Description | Mediator of RNA polymerase II transcription subunit 31 |
Sequence | MEESLPKRWEIELEFVQSLANIQYLNHLAQNNYLSNPEFLNYIEYLNYWKEPEYSKYLVYPNCLHILTLLQNEEFRKNILIPDFMNTVMNDMVKRWQDQDSVFGVTPQSQLEGLNASNGDDTNQPSVEVNGSGSN |
Length | 135 |
Position | Middle |
Organism | Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Debaryomyces. |
Aromaticity | 0.12 |
Grand average of hydropathy | -0.616 |
Instability index | 66.61 |
Isoelectric point | 4.38 |
Molecular weight | 15827.44 |
Publications | PubMed=15229592 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors (By similarity).
ECO:0000250 |
GO - Cellular Component | core mediator complex GO:0070847 IEA:EnsemblFungi mediator complex GO:0016592 IEA:EnsemblFungi |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | DNA repair GO:0006281 IEA:EnsemblFungi meiotic gene conversion GO:0006311 IEA:EnsemblFungi meiotic sister chromatid segregation GO:0045144 IEA:EnsemblFungi regulation of transcription, DNA-templated GO:0006355 IEA:InterPro transcription by RNA polymerase II GO:0006366 IEA:EnsemblFungi |
Binary Interactions |
Repeats | >MDP31684 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 57.75| 15| 19| 19| 33| 1 --------------------------------------------------------------------------- 19- 33 (27.43/14.78) LANIQYLNHLAQNNY 40- 54 (30.31/16.92) LNYIEYLNYWKEPEY --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) DTNQPSVEVNGSGS 2) ILIPDF 3) NDMVKRWQDQDSVFGVTPQSQLEGLN | 121 79 90 | 134 84 115 |
© 2021 Shailesh Lab
Designed by Dr. Shailesh Lab & Dr. Jitendra K. Thakur Lab