<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31803
Description |
Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MADADAQRQAEEDANLQLPPYPHPPPFYLKFTTENKDRLDEIKKEDGIDTASDGGKSAQLSTEQILALPTELRYLIPPEPPADTEEFNVFGTINQLKDRDTFNGTMEYISQALAKLLPDWKYEQLYPTTDASNSASSTLDRQRYLFRFLRSILVAYIELLGIVAINPTDELKDDKLKDILTMVTNMHALINEYRPHQARETLISEMERQVEKKKMEIQGVRKMKERVGEVLEGFGREIPSEKAEDRTEEAAVTSEEERKRDAQRQMWQAMDEMLSQ |
Length | 276 |
Position | Middle |
Organism | Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes>
Pleosporomycetidae> Pleosporales> Pleosporineae> Phaeosphaeriaceae>
Parastagonospora.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.764 |
Instability index | 46.46 |
Isoelectric point | 4.75 |
Molecular weight | 31788.42 |
Publications | PubMed=18024570
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors (By similarity).
ECO:0000250
|
GO - Cellular Component | core mediator complex GO:0070847 IBA:GO_Central
mediator complex GO:0016592 IBA:GO_Central
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IBA:GO_Central
|
Interaction
Repeat regions
Repeats |
>MDP31803
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 105.91| 32| 113| 53| 86| 1
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53- 86 (50.52/41.02) DGGKSAQLstEQILALPTELRYLIPPEPPADTEE
169- 200 (55.39/38.35) DELKDDKL..KDILTMVTNMHALINEYRPHQARE
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