<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31905

Description Vacuolar calcium ion transporter
SequenceMKEASPDPPNIDGSRSGAQPAAPTAQGLNEHSNTQHKEFNEKQNGSSGSVNGGDRQGPSRNNSSLLKALSAGDIPSHTASQAARPGSVIETPNKAEEPSQENPNPTSKMNRFFAEVKRSVKISIFHSWLNILLIFVPVGIAVSQVDGINGGIVFGLNAVAIIPLAGLLAYATESVARKMGDALGALLNVTFGNAVELIIFISALTKDEIRIVQASLLGMSMLLGGLRFREQVYNSTVTQMSACLLSLSVISLVLPTAFHASFQDNDLADRQSLKISRGTSIVLLLVYVIYLMFQLKSHAYMYESTPQHIIDAELAPGPAAGLLDSSSSDDSSSSSSDSSDSDSSHGTMRKKMKKVLRNRRHRRSSTASVDTADTKGTRSASFTTTNTTPQDEVSEATASRHRFPRFPSYEGSESAIEEEDEEEAKRSRRRRRYRRHRHRKSKKQARDAKKAAGVTEAQNELPENAPQNNSECEPRRVDFAVQDDLEAGPSNTGKRPFPLRGLSVKNIPPVFTEKSTVASTPVPHVRYGIRRTNSLPDRLQFRAPGAMLPSSVPPILTAPGAHMIAKEQENEEDHLTQSGAIILLLVSTALVAVCAEFLVDSIKEVVETSGVNEVGIGLIILPIVGNAAEHVTAIKVAYKNHMDLAIGVAVGSSIQIALLLTPVMVILGWIIDKDMSLYFTLFETVCLFVSAFIVNFLVLDGRSNYLEGALLCAVYIIIAVVAFFYPNE
Length728
PositionKinase
OrganismFusarium oxysporum f. sp. cubense (strain race 1) (Panama disease fungus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Nectriaceae> Fusarium> Fusarium oxysporum species complex.
Aromaticity0.06
Grand average of hydropathy-0.140
Instability index55.54
Isoelectric point6.81
Molecular weight78859.69
Publications
PubMed=24743270

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW

GO - Biological Function
GO - Biological Process
transmembrane transport	GO:0055085	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP31905
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      84.57|      25|      27|     381|     406|       1
---------------------------------------------------------------------------
  381-  402 (30.98/16.66)	......................SFTTT.....NTTPQDE.VSEATASRHR
  404-  430 (30.63/18.73)	PRF..................pSYEGS.....ESAIEEEdEEEAKRSRRR
  431-  478 (22.96/ 7.40)	RRYrrhrhrkskkqardakkaaGVTEAqnelpENAPQNN..SECEPRRVD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.81|      25|      27|     498|     523|       2
---------------------------------------------------------------------------
  499-  523 (43.03/31.37)	LR.GLSVKN.IPPVFTEKSTVASTP..VP
  525-  553 (31.77/15.68)	VRyGIRRTNsLPDRLQFRAPGAMLPssVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.67|      33|      34|     129|     162|       3
---------------------------------------------------------------------------
  129-  162 (50.55/37.15)	LNILLIFVPVGIAVSQVDGING..GIVFGlNAVAII
  164-  198 (49.13/31.42)	LAGLLAYATESVARKMGDALGAllNVTFG.NAVELI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.07|      14|      30|     331|     347|       5
---------------------------------------------------------------------------
  331-  347 (19.90/17.20)	SSSSSSDSSDsdsSHGT
  364-  377 (24.16/12.30)	SSTASVDTAD...TKGT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.79|      14|      16|      44|      59|       6
---------------------------------------------------------------------------
   44-   59 (22.40/18.14)	NGSS..GSVNGGDrqGPS
   61-   76 (20.39/ 9.63)	NNSSllKALSAGD..IPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.93|      25|      30|     590|     617|       7
---------------------------------------------------------------------------
  590-  617 (32.41/32.41)	LVAVCAEFlVDSIKevVETSGVNEVGIG
  623-  647 (42.52/29.24)	IVGNAAEH.VTAIK..VAYKNHMDLAIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.42|      20|      38|     241|     260|       8
---------------------------------------------------------------------------
  241-  260 (33.59/25.39)	SACLLSLSVISLVLPTAFHA
  280-  299 (33.82/25.62)	SIVLLLVYVIYLMFQLKSHA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP31905 with Med13 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AGLLDSSSSDDSSSSSSDSSDSDSSHGTMRKKMKKVLRNRRHRRSSTASVDTADTKGTRSASFTTTNTTPQDEVSEATASRHRFPRFPSYEGSESAIEEEDEEEAKRSRRRRRYRRHRHRKSKKQARDAKKAAGVTEAQNELPENAPQNNSECEPRRVDFAVQDDLEAGPSNTGKRPFPLRGLSVK
2) MKEASPDPPNIDGSRSGAQPAAPTAQGLNEHSNTQHKEFNEKQNGSSGSVNGGDRQGPSRNNSSLLKALSAGDIPSHTASQAARPGSVIETPNKAEEPSQENPNPTSKMN
320
1
505
110










Molecular Recognition Features






MoRF SequenceStartStop




1) APTAQGLNEHSNTQHKEFN
2) RRHRHRKSKKQARDAKKA
22
434
40
451