<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31697
Description |
Mediator of RNA polymerase II transcription subunit 31 |
Sequence | MAEVATAEKPVTDGIQDGSEQPDRSLRFEAELEFVQSLANPQYLSYLAHNKYLESPEFLNYLSYLEYWREPKYARFLVYPNCLHVLKLLQYATFRKEISRPDFAKQLMDEFYYAWIKPSEAGVFGDDDTLEGLKREDSQAPPGQNVKMENKDGDGDVQMA |
Length | 160 |
Position | Middle |
Organism | Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes>
Saccharomycetales> Dipodascaceae> Yarrowia.
|
Aromaticity | 0.13 |
Grand average of hydropathy | -0.657 |
Instability index | 55.62 |
Isoelectric point | 4.62 |
Molecular weight | 18520.50 |
Publications | PubMed=15229592
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors (By similarity).
ECO:0000250
|
GO - Cellular Component | core mediator complex GO:0070847 IBA:GO_Central
mediator complex GO:0016592 IBA:GO_Central
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IBA:GO_Central
|
Interaction
Repeat regions
Repeats |
>MDP31697
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 142.97| 34| 76| 21| 54| 1
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21- 54 (55.62/37.14) QPDRSLRFEAEL..EFVQSLANPQYLSYLAHNKYLE
69- 99 (42.46/26.79) ...REPKYARFL..VYPNCLHVLKLLQYATFRKEIS
100- 131 (44.89/28.70) RPD....FAKQLmdEFYYAWIKPSEAGVFGDDDTLE
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