<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31895

Description Pkinase-domain-containing protein
SequenceMTSTNNNPPSVPPPGPAAPAPLLPSAPPSVGPIPPTHSLKRGAPAAVDEADAPSLVRMNATPYAPQRHINDNYDIVGFISSGTYGRVYKAVNKRGVHQANPAKHPDGRPIEAFAIKKFKPDKEGELQYTGISQSAIREMALCTELSHPALIHLVEIILEAKCIFMVFEYAEHDLLQIIHHHSLLPRTPIPASTLRSCMYQIFSGLLYLHQNWVIHRDLKPANIMVTSGGAIKIGDLGLARLFWKPLHALFSGDKVVVTIWYRAPELLLGSRHYTPAIDLWAVGCIFAELLSLRPIFKGEEAKQDSKKAVPFQRNQMGKIGEILGLPRKNEWPLLASMPEYPNLSSVSMHNPAVNRPMGLEKWYRNTLQNNHYGRNAPDDSALDLLKSLLRYDPLKRMTAEQALQHPYFTAGIGTGGGGGGYSSFSPSTTTTATTSSSSAAATAAAGATAKIQALYSNCFEGLENKYPPRKVSTEAHNEIGTTTTAATTNHNSAVTGSKRSAAIQQQAQQAQQQQQQQQQQQQQDERLLGPVQKKMRDG
Length538
PositionKinase
OrganismSphaerulina musiva (strain SO2202) (Poplar stem canker fungus) (Septoria musiva)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes> Dothideomycetidae> Mycosphaerellales> Mycosphaerellaceae> Sphaerulina.
Aromaticity0.07
Grand average of hydropathy-0.386
Instability index51.77
Isoelectric point9.24
Molecular weight58800.29
Publications
PubMed=23236275

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP31895
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.31|      12|      15|       8|      19|       1
---------------------------------------------------------------------------
    8-   19 (28.01/12.46)	PPSVPPPGP......AAP
   27-   44 (21.30/ 7.79)	PPSVGPIPPthslkrGAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.80|      15|      15|     217|     231|       2
---------------------------------------------------------------------------
  217-  231 (25.90/14.21)	DLKPANIM......VTSGGAI
  235-  255 (18.89/ 8.81)	DLGLARLFwkplhaLFSGDKV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.76|      16|      19|     101|     118|       4
---------------------------------------------------------------------------
  101-  118 (23.91/23.59)	PAKhpDGR....PIEAFAIKKF
  120-  139 (22.85/13.39)	PDK..EGElqytGISQSAIREM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.95|      26|      51|     428|     453|       5
---------------------------------------------------------------------------
  428-  453 (41.13/23.25)	TTTTATTSSSSAAATAAAGATAKIQA
  482-  507 (43.82/25.17)	TTTAATTNHNSAVTGSKRSAAIQQQA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP31895 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KYPPRKVSTEAHNEIGTTTTAATTNHNSAVTGSKRSAAIQQQAQQAQQQQQQQQQQQQQDERLLGPVQKKMRDG
2) MTSTNNNPPSVPPPGPAAPAPLLPSAPPSVGPIPPTHSLKRGAPAAVDEADAPSLVRMNATPY
465
1
538
63










Molecular Recognition Features






MoRF SequenceStartStop




1) RLLGPVQKKMRD
526
537