<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31848
Description |
Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MEELSQANPLATVFPAPPPFYQSFTPTNIQKFAAHRAKVLGSEKNVASDASTLLADLPAELVHLQPPELPSAEEGKFRCFGDVYYIFGKVKEDLPSLEAMGVEQVYTPPTSPARIQSPSQDLQAHHDRAFILKRLAKSLLLNFLELLGVLATNPSLWTQKVQDIRTLAINFHHLLNEYRPHQARESLIMIMREQLAKKKAEIQSVRECGERVEKILEGLGSISLDEPKVYEKEPEVDVEEIIWESMEKELA |
Length | 251 |
Position | Middle |
Organism | Blumeria graminis f. sp. hordei (strain DH14) (Barley powdery mildew) (Oidium monilioides f. sp. hordei) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Leotiomycetes>
Erysiphales> Erysiphaceae> Blumeria.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.302 |
Instability index | 49.61 |
Isoelectric point | 5.27 |
Molecular weight | 28326.14 |
Publications | PubMed=21148392
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364060
ECO:0000256 ARBA:ARBA00003669
|
GO - Cellular Component | core mediator complex GO:0070847 IEA:EnsemblFungi
mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | negative regulation of transcription by RNA polymerase II GO:0000122 IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II GO:0045944 IEA:EnsemblFungi
|
Interaction
Repeat regions
Repeats |
>MDP31848
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 165.48| 42| 45| 60| 102| 1
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18- 63 (48.08/29.95) .PPFYQS...FTPTNIQKFaAHRAKVLGsekNVASD..ASTLLAdLPAELVH
65- 106 (72.08/50.08) QPPELPS...AEEGKFRCF.GDVYYIFG...KVKED..LPSLEA.MGVEQVY
107- 149 (45.32/24.70) TPPTSPAriqSPSQDLQAH.HDRAFILK...RLAKSllLNFLEL.LGV....
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