclin-like subunit
SequenceMAANYWESTQHQNWLFTKDGLGRVREELEEDNAEVVQLFPLPQPRHLATYFNQQVNRLGKRLVVRQQALATAQTYIKRFYTKVEIRRTNPYLVVATALYLACKIEECPQHIRLIVSEARSLWPDFLGLDTSKLGECEFTMISEMSSNLIVHQPYRTLTTLQQDLNLTPEDVSRAWSIINDHYMTDLPLLCPPHIIALTAILLVLVMRPMSNASGQAQPSAAGLAAASAVLAQASRPHGLPPTPGTPNPADKEKQPGARMGQIQRFGAWLSESNVDVASMIDCTQELISFYESNEQYNDKLTREQINRFVKARGLDK
Length316
PositionKinase
OrganismColletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422) (Cucumber anthracnose fungus) (Colletotrichum lagenarium)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Glomerellales> Glomerellaceae> Colletotrichum> Colletotrichum orbiculare species complex.
Aromaticity0.08
Grand average of hydropathy-0.300
Instability index53.22
Isoelectric point6.40
Molecular weight35663.36
Publications
PubMed=23252678
PubMed=30893003

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP31923
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     159.59|      52|      85|      55|     111|       1
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   55-  111 (72.60/61.71)	VNRLGKRLVVRQ..QALATAQTYIKrfYTKVEIRRTnpYLVVATAlYLACKIEECPQHI
  141-  194 (86.99/54.76)	ISEMSSNLIVHQpyRTLTTLQQDLN..LTPEDVSRA..WSIINDH.YMTDLPLLCPPHI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP31923 with CycC domain of Kingdom Fungi
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